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Home › Conditions › Masseter muscle prominence

Masseter muscle prominence

1 published article · Updated continuously

Clinical Trial Landscape

Clinical Trials for Masseter muscle prominence

2 trials tracked for Masseter muscle prominence: 1 in phase 3 or 4.

2Trials tracked
1Phase 3 & 4
0Recruiting
0With published results
Phase distribution
Phase 3 1 Phase 2 1
  1. Phase 3 BOTOX® Treatment for Adults With a Wide Lower Face Due to Masseter Muscle Prominence Completed
  2. Phase 2 BOTOX® (onabotulinumtoxinA) Treatment of Masseter Muscle Prominence Completed

Showing the 2 most-cited and recently-updated of 2 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
OnabotulinumtoxinA 72 U reduces masseter prominence versus placebo in adults
Drug Pipeline RCT
OnabotulinumtoxinA 72 U reduces masseter prominence versus placebo in adults Does this shot really shrink a prominent jaw muscle, or is it just a placebo effect?
This Phase 3, randomized, placebo-controlled trial in 376 adults with Grade 4 or 5 masseter muscle prominence found that onabotulinumtoxinA …
An injection shrinks prominent jaw muscles in over half of adults with severe cases, narrowing the lower face quickly with mostly mild side …
Apr 18, 2026