Pulsed field ablation beats antiarrhythmic drugs as first-line persistent AF therapy
Pulsed field ablation shows higher success than drugs for heart rhythm
In a randomized trial of 207 patients with previously untreated persistent atrial fibrillation, pulsed field ablation (PFA) achieved 56% tre…
A new trial shows pulsed field ablation provides a much higher success rate than standard drugs for patients with persistent atrial fibrilla…
Meta-analysis shows VOM ethanol infusion improves sinus rhythm maintenance in persistent AF ablation
Ethanol infusion improves rhythm control in persistent AF
This meta-analysis evaluated VOM ethanol infusion versus PVI with or without linear ablation in patients undergoing catheter ablation for pe…
Adding ethanol to standard ablation helps more people with persistent AF stay in sinus rhythm during the first year.
Rotational activity ablation added to PVI shows 91.5% sinus rhythm in persistent AF cohort
Stop AF by Targeting Hidden Heart Spins
A prospective multicenter cohort study of 76 patients with persistent AF found that adding rotational activity (RotAct) ablation to pulmonar…
Targeting hidden heart spins during ablation improved outcomes for atrial fibrillation patients, with 38% showing these spins before treatme…
Combined LAPVI improved sinus rhythm maintenance versus PVI alone in persistent AF patients
Combined Ablation Technique Improves Rhythm Control in Persistent Atrial Fibrillation Patients
This randomized controlled trial evaluated 228 patients with persistent atrial fibrillation comparing combined Left Atrial Posterior Wall Li…
Adding a specific linear ablation to standard heart surgery helps 75% of persistent atrial fibrillation patients maintain normal rhythm comp…
Indirect comparison suggests Sphere-9 PFA catheter may have higher efficacy than Farawave for persistent AF
Two pulsed field ablation systems compared indirectly for persistent atrial fibrillation
A matched-adjusted indirect comparison of two pulsed field ablation (PFA) systems for symptomatic persistent atrial fibrillation found the S…
Patients treated with the Sphere-9 pulsed field ablation system had a 77.4% success rate at 12 months, compared to 63.5% for the Farawave sy…
Research across Atrial Fibrillation
Related studies from across the Atrial Fibrillation family.
Thoracic Radiotherapy Linked to 7.6% Pooled Incidence of Reported Atrial Fibrillation
Thoracic radiation for cancer may increase risk of heart rhythm issues
This meta-analysis of 9 cohort-level estimates examines reported atrial fibrillation after thoracic radiotherapy in adults with thoracic mal…
New data shows that patients receiving radiation for chest cancers may face a higher risk of developing atrial fibrillation, a common heart …
Composite lipid and metabolic indices show more consistent associations with atrial fibrillation recurrence than individual measures
Lipid Profiles May Reflect Metabolic Burden in Atrial Fibrillation
This narrative review examines the relationship between circulating lipid profiles and atrial fibrillation risk or post-ablation recurrence.…
New research suggests that lipid levels in the blood may reflect overall metabolic health rather than acting as direct causes of heart rhyth…
Pulsed-field ablation shows shorter ablation times and lower phrenic nerve palsy than cryoballoon ablation
Pulsed-field Ablation Shows Faster Times for Atrial Fibrillation Treatment
This meta-analysis of 2024 patients with atrial fibrillation undergoing pulmonary vein isolation compares pulsed-field ablation (PFA) to cry…
A new analysis suggests pulsed-field ablation may offer faster procedure times and lower nerve damage risks for patients with atrial fibrill…
Clinical risk factors including smoking and sleep apnea increase arrhythmia recurrence after atrial fibrillation ablation
Clinical risk factors linked to higher atrial fibrillation recurrence rates
This meta-analysis examined various clinical risk factors and their impact on arrhythmia recurrence in patients undergoing catheter ablation…
Specific health conditions like sleep apnea and gum disease are linked to a higher risk of heart rhythm issues returning after surgery.
