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Home › Medications › pyrazinamide

pyrazinamide

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of pyrazinamide

13 trials tracked of pyrazinamide: 4 in phase 3 or 4 and 2 with published results. The most-cited published study has 405 citations.

13Trials tracked
4Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 3 4 Phase 2 7 Other / NA 2
  1. Phase 3 The Evaluation of a Standard Treatment Regimen of Anti-tuberculosis Drugs for Patients With MDR-TB Completed · 405 cited
  2. Phase 3 Trial to Evaluate the Efficacy, Safety and Tolerability of BPaMZ in Drug-Sensitive (DS-TB) Adult Patients and Drug-Resistant (DR-TB) Adult Patients Completed · 60 cited
  3. Phase 3 Shortening Treatment by Advancing Novel Drugs Completed
  4. Phase 3 Tuberculosis Treatment Shortening Trial Completed
  5. Phase 2 Treatment Shortening of MDR-TB Using Existing and New Drugs Completed
  6. Phase 2 Evaluation of SQ109, High-dose Rifampicin, and Moxifloxacin in Adults With Smear-positive Pulmonary TB in a MAMS Design Completed
Show 7 more trials
  1. Phase 2 Essentiality of INH in TB Therapy Completed
  2. Phase 2 Assessing PA-824 for Tuberculosis (the APT Trial) Completed
  3. Phase 2 Evaluation of Early Bactericidal Activity in Pulmonary Tuberculosis With(J-M-Pa-Z) (NC-001) Completed
  4. Phase 2 A Phase 2 to Evaluate the Efficacy, Safety and Tolerability of Combinations of Bedaquiline, Moxifloxacin, PA-824 and Pyrazinamide in Adult Subjects With Drug-Sensitive or Multi Drug-Resistant Pulmonary Tuberculosis. Completed
  5. Phase 2 A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis Completed
  6. N/A Fermented Soybean Supplementation Among Active Pulmonary Tuberculosis Patients With Standard Therapy in Indonesia Completed
  7. N/A Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy Completed

Showing the 13 most-cited and recently-updated of 13 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
WGS-based tools provide high specificity and sensitivity for rifampicin, isoniazid, and fluoroquinolone resistance detection
Infectious Disease Meta-analysis
WGS-based tools provide high specificity and sensitivity for rifampicin, isoniazid, and fluoroquinolone resistance detection New tools help doctors identify drug resistant tuberculosis strains
This meta-analysis of 144,623 M. tuberculosis genomes evaluates six open-access WGS-based drug susceptibility testing prediction tools. The …
New computer tools can accurately predict if common drugs will work against tuberculosis, helping doctors choose the right treatment faster.
Aug 12, 2026
Rifapentine 15 mg/kg and 20 mg/kg yield higher culture conversion than standard 6-month regimen
Infectious Disease RCT
Rifapentine 15 mg/kg and 20 mg/kg yield higher culture conversion than standard 6-month regimen Trial Shows Rifapentine Dosage Impacts Tuberculosis Treatment Outcomes
This Phase 2/3 Stage 1 randomized controlled trial of 400 adults with pulmonary drug-susceptible tuberculosis compared three 4-month rifapen…
A new clinical trial explores how different doses of rifapentine affect treatment success and safety for patients with drug-susceptible tube…
Aug 3, 2026
Immediate antituberculosis therapy did not reduce mortality in HIV-related sepsis overall
Infectious Disease RCT
Immediate antituberculosis therapy did not reduce mortality in HIV-related sepsis overall Immediate TB treatment helps only those with confirmed infection in HIV sepsis
This trial investigated whether starting antituberculosis treatment immediately or using high doses improved survival in adults with HIV-rel…
In HIV sepsis, starting TB drugs immediately did not lower death rates overall, but helped only patients later confirmed to have TB.
Jun 1, 2026