Meta-analysis shows VOM ethanol infusion improves sinus rhythm maintenance in persistent AF ablation
Ethanol infusion improves rhythm control in persistent AF
This meta-analysis evaluated VOM ethanol infusion versus PVI with or without linear ablation in patients undergoing catheter ablation for pe…
Adding ethanol to standard ablation helps more people with persistent AF stay in sinus rhythm during the first year.
Rotational activity ablation added to PVI shows 91.5% sinus rhythm in persistent AF cohort
Stop AF by Targeting Hidden Heart Spins
A prospective multicenter cohort study of 76 patients with persistent AF found that adding rotational activity (RotAct) ablation to pulmonar…
Targeting hidden heart spins during ablation improved outcomes for atrial fibrillation patients, with 38% showing these spins before treatme…
Combined LAPVI improved sinus rhythm maintenance versus PVI alone in persistent AF patients
Combined Ablation Technique Improves Rhythm Control in Persistent Atrial Fibrillation Patients
This randomized controlled trial evaluated 228 patients with persistent atrial fibrillation comparing combined Left Atrial Posterior Wall Li…
Adding a specific linear ablation to standard heart surgery helps 75% of persistent atrial fibrillation patients maintain normal rhythm comp…
Indirect comparison suggests Sphere-9 PFA catheter may have higher efficacy than Farawave for persistent AF
Two pulsed field ablation systems compared indirectly for persistent atrial fibrillation
A matched-adjusted indirect comparison of two pulsed field ablation (PFA) systems for symptomatic persistent atrial fibrillation found the S…
Patients treated with the Sphere-9 pulsed field ablation system had a 77.4% success rate at 12 months, compared to 63.5% for the Farawave sy…
Research across Atrial Fibrillation
Related studies from across the Atrial Fibrillation family.
SGLT2 inhibitors provide robust prognostic benefits in heart failure with inconsistent results in post-myocardial infarction settings
SGLT2 inhibitors show promise for heart failure and diabetes
This narrative review examines the cardiovascular and metabolic effects of SGLT2 inhibitors, specifically empagliflozin and dapagliflozin. T…
New evidence shows how SGLT2 inhibitors may protect the heart and manage risks for patients with type 2 diabetes and heart failure.
Incidental arrhythmia findings on ambulatory ECG vary widely in adults without prior atrial fibrillation
Hidden heart rhythm problems found in up to 96% of adults
This systematic review and meta-analysis of 136,344 community-based adults without prior atrial fibrillation found that the prevalence of in…
A review of 136,344 adults found hidden heart rhythm issues in up to 96% of people without known atrial fibrillation.
Renal denervation combined with pulmonary vein isolation increases freedom from atrial fibrillation risk in resistant hypertension patients
Renal denervation may help resistant hypertension patients with heart issues
This systematic review and meta-analysis evaluated renal denervation in patients with resistant hypertension. The pooled analysis included 8…
A meta-analysis suggests renal denervation improves heart and sleep markers in patients with resistant hypertension, though larger trials ar…
Hypertension history associates with 2.22-fold higher cognitive impairment risk in AF patients
High blood pressure history doubles dementia risk in atrial fibrillation patients
This systematic review and meta-analysis of observational studies found that a history of hypertension is associated with an increased risk …
A history of high blood pressure is linked to a much higher risk of cognitive impairment in people with atrial fibrillation, according to a …
Left atrial appendage occlusion and NOACs reduce mortality compared with warfarin in atrial fibrillation
LAAO, low-dose NOACs beat warfarin for atrial fibrillation survival
A network meta-analysis compared left atrial appendage occlusion (LAAO), low-dose NOACs, standard-dose NOACs, and warfarin in non-valvular a…
For people with atrial fibrillation, warfarin may be the worst option for survival. New analysis finds LAAO and NOACs outperform it.
Pulsed-field ablation shows no significant AKI difference versus radiofrequency ablation in AF
Pulsed-field ablation shows similar kidney risk as radiofrequency ablation
This systematic review and meta-analysis of 3,843 patients found no significant difference in acute kidney injury (AKI) between pulsed-field…
A large review found no major difference in kidney injury risk between two heart rhythm treatments, though one method showed slightly higher…
Discontinuing oral anticoagulation after AF ablation reduces bleeding without increasing thromboembolic risk
Stopping blood thinners after heart rhythm repair cuts bleeding risk without raising stroke danger
This systematic review and meta-analysis evaluated patients who stopped versus continued oral anticoagulation following atrial fibrillation …
A massive analysis shows stopping blood thinners after heart rhythm repair cuts bleeding risk without raising stroke danger for many patient…
Narrative review on atrial fibrillation and depression highlights bidirectional links and integrated care needs
Depression and heart rhythm problems may worsen each other
This narrative review synthesizes evidence on the bidirectional relationship between atrial fibrillation and depression. It suggests depress…
A new review suggests depression and atrial fibrillation can fuel each other, making it vital to screen for both conditions together.
LAAC shows noninferior efficacy and reduced bleeding versus NOACs in non-valvular AF
New data shows left atrial appendage closure offers bleeding safety for some adults with atrial fibrillation
This meta-analysis of RCTs in adults with non-valvular AF found percutaneous left atrial appendage closure (LAAC) achieved noninferiority fo…
A large review of trials found that closing the heart appendage reduced bleeding compared to blood thinners. However, stroke risk trends wer…
Edoxaban trough concentration and PT predict major bleeding in very old AF patients
Blood thinner levels linked to bleeding in very old patients
This post hoc analysis of the ELDERCARE-AF RCT included 427 very old Japanese patients with atrial fibrillation and high bleeding risk. High…
Higher edoxaban levels in the blood may increase bleeding risk in patients 80 and older with atrial fibrillation.
Review links metabolic syndrome to 1.5 to 2 times higher atrial fibrillation risk
Metabolic syndrome raises atrial fibrillation risk by 1.5 to 2 times
This narrative review examines the association between metabolic syndrome and atrial fibrillation. The authors synthesize evidence suggestin…
Metabolic syndrome increases the risk of developing atrial fibrillation by 1.5 to 2 times, a finding that could help doctors target preventi…
Editorial argues emergency physicians are key to AF heart teams
Emergency doctors key to atrial fibrillation care, editorial says
This editorial argues that emergency physicians are indispensable members of atrial fibrillation heart teams. They enhance integration of ac…
An editorial argues emergency physicians should be core members of AF heart teams to improve care coordination and outcomes.
Questions about Persistent Atrial Fibrillation
Can ethanol infusion during ablation improve rhythm maintenance for patients with persistent atrial fibrillation?
Yes, adding ethanol infusion in the vein of Marshall during ablation improves sinus rhythm maintenance in persistent AF patients, with a 17% absolute benefit at 1 year.
Full answer →What is the success rate for sinus rhythm when adding rotational activity ablation for persistent AF?
Adding rotational activity ablation to standard procedures increases the rate of sinus rhythm maintenance to 91.5% in persistent AF patients, compared to lower rates with standard ablation alone.
Full answer →Does VOM ethanol infusion help keep a normal heart rhythm in persistent atrial fibrillation?
Adding VOM ethanol infusion to standard catheter ablation improves the chance of keeping a normal heart rhythm in persistent atrial fibrillation.
Full answer →