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Patient Mode — summaries use plain language, avoiding clinical jargon.
Dermatology
Cohort
Genetic burden in PI3K–AKT–mTOR pathway linked to microscopic polyangiitis susceptibility in Chinese cohort
Genetic markers linked to higher risk of microscopic polyangiitis in Chinese patients
This observational cohort study in a Chinese population examined genetic burden across the PI3K–AKT–mTOR pathway and susceptibility to micro…
A specific genetic load tied to a key cell pathway raises the risk of microscopic polyangiitis, offering new clues for prevention and care.
Frontiers
Apr 24, 2026
Neurology
Cohort
ANCA-associated vasculitis associated with higher mortality and cardiovascular events in retrospective cohort analysis
New data links rare blood vessel diseases to higher death and heart risks.
This retrospective cohort study analyzed 20,422 patients with granulomatosis with polyangiitis and 5,907 with microscopic polyangiitis using…
People with rare blood vessel diseases face nearly three times the death risk and higher heart attack rates compared to healthy people.
Frontiers
Apr 16, 2026
Infectious Disease
Cohort
Japanese AAV Cohort Shows MPA Has 67.6% Five-Year Survival; Glucocorticoid Reduction Not Linked to Better Outcomes
For Japanese patients with a rare autoimmune disease, survival remains challenging.
A retrospective cohort study of 460 treatment-naïve Japanese patients with AAV found microscopic polyangiitis (MPA) had the poorest prognosi…
Japanese patients with microscopic polyangiitis face a five-year survival rate of 67.6%, as older age and kidney issues raise death risk.
Frontiers
Apr 5, 2026