HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Rheumatology
Meta-analysis
Vonoprazan reduces delayed bleeding risk in patients with gastric post-endoscopic submucosal dissection ulcers
Vonoprazan may reduce bleeding risk for patients with gastric ulcers
This meta-analysis of 1,136 patients found that vonoprazan significantly reduced the risk of delayed bleeding compared to proton pump inhibi…
A new medication called vonoprazan may lower the risk of bleeding for patients with gastric ulcers compared to standard acid-blocking treatm…
Frontiers
Sep 11, 2026
Rheumatology
Meta-analysis
Endoscopic full-thickness resection resolves abdominal pain in a patient with a gastric diverticulum
Doctors Remove Rare Stomach Pocket That Caused 20 Years of Pain
This case report describes the successful treatment of a 56-year-old woman with a gastric diverticulum using endoscopic full-thickness resec…
A woman who suffered stomach pain after every meal for 20 years finally found relief when doctors removed a rare stomach pocket.
Frontiers
Sep 11, 2026
Oncology
Meta-analysis
PDAC risk prediction models for new-onset diabetes patients show a pooled C-index of 0.78
New Models Predict Pancreatic Cancer Risk in New-Onset Diabetes
This meta-analysis of 14 studies involving 17 prediction models evaluated PDAC risk in patients with new-onset diabetes. The analysis found …
Researchers identified prediction models that can help identify the risk of pancreatic cancer in patients recently diagnosed with new-onset …
Frontiers
Aug 20, 2026
Rheumatology
Guideline
Lifestyle modification and optimized proton pump inhibitor therapy are first-line treatments for gastroesophageal reflux disease
New guidelines offer clearer paths for managing acid reflux disease
This clinical guideline provides standardized management protocols for patients with gastroesophageal reflux disease in Vietnam. It emphasiz…
New clinical guidelines provide a standardized roadmap for diagnosing and treating acid reflux and esophageal inflammation in Vietnam.
Frontiers
Aug 16, 2026
Infectious Disease
RCT
PPI deprescription associated with 3.66 odds of CDI in hospitalized older adults
Stopping certain acid medications might increase risk of stomach infection
This quasi-interventional substudy of a cluster randomized trial involved 4990 hospitalized older adults taking five or more medications. Th…
A study of nearly 5,000 hospitalized seniors found that stopping specific acid-reducing drugs could actually lead to more frequent infection…
medRxiv
Jul 26, 2026
Drug Pipeline
Sys. Review
Narrative review discusses Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis risks from various medications
A review explains which drugs may cause severe skin reactions like Stevens-Johnson Syndrome
This narrative review examines Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis associated with antibiotics, antiepileptics, allopuri…
This review looks at medications linked to rare but dangerous skin conditions. It helps doctors and patients understand the risks.
Frontiers
Jun 2, 2026
Primary Care & Family Medicine
RCT
Patient- and GP-facing deprescribing intervention increases PPI dose reduction by 6.9% in adults with chronic PPI use
Combining patient education with doctor letters cuts acid reflux drug use by nearly 7 percent
This cluster randomized clinical trial evaluated a deprescribing intervention in 1498 general practitioners and 34 409 patients across weste…
A new trial shows that giving patients information and doctors a clear plan helps reduce unnecessary acid reflux medication use in adults.
Jun 1, 2026
Orthopedics & Sports Medicine
Sys. Review
Drug-induced osteoporosis mechanisms and gut microbiota links remain largely unresolved for most medication classes
Many common medicines might change gut bacteria and affect bone strength in older adults
This narrative review examines the association between medications such as glucocorticoids and aromatase inhibitors and gut microbiota alter…
Some drugs like antidepressants and seizure medicines can alter gut bacteria. Scientists are still studying if these changes hurt bones or c…
Frontiers
Jun 1, 2026
Infectious Disease
Sys. Review
Narrative review of vonoprazan for pediatric H. pylori infection
New drug class could simplify hard-to-treat stomach infections in kids
This narrative review synthesizes evidence on vonoprazan-based regimens for Helicobacter pylori infection in pediatric populations. The auth…
A new stomach acid blocker might help clear infections in kids, but doctors need more proof before using it widely.
Frontiers
May 13, 2026
Drug Pipeline
Cohort
Retrospective cohort study links PPI use to drug-related problems in hospitalized renal disease patients
Nearly half of hospitalized kidney patients had drug problems linked to stomach acid reducers
This retrospective cohort study evaluated 520 hospitalized internal nephrology inpatients to assess drug-related problems (DRPs) associated …
Nearly half of hospitalized kidney patients faced drug problems linked to stomach acid reducers. Other medicines and dialysis types also rai…
Frontiers
Apr 30, 2026
Infectious Disease
Meta-analysis
Meta-analysis finds vonoprazan-based therapies achieve 94% H. pylori eradication in Asian populations
The Two-Drug Combo Clearing Stomach Bacteria Where Others Are Failing
A systematic review and meta-analysis of 7,498 Asian patients with Helicobacter pylori infection compared vonoprazan-amoxicillin regimens to…
A new two-drug combo clears stomach bacteria in 94% of Asian patients, outperforming standard treatments where others are failing.
Apr 14, 2026