Apixaban Plasma Levels Elevated in Medicare Patients Taking CYP3A4 and P-gp Inhibitors
Higher Drug Levels Mean More Bleeding Risk
This pilot cohort study evaluated 35 Medicare patients with atrial fibrillation receiving apixaban 5mg BID. Apixaban plasma concentrations w…
Taking common heart rhythm drugs with apixaban raises blood levels and increases the risk of serious bleeding that can lead to hospitalizati…
In CRT recipients with persistent AF, rhythm control improved LVEF compared to rate control strategies.
Does fixing your heart rhythm actually improve pump function in this specific group?
This randomized trial evaluated rhythm versus rate control strategies in 43 CRT recipients with long-standing persistent AF and low biventri…
Fixing irregular heartbeats boosted heart muscle strength in patients with devices, but daily life and exercise ability improved similarly w…
Systematic review finds evidence gap for amiodarone in chronic Chagas cardiomyopathy
Review finds major research gap on heart drug amiodarone for Chagas disease
A systematic review and bibliometric analysis of 52 articles identified a significant literature gap regarding amiodarone therapy for chroni…
A review of 52 studies found a significant lack of rigorous clinical research on using the heart drug amiodarone for Chagas cardiomyopathy. …