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Neurology
Phase III
APOE ε4 carrier status does not accelerate cognitive decline in mild-to-moderate Alzheimer's disease
Genetic markers may relate to Alzheimer's severity but not speed
This observational analysis of the EXPEDITION 1 placebo arm involved 343 patients with mild-to-moderate Alzheimer's disease. The study found…
A new look at Alzheimer's data shows that a specific gene might affect how severe the disease is at first.
medRxiv
Sep 30, 2026
Neurology
Meta-analysis
Meta-analysis finds trivial cognitive effects of amyloid antibodies in mild Alzheimer's disease
Alzheimer’s Drugs Clear Plaques But Don’t Help Memory
This meta-analysis of 17 randomized trials found amyloid-beta-targeting monoclonal antibodies probably have little to no effect on cognitive…
This review shows that even when Alzheimer’s drugs clear amyloid from the brain, patients don’t see meaningful improvements in memory or dai…
Apr 22, 2026