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Home › Conditions › Granulomatosis with polyangiitis

Granulomatosis with polyangiitis

Part of Interstitial Lung Disease

4 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Granulomatosis with polyangiitis

3 trials tracked for Granulomatosis with polyangiitis: 1 in phase 3 or 4.

3Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 4 1 Phase 2 1 Other / NA 1
  1. Phase 4 Pilot Study of Short-Course Glucocorticoids and Rituximab for Treatment of ANCA-Associated Vasculitis Completed
  2. Phase 2 A Phase IIa Study of Intravenous Rituximab in Pediatric Participants With Severe Granulomatosis With Polyangiitis (Wegener's) or Microscopic Polyangiitis Completed
  3. N/A An Observational Study of The Safety of MabThera/Rituxan (Rituximab) in Participants With Granulomatosis With Polyangiitis (Wegener's) or Microscopic Polyangiitis Completed

Showing the 3 most-cited and recently-updated of 3 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Avacopan Demonstrates Non-Inferiority to Prednisone Taper in Granulomatosis with Polyangiitis and Microscopic Polyangiitis
Rheumatology RCT
Avacopan Demonstrates Non-Inferiority to Prednisone Taper in Granulomatosis with Polyangiitis and Microscopic Polyangiitis Trial shows avacopan works as well as prednisone for vasculitis
A Phase 3 trial shows avacopan maintains efficacy comparable to prednisone while significantly reducing glucocorticoid exposure for GPA and …
A new trial shows that patients with specific autoimmune conditions can achieve remission using avacopan instead of tapering off steroid med…
medRxiv Aug 14, 2026
Immunosuppression with corticosteroids and cyclophosphamide leads to clinical improvement in AAV patients with hepatic granulomas
Allergy & Immunology Meta-analysis
Immunosuppression with corticosteroids and cyclophosphamide leads to clinical improvement in AAV patients with hepatic granulomas Treatment shows success for liver issues in specific autoimmune diseases
This systematic scoping review examines the rare manifestation of hepatic granulomatosis in patients with ANCA-associated vasculitides (AAV)…
Patients with rare liver granulomas and certain autoimmune conditions saw improvement when treated with standard immunosuppressive therapies…
Frontiers Jul 23, 2026
Refractory mastoiditis may signal granulomatosis with polyangiitis: case highlights need for early ANCA testing
Allergy & Immunology Sys. Review
Refractory mastoiditis may signal granulomatosis with polyangiitis: case highlights need for early ANCA testing Mastoiditis May Be Linked to Granulomatosis with Polyangiitis
A case report and literature review describes a 69-year-old woman with refractory mastoiditis later diagnosed as granulomatosis with polyang…
A persistent ear infection in an older patient revealed a rare underlying autoimmune condition called granulomatosis with polyangiitis.
Frontiers Jun 29, 2026
ANCA-associated vasculitis associated with higher mortality and cardiovascular events in retrospective cohort analysis
Neurology Cohort
ANCA-associated vasculitis associated with higher mortality and cardiovascular events in retrospective cohort analysis New data links rare blood vessel diseases to higher death and heart risks
This retrospective cohort study analyzed 20,422 patients with granulomatosis with polyangiitis and 5,907 with microscopic polyangiitis using…
People with rare blood vessel diseases face nearly three times the death risk and higher heart attack rates compared to healthy people.
Frontiers Apr 16, 2026

Questions about Granulomatosis with polyangiitis

Are patients with granulomatosis with polyangiitis at higher risk for cardiovascular events?

Patients with granulomatosis with polyangiitis face a significantly higher risk of cardiovascular events like heart attacks and strokes compared to the general population.

Full answer →