Systematic Review Links Lysosomal Pathways to Autoimmune Kidney Disease Progression
Lysosomal pathways may control autoimmune kidney disease progression
This systematic review synthesizes evidence that lysosomal functions act as checkpoints in autoimmune kidney diseases like lupus nephritis a…
New evidence suggests that targeting lysosomal functions could offer a new way to manage serious autoimmune kidney diseases.
ANCA-associated vasculitis associated with higher mortality and cardiovascular events in retrospective cohort analysis
New data links rare blood vessel diseases to higher death and heart risks.
This retrospective cohort study analyzed 20,422 patients with granulomatosis with polyangiitis and 5,907 with microscopic polyangiitis using…
People with rare blood vessel diseases face nearly three times the death risk and higher heart attack rates compared to healthy people.
Japanese AAV Cohort Shows MPA Has 67.6% Five-Year Survival; Glucocorticoid Reduction Not Linked to Better Outcomes
For Japanese patients with a rare autoimmune disease, survival remains challenging.
A retrospective cohort study of 460 treatment-naïve Japanese patients with AAV found microscopic polyangiitis (MPA) had the poorest prognosi…
Japanese patients with microscopic polyangiitis face a five-year survival rate of 67.6%, as older age and kidney issues raise death risk.