Pulsed field ablation beats antiarrhythmic drugs as first-line persistent AF therapy
Pulsed field ablation shows higher success than drugs for heart rhythm
In a randomized trial of 207 patients with previously untreated persistent atrial fibrillation, pulsed field ablation (PFA) achieved 56% tre…
A new trial shows pulsed field ablation provides a much higher success rate than standard drugs for patients with persistent atrial fibrilla…
Meta-analysis shows VOM ethanol infusion improves sinus rhythm maintenance in persistent AF ablation
Ethanol infusion improves rhythm control in persistent AF
This meta-analysis evaluated VOM ethanol infusion versus PVI with or without linear ablation in patients undergoing catheter ablation for pe…
Adding ethanol to standard ablation helps more people with persistent AF stay in sinus rhythm during the first year.
Rotational activity ablation added to PVI shows 91.5% sinus rhythm in persistent AF cohort
Stop AF by Targeting Hidden Heart Spins
A prospective multicenter cohort study of 76 patients with persistent AF found that adding rotational activity (RotAct) ablation to pulmonar…
Targeting hidden heart spins during ablation improved outcomes for atrial fibrillation patients, with 38% showing these spins before treatme…
Combined LAPVI improved sinus rhythm maintenance versus PVI alone in persistent AF patients
Combined Ablation Technique Improves Rhythm Control in Persistent Atrial Fibrillation Patients
This randomized controlled trial evaluated 228 patients with persistent atrial fibrillation comparing combined Left Atrial Posterior Wall Li…
Adding a specific linear ablation to standard heart surgery helps 75% of persistent atrial fibrillation patients maintain normal rhythm comp…
Indirect comparison suggests Sphere-9 PFA catheter may have higher efficacy than Farawave for persistent AF
Two pulsed field ablation systems compared indirectly for persistent atrial fibrillation
A matched-adjusted indirect comparison of two pulsed field ablation (PFA) systems for symptomatic persistent atrial fibrillation found the S…
Patients treated with the Sphere-9 pulsed field ablation system had a 77.4% success rate at 12 months, compared to 63.5% for the Farawave sy…
Research across Atrial Fibrillation
Related studies from across the Atrial Fibrillation family.
Metabolic syndrome increases risk of incident atrial fibrillation by 1.4- to 1.9-fold
Metabolic Syndrome Increases Risk of Atrial Fibrillation in Patients
This narrative review examines the association between metabolic syndrome and atrial fibrillation incidence. The authors synthesize evidence…
Metabolic syndrome is linked to a higher risk of atrial fibrillation, with high blood pressure and abdominal obesity showing the strongest c…
Conscious or deep sedation reduces procedural time in pulsed field ablation for atrial fibrillation
Comparing Sedation and General Anesthesia for Pulsed Field Ablation of Atrial Fibrillation
This meta-analysis of 10 studies involving 3,692 patients found that conscious or deep sedation (CS/DS) significantly shortened overall proc…
Doctors are finding that using light sedation instead of full general anesthesia can speed up heart procedures without hurting safety.
