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Patient Mode — summaries use plain language, avoiding clinical jargon.
Drug Pipeline
RCT
OnabotulinumtoxinA 72 U reduces masseter prominence versus placebo in adults.
Does this shot really shrink a prominent jaw muscle, or is it just a placebo effect?
This Phase 3, randomized, placebo-controlled trial in 376 adults with Grade 4 or 5 masseter muscle prominence found that onabotulinumtoxinA …
An injection shrinks prominent jaw muscles in over half of adults with severe cases, narrowing the lower face quickly with mostly mild side …
Apr 18, 2026
Drug Pipeline
Phase III
Add-on atogepant 60 mg daily reduced monthly migraine days in chronic migraine patients on stable onabotulinumtoxinA.
Adding atogepant to botulinum toxin reduced migraine days in a small study
This Phase 3, multicenter, 24-week, open-label, single arm study evaluated add-on atogepant 60 mg once daily in 75 participants with chronic…
Adding atogepant to botulinum toxin cut migraine days by over 50% for 62% of patients in a study, with most finding it safe and well-tolerat…
Apr 18, 2026