When we think of cancer, we usually think of cells growing out of control. However, researchers are looking closer at the environment surrounding those cells. They are investigating how fungi, the tiny organisms that live in and on our bodies, might interact with tumors in colorectal, gastric, and pancreatic cancers.
In colorectal cancer, studies show clear changes in fungal communities and how they interact with bacteria. For gastric cancer, a specific fungus called Candida albicans is being watched as a potential signal in tissue. In pancreatic cancer, researchers have found fungal signals in human tissue, though some of the strongest evidence for specific immune responses currently comes from mouse models.
It is important to note that finding a fungus in a sample does not mean it is causing the cancer or is even alive. Because of issues like low fungal amounts and potential contamination, the evidence is still early. More research is needed to see if these fungal markers can actually help doctors treat patients better than current methods.