Yangxin Dingji plus conventional therapy reduces 6-month atrial fibrillation recurrence and improves LVEF
Yangxin Dingji Combined With Standard Care Shows Promise for Atrial Fibrillation
This meta-analysis of 872 patients evaluated Yangxin Dingji (YXDJ) as an adjunct to conventional therapy for atrial fibrillation. The study …
Adding Yangxin Dingji to standard treatment may improve symptoms and reduce the risk of heart rhythm recurrence in patients with atrial fibr…
Left atrial appendage occlusion reduces non-procedure-related bleeding but may increase ischemic stroke risk
LAAO Procedure Shows Mixed Results Compared to Oral Anticoagulants
This meta-analysis of 5,890 randomized patients evaluated left atrial appendage occlusion (LAAO) compared to oral anticoagulation for atrial…
A procedure called LAAO can reduce certain types of bleeding but may increase stroke risk compared to standard oral medications for heart pa…
Mortality Risk Factors in Atrial Fibrillation: Umbrella Review Findings
Specific risk factors linked to higher death rates in atrial fibrillation
An umbrella review found 86 of 216 risk factors significantly linked to mortality in atrial fibrillation, including several medications and …
New data identifies specific medications and health conditions that may increase the risk of death for people living with atrial fibrillatio…
Vascular closure devices reduce time to hemostasis by 5.63 minutes in atrial fibrillation ablation
Vascular closure devices speed up bleeding control in heart procedures
This meta-analysis of 30,560 patients undergoing atrial fibrillation ablation found that vascular closure devices (VCDs) significantly reduc…
New data shows that vascular closure devices help stop bleeding faster during atrial fibrillation procedures, though they do not change disc…
Empiric superior vena cava isolation reduces atrial tachyarrhythmia recurrence compared to pulmonary vein isolation alone
Adding a specific step can reduce heart rhythm issues
This meta-analysis of randomized controlled trials evaluated superior vena cava isolation (SVCI) as an adjunct to pulmonary vein isolation (…
Adding a technique called superior vena cava isolation can significantly lower the chances of heart rhythm issues returning after surgery.
Single transseptal puncture is a safe alternative to double puncture for atrial fibrillation ablation
Single Transseptal Puncture Is Safe for Atrial Fibrillation Ablation
This meta-analysis of 1811 patients evaluated single versus double transseptal puncture during atrial fibrillation ablation. The analysis fo…
A single transseptal puncture is a safe alternative to double puncture during atrial fibrillation procedures, despite taking more time to co…
Extended rhythm monitoring identifies 64% of asymptomatic atrial fibrillation in patients on BTKi therapy
BTK Inhibitors Linked to Hidden Heart Rhythm Problem in Cancer Patients
This meta-analysis of 2839 patients with hematologic malignancies treated with Bruton's tyrosine kinase inhibitors (BTKi) found an overall a…
A meta-analysis of 2,839 patients found that 14% of atrial fibrillation cases during BTK inhibitor therapy had no symptoms.
Remote ischemic preconditioning reduces postoperative atrial fibrillation in patients with specific genetic risk factors
Trial Shows Remote Ischemic Preconditioning Reduces Heart Rhythm Issues
Researchers investigated the impact of remote ischemic preconditioning on patients with a specific genetic profile undergoing coronary arter…
A new trial shows that a specific preconditioning technique may reduce the risk of heart rhythm problems after heart bypass surgery.
Intracardiac echocardiography is a safe, non-inferior alternative to transesophageal echocardiography for atrial fibrillation ablation
Intracardiac echocardiography shows safety and efficiency in atrial fibrillation procedures
This meta-analysis of 7,671 patients undergoing catheter ablation for atrial fibrillation found no significant difference between intracardi…
New data shows that intracardiac echocardiography is a safe and effective alternative to traditional imaging during atrial fibrillation hear…
Atrial fibroblast metabolic reprogramming is a candidate mechanism for multicellular atrial cardiomyopathy in atrial fibrillation
Metabolic Changes in Heart Cells May Link to Atrial Fibrillation
This narrative review evaluates atrial fibroblast metabolic reprogramming as a potential mechanism for atrial cardiomyopathy. While studies …
New research explores how changes in cell metabolism might drive heart tissue scarring and irregular heartbeats in conditions like atrial fi…
Questions about Persistent Atrial Fibrillation
Can ethanol infusion during ablation improve rhythm maintenance for patients with persistent atrial fibrillation?
Yes, adding ethanol infusion in the vein of Marshall during ablation improves sinus rhythm maintenance in persistent AF patients, with a 17% absolute benefit at 1 year.
Full answer →What is the success rate for sinus rhythm when adding rotational activity ablation for persistent AF?
Adding rotational activity ablation to standard procedures increases the rate of sinus rhythm maintenance to 91.5% in persistent AF patients, compared to lower rates with standard ablation alone.
Full answer →Does VOM ethanol infusion help keep a normal heart rhythm in persistent atrial fibrillation?
Adding VOM ethanol infusion to standard catheter ablation improves the chance of keeping a normal heart rhythm in persistent atrial fibrillation.
Full answer →