N/A N=18 Predictors of Speech Ability in Down Syndrome
Speech Intelligibility Intervention in Down Syndrome
Primary: Speech Intelligibility — 3.59 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=215 Perceptual Training to Improve Listeners' Ability to Understand Speech Produced by Individuals With Dysarthria
Dysarthria · Intelligibility, Speech
Primary: Pretest Transcription Accuracy — 77.8; 35.3; 52.9; 30 percentage of words correct
N/A N=19 Manipulating Linguistic Complexity to Improve Child Language Treatment Outcomes
Language Development Disorders · Speech Sound Disorder
Primary: Treatment Probe Accuracy Change — 26; 23 percent accuracy of target consonants
N/A N=435 Application of Ideal Binary Masking to Disordered Speech
Hearing Loss, Sensorineural · Dysarthria
Primary: Percent Correct Speech Intelligibility — 69; 63 percentage of words correctly reported
N/A N=108 Correcting Residual Errors With Spectral, Ultrasound, Traditional Speech Therapy
Speech Sound Disorder
Primary: Change in F3-F2 Distance (Hz) Across Sessions, Measured From /r/ Sounds Produced in Syllables or Words During Practice. — 38.2; 66.7; 85.2 Hertz / session — p=< .0001
N/A N=10 Benefits of Assistive Listening Device for Speech Intelligibility
Hearing Loss
Primary: Speech Intelligibility in Noise — 58; 80; 27; 50 percentage of words correctly repeated — p=<0.01
Phase 1 N=14 Delineation of Sensorimotor Subtypes Underlying Residual Speech Errors
Speech Sound Disorder
Primary: Normalized F3-F2 Distance, an Acoustic Measure That Correlates With Perceptual Accuracy of /r/, Measured From /r/ Sounds Produced in Treatment Sessions. — 5.73; 6.27…
N/A N=84 Assessing Malleability of Spatial Abilities in Down Syndrome
Down Syndrome
Primary: Change in Mental Rotation Ability at 8 Weeks — 0.0; -0.6; .82 Amount of Change in Number Correct Items — p==.066
N/A N=42 A Pilot Study to Evaluate the Hypoglossal Nerve Stimulator in Adolescents With Down Syndrome and Obstructive Sleep Apnea
Sleep Apnea, Obstructive · Down Syndrome
Primary: Serious Adverse Events — 7 participants
N/A N=36 Optimizing Soft Speech Recognition in Children With Hearing Loss
Hearing Loss, Sensorineural · Hearing Loss, Bilateral
Primary: Speech Recognition in Quiet Using CNC (Consonant-Nucleus-Consonant) Word Lists — 6.06; 53.7; 66.61; 69.7 percentage of correctly repeated words — p=.005
N/A N=6 Gait in Children With Down Syndrome While Wearing Orthoses
Down Syndrome
Primary: Step Width — 10.4 cm
Phase 1 N=39 ASSIST: Treatment for Childhood Apraxia of Speech
Childhood Apraxia of Speech
Primary: Speech Accuracy of Treated Items — -0.7; 10.6; -2.8; -1.4 percentage of accuracy (change score) — p=0.0001
N/A N=20 Evaluation of Intensive Language Therapy
Parkinson's Disease
Primary: Velocity in Gait — 1.2; 1.2; 1.2; .8 meter per second — p=.05
N/A N=36 Treatment Intensity - Apraxia of Speech
Aphasia · CVA · Apraxia of Speech
Primary: Accuracy of Articulation of TREATED ITEMS Measured as Effect Size - Change From Baseline to End of Treatment Phase — 19.7; 28.9 effect sizes; magnitude of change — p=.0128
N/A N=758 Developing a Down Syndrome Health Instrument
Down Syndrome · Health, Subjective
Primary: Number of Completed Surveys for Validation Analysis — 0; 0; 542 Participants
N/A N=50 Spectral Dynamics and Speech Understanding by Hearing Impaired People
Hearing Loss, Sensorineural
Primary: Percent Correct Words Identified — 98.6; 97.1; 91.9; 98.8 percentage of words identified
N/A N=48 Kindergarten Children Acquiring Words Through Storybook Reading
Language Development Disorders
Primary: Change in Definition Scores From Pre- to 12-weeks Post-treatment — 2.50; 3.18; 5.50 number of words
N/A N=35 Accelerating Word Learning in Children With Language Impairment
Specific Language Impairment
Primary: Change in Words Known From Pre- to Post-treatment — 0.63; 0.78; 0.56; 0.38 Number of words learned — p=<0.05
N/A N=230 An Online Health Tool About Down Syndrome: Down Syndrome Clinic to You
Down Syndrome
Primary: Number of Participants With Indicated Evaluations That Were Completed or Recommended by the PCP — 69; 79; 36; 31 participants — p=0.018
N/A N=104 An RCT of a Telemedicine Intervention for Hypokinetic Dysarthria in PD
Parkinson's Disease
Primary: Change in Speech Intelligibility at 6 Months — 0.25; -4.78 score on a scale — p=0.13
Phase 2 N=188 Early Communication Intervention for Toddlers With Hearing Loss
Hearing Loss, Bilateral
Primary: Use of Communication Support Strategies - Parent — .60; .02 units on a scale
N/A N=48 Written Language Intervention for Adults With Intellectual and Developmental Disabilities
Intellectual Disability · Developmental Disability
Primary: Use of Reading Comprehension Strategies — 3.986; 0.032 reading comprehension strategies used
N/A N=8 Balance Bike Training in Down Syndrome
Down Syndrome · Postural Balance
Primary: Pediatric Balance Scale (PBS) Mean Group Score — 48.43; 49.43 score on a scale — p=<0.05
N/A N=10 Using the LENA System in Early Intervention - b
Depression
Primary: LENA Adult Word Count Score at 6 Weeks — 18391.25 number of words
Phase 2 N=40 Efficacy of AMALS in Treating Language Impairment in Children
Language Disorder
Primary: Language Sample Analysis — 17.33; 18.00; 39.35; 26.38 Percentage of utterances
N/A N=17 Use of Partial Body Weight Support Play Environment to Encourage Mobility and Exploration in Infants With Down Syndrome
Down Syndrome · Trisomy 21
Primary: Change in Movement Counts Per 15 Seconds From Baseline (Week 1) to Mid Study (Week 5) — -34.46; -88.62 movement counts per 15 seconds
N/A N=30 Penetrating the Classroom Social Network for Children With Language Impairment Via Peer Mediated Intervention
Peer Influence
Primary: Preschool Language Screener 5 (PLS-5) - Growth Scale Value — 437.09; 455.38; 459.09; 464.77 score on a scale — p=.84
Phase 1 N=34 Speech Recognition Training in Children With Hearing Loss
Hearing Loss
Primary: Percentage of Words Identified Before and After Training — 49.7; 55.7 percentage of words presented
N/A N=23 Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome
Down Syndrome · Obstructive Sleep Apnea Syndrome
Primary: Change in Epworth Sleepiness Scale From Baseline to End of Study — -1; -0.5; 1 units on a scale
N/A N=56 Treating Childhood Apraxia of Speech
Childhood Apraxia of Speech
Primary: Speech Sound Accuracy — 54.1; 32.5; 26.8; 42.1 Percent correct — p=.132