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Gastroenterology
Sys. Review
Bismuth quadruple and concomitant regimens achieve >85% H. pylori eradication amid rising clarithromycin resistance
H. pylori treatments failing as resistance grows, review finds
This narrative review synthesizes current H. pylori eradication strategies, noting that clarithromycin resistance exceeds 15%-20% in most re…
Clarithromycin resistance now tops 15-20% in most regions, but bismuth quadruple and other combos still clear the bug over 85% of the time.
Frontiers
Jul 29, 2026
Gastroenterology
RCT
Bismuth quadruple therapy shows higher H. pylori eradication in pediatric patients with clarithromycin resistance
High-Level Clarithromycin Resistance May Predict Bismuth Success in H. pylori
This observational study of 4,610 pediatric patients with H. pylori infection compared bismuth quadruple therapy to triple therapy. Bismuth …
A simple blood test level may predict which H. pylori infections respond best to bismuth therapy, turning a treatment failure sign into a gu…
medRxiv
May 2, 2026
Pediatrics
Cohort
Bismuth-containing quadruple therapy associated with higher H. pylori eradication rates compared to triple therapy in children
New Mix Clears Stomach Bugs Better in Children
This retrospective cohort study of 161 pediatric patients compared 14-day bismuth-containing quadruple therapy against triple therapy for He…
A four-drug plan works better than the usual three-drug plan for clearing stomach bacteria in kids.
Frontiers
Apr 22, 2026