Early oral anticoagulants show no significant difference in stroke risk compared to late initiation
Early blood thinners show no extra risks for stroke patients
This meta-analysis of 6522 adults with atrial fibrillation and recent ischemic stroke found no significant difference in recurrent ischemic …
Starting blood thinners soon after a stroke does not increase the risk of bleeding or death compared to waiting.
DOACs reduce device-related thrombosis and bleeding risk compared to DAPT after left atrial appendage closure
DOACs Show Lower Risk of Blood Clots After Heart Procedure
This meta-analysis of 704 patients with atrial fibrillation undergoing percutaneous left atrial appendage closure found that DOACs significa…
Patients with atrial fibrillation may have a lower risk of blood clots and bleeding when using DOACs after a specific heart procedure.
DOACs reduce stroke, mortality, and major bleeding risk compared to vitamin K antagonists in hemodialysis
DOACs Show Lower Stroke and Bleeding Risk in Dialysis Patients
This meta-analysis evaluated the efficacy and safety of direct oral anticoagulants (DOACs) compared to vitamin K antagonists in patients wit…
Patients with atrial fibrillation on hemodialysis may have lower risks of stroke and major bleeding when using DOACs instead of vitamin K an…
Digital recruitment strategy yielded 1,406 registrations from 1,319 potential individuals with atrial fibrillation
Digital Ads Help Recruit Patients for Atrial Fibrillation Trials
This observational feasibility study evaluated digital recruitment strategies using online advertisements and a pre-screening website for at…
New data shows digital advertising can help find more diverse participants for atrial fibrillation clinical trials, though some gaps remain.
Double-chambered left ventricle in adulthood with severe mitral regurgitation and refractory heart failure
Complex heart structure can cause severe heart failure in adults
This case report describes a 50-year-old man with longstanding atrial fibrillation and heart failure with reduced ejection fraction, found t…
A man with a rare double-chambered heart and chronic irregular heartbeat showed that complex anatomy can lead to severe heart failure.
Adding antiplatelet therapy to anticoagulation does not cut stroke risk but raises major bleeding
Combined Anticoagulant and Antiplatelet Therapy Increases Bleeding Risk
This meta-analysis of 14,884 patients with recent ischemic stroke, nonvalvular atrial fibrillation, and large artery atherosclerosis found t…
Combining two types of blood thinners may increase bleeding risks without reducing the chance of a second stroke in patients with certain he…
Postoperative atrial fibrillation increases long-term thromboembolic risk following CABG and isolated valve surgery
Atrial Fibrillation After Heart Surgery Linked to Higher Blood Clot Risk
This meta-analysis of observational studies indicates that postoperative atrial fibrillation (POAF) is associated with increased long-term t…
New analysis suggests that patients who develop atrial fibrillation after heart surgery face a higher risk of long-term blood clots.
DOACs associated with lower risks of recurrent ICH, ischemic stroke, and mortality in atrial fibrillation
Trial Shows Direct Oral Anticoagulants Reduce Risks for Atrial Fibrillation
This meta-analysis evaluates the efficacy of direct oral anticoagulants (DOACs) compared to vitamin K antagonists (VKAs) in patients with at…
New data suggests that direct oral anticoagulants may lower the risk of stroke and bleeding for patients with atrial fibrillation.
Questions about Persistent Atrial Fibrillation
Can ethanol infusion during ablation improve rhythm maintenance for patients with persistent atrial fibrillation?
Yes, adding ethanol infusion in the vein of Marshall during ablation improves sinus rhythm maintenance in persistent AF patients, with a 17% absolute benefit at 1 year.
Full answer →What is the success rate for sinus rhythm when adding rotational activity ablation for persistent AF?
Adding rotational activity ablation to standard procedures increases the rate of sinus rhythm maintenance to 91.5% in persistent AF patients, compared to lower rates with standard ablation alone.
Full answer →Does VOM ethanol infusion help keep a normal heart rhythm in persistent atrial fibrillation?
Adding VOM ethanol infusion to standard catheter ablation improves the chance of keeping a normal heart rhythm in persistent atrial fibrillation.
Full answer →