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Opium use and disorder prevalence remains high among Iranian men despite declining trends in studentsData Shows Declining Opium Use Among Iranian University Students

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Key Takeaway
Note high opium use rates in the Iranian population despite declining trends among university students.

This meta-analysis synthesized data from 115 studies to determine the prevalence of opium use and opium use disorder within the Iranian population, including general populations and university students. The analysis focused on identifying current usage rates and longitudinal trends among specific demographics.

Key findings indicate a 8.4% prevalence of 12-month opium use in men (95% CI 5.1-12.6%) and a 3.7% prevalence of opium use disorder in men (95% CI 1.6-6.5%). In contrast, women showed lower rates of 1.1% for usage and 0.4% for disorder. Among university students, the reported 12-month usage was 2.3% for men and 0.6% for women.

Regarding longitudinal trends from 2000 to 2018, male university students showed a decrease of 9.1 percentage points in lifetime opium use (95% CI -18.6 to 0.4) and a decrease of 8.6 percentage points in current daily or almost daily opium use (95% CI -11.8 to -5.3).

The authors note high heterogeneity for both men's and women's 12-month usage, with I-squared values of 97.2% and 95.1%, respectively. Despite the observed decline in use among younger populations, the overall prevalence remains high, which may impact clinical resource planning.

How this fits prior evidence

This meta-analysis addresses a gap in regional data regarding opium use specifically within Iran. While prior evidence suggests that plant-derived compounds show potential for substance use disorders, this study provides specific prevalence data and identifies a downward trend in usage among younger Iranian students from 2000 to 2018.

A large review of 115 studies looked at how many people in Iran used opium or had an opium use disorder. The researchers found that while usage remains common, there are notable differences between groups. For example, about 8.4% of men and 1.1% of women in the general population reported using opium in the last year.

Among university students, the numbers were lower, with 2.3% of men and 0.6% of women reporting use in the last 12 months. However, the data also showed a downward trend for younger people. Specifically, among male university students between 2000 and 2018, both lifetime opium use and daily usage dropped by about 9 percentage points.

It is important to note that these findings come from a meta-analysis, which combines many different studies. Because the original studies varied greatly in how they were conducted, the results should be viewed as a broad overview of trends rather than a precise prediction for every individual.

What this means for you:
Opium use is declining among some younger students even though usage remains high in the general population.

Common questions

What are the current rates of opium use in Iran?

In the general population, 8.4% of men and 1.1% of women reported using opium in the last 12 months. Among university students, these figures were lower, with 2.3% for men and 0.6% for women.

Is opium use decreasing among younger people?

Yes, the data shows a downward trend for male university students between 2000 and 2018. Both lifetime opium use and daily or almost daily usage dropped by approximately 9 percentage points during that period.

How reliable is this information?

The findings come from a meta-analysis of 115 studies. Because the original studies had high levels of variation, the results show general trends rather than specific certainties for every individual.

Study Details

Study typeMeta analysis
EvidenceLevel 1
Follow-up12.0 mo
PublishedAug 2026
View Original Abstract ↓
BACKGROUND AND AIMS: Despite historical and cultural roots, there is limited comprehensive data on the prevalence of opium use and use disorder across the Iranian population. We systematically reviewed the prevalence and trends of opium use and use disorder in Iran. METHOD: Systematic review and meta-analysis adhering to PRISMA guidelines, including studies from 1990 to 2023 across the Iranian general population, university students, the young population and specific populations. Measurements included the prevalence of opium use and use disorder by sex, time indicators (lifetime, last 12 months, last month/current, current daily or almost daily), study year and population subgroups. RESULTS: A total of 115 studies were included. Pooled prevalence of last 12-month opium use among the general population was 8.4% [95% confidence interval (CI) = 5.1-12.6%, studies = 6, n = 9302, I = 97.2%] in men and 1.1% (95% CI = 0.4-2.3%, studies = 7, n = 13 129, I = 95.1%) in women. The prevalence of the last 12-month opium use disorder was 3.7% (95% CI = 1.6-6.5%, studies = 3, n = 9605, I = 97.7%) and 0.4% (95% CI = 0.1-0.8%, studies = 3, n = 10 465, I = 81.0%) among male and female Iranian general population, respectively. Last 12-month opium use was 2.3% (95% CI = 1.5-3.3%, studies = 13, n = 37 164, I = 83.3%) in male and 0.6% (95% CI = 0.2-1.0%, studies = 13, n = 43 471, I = 85.4%) in female university students. Among male university students, lifetime opium use declined by 9.1 percentage points between 2000 and 2018 (95% CI = -18.6 to 0.4), while current daily or almost daily use decreased by 8.6 percentage points over the same period (95% CI = -11.8 to -5.3). CONCLUSIONS: Despite global shifts to harder opioids, opium use continues to have a very high prevalence among the Iranian general population. While the overall prevalence appears stable, younger generations have shown a declining use pattern.
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