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Rheumatology
RCT
Avacopan Demonstrates Non-Inferiority to Prednisone Taper in Granulomatosis with Polyangiitis and Microscopic Polyangiitis
Trial shows avacopan works as well as prednisone for vasculitis
A Phase 3 trial shows avacopan maintains efficacy comparable to prednisone while significantly reducing glucocorticoid exposure for GPA and …
A new trial shows that patients with specific autoimmune conditions can achieve remission using avacopan instead of tapering off steroid med…
medRxiv
Aug 14, 2026
Rheumatology
Sys. Review
Avacopan is associated with high remission rates and low relapse in ANCA-associated vasculitis
Avacopan shows high remission rates for ANCA-associated vasculitis
This systematic review and meta-analysis of 71 studies indicates that avacopan is associated with an 87% remission rate at 6 months and a 93…
New data shows avacopan helps many patients with ANCA-associated vasculitis reach remission while reducing the need for steroid use.
medRxiv
Jun 18, 2026