Pharmacological strategies targeting oxidative injury and cell death show potential for intestinal ischemia reperfusion injury
New Pharmacological Strategies Show Potential for Intestinal Ischemia Injury
This narrative review explores pharmacological strategies including thiol compounds, polyphenols, and SIRT-axis modulators for managing inte…
New research identifies several compounds and delivery methods that may help protect the gut during intestinal ischemia and reperfusion inju…
Polyphenols modestly reduce post-exercise soreness, but objective recovery evidence remains uncertain
Polyphenols may slightly reduce muscle pain after intense exercise
This meta-analysis of polyphenol-rich interventions in healthy adults found a small improvement in post-exercise pain/soreness (g = 0.252, 9…
Polyphenol-rich supplements might offer a small boost in reducing muscle soreness after a workout, though evidence for physical recovery is …
Polyphenol supplementation combined with resistance training shows small and statistically uncertain improvements in muscle strength
Polyphenols and Resistance Training Show Uncertain Results for Muscle Growth
This meta-analysis of 360 unique participants examined the effects of polyphenol supplementation combined with resistance training on muscle…
Adding polyphenol supplements to resistance training may have a small effect on strength, but current evidence is not yet clear or certain.
Natural metabolites and their combinations may modulate mitochondrial function and provide cardioprotective effects
Natural Compounds May Support Heart Health via Mitochondrial Regulation
This systematic review explores the role of natural metabolites, including flavonoids, alkaloids, saponins, and polyphenols, in cardiovascul…
Natural compounds like flavonoids and polyphenols may help protect heart cells by improving how mitochondria manage energy and reduce inflam…
Natural compounds may alleviate anesthesia induced cognitive dysfunction through multi-target regulatory mechanisms
Natural Compounds May Help Protect Brains After Anesthesia
This systematic review evaluates 16 natural compounds, including flavonoids and polyphenols, regarding their role in mitigating anesthetic-i…
Certain natural compounds like flavonoids and polyphenols may help protect brain function from damage caused by inhalational anesthetics.
Natural products like polyphenols and berberine modulate gut microbiota to target atherosclerosis pathways
Natural products may target gut health to impact heart disease
This narrative review explores how natural products, including polyphenols and berberine, influence the gut microbiota-metabolite-vascular a…
Certain natural compounds like berberine and polyphenols may help manage atherosclerosis by improving gut health and reducing inflammation.
Antioxidants improve oxidative stress and neuropsychiatric symptoms but not cognition in Alzheimer's
Antioxidants May Improve Neuropsychiatric Symptoms in Alzheimer's Patients
This meta-analysis of 23 RCTs with 10,537 participants found that antioxidants significantly improved urinary 8-iso-prostaglandin F2α (SMD 0…
While antioxidants do not improve memory scores, they may help manage neuropsychiatric symptoms and oxidative stress markers in people with …