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Infectious Disease
Meta-analysis
Tegoprazan-amoxicillin dual therapy shows no difference in H. pylori eradication compared to bismuth quadruple therapy
Tegoprazan Dual Therapy Shows Similar Success for H. pylori Infection
This meta-analysis of randomized controlled trials involving 1541 participants found that 14-day tegoprazan-amoxicillin dual therapy had no …
A new 14-day dual therapy using tegoprazan and amoxicillin shows similar success rates to standard quadruple therapy for treating H. pylori …
Oct 7, 2026
Infectious Disease
RCT
Minocycline-based regimens are noninferior to bismuth quadruple therapy for refractory H. pylori eradication
New minocycline treatment shows promise for stubborn stomach infections
This randomized controlled trial of 480 participants with refractory H. pylori infection found that three minocycline-containing regimens we…
A new study shows that minocycline-based treatments are as effective as standard options for clearing tough, treatment-resistant stomach inf…
Oct 5, 2026
Infectious Disease
Meta-analysis
Tegoprazan-amoxicillin dual therapy matches quadruple efficacy with fewer adverse events
Tegoprazan dual therapy matches standard H. pylori treatment
This systematic review and meta-analysis with trial sequential analysis compared tegoprazan-amoxicillin (TA) dual therapy with bismuth-conta…
A new review finds a simpler two-drug H. pylori treatment works as well as standard therapy, with fewer side effects.
Aug 4, 2026
Gastroenterology
Sys. Review
Bismuth quadruple and concomitant regimens achieve >85% H. pylori eradication amid rising clarithromycin resistance
H. pylori treatments failing as resistance grows, review finds
This narrative review synthesizes current H. pylori eradication strategies, noting that clarithromycin resistance exceeds 15%-20% in most re…
Clarithromycin resistance now tops 15-20% in most regions, but bismuth quadruple and other combos still clear the bug over 85% of the time.
Frontiers
Jul 29, 2026
Gastroenterology
RCT
Bismuth quadruple therapy shows higher H. pylori eradication in pediatric patients with clarithromycin resistance
High-Level Clarithromycin Resistance May Predict Bismuth Success in H. pylori
This observational study of 4,610 pediatric patients with H. pylori infection compared bismuth quadruple therapy to triple therapy. Bismuth …
A simple blood test level may predict which H. pylori infections respond best to bismuth therapy, turning a treatment failure sign into a gu…
medRxiv
May 2, 2026
Pediatrics
Cohort
Bismuth-containing quadruple therapy associated with higher H. pylori eradication rates compared to triple therapy in children
New Mix Clears Stomach Bugs Better in Children
This retrospective cohort study of 161 pediatric patients compared 14-day bismuth-containing quadruple therapy against triple therapy for He…
A four-drug plan works better than the usual three-drug plan for clearing stomach bacteria in kids.
Frontiers
Apr 22, 2026