Acute cGAS-STING pathway activation may suppress tumors while chronic activation promotes progression
STING Pathway Activation Shows Mixed Results in Tumor Treatment
This systematic review examines the dual roles of cGAS-STING pathway activation in tumor biology. Findings suggest acute activation promotes…
New research shows that the timing of STING pathway activation may determine whether it helps fight tumors or actually speeds up cancer grow…
Review of STING agonists for high-grade and diffuse midline glioma discusses systemic toxicity and delivery constraints
New Brain Drug Target Could Wake Up the Immune System
This narrative review examines the potential of STING agonists, cyclic dinucleotides, and related compounds for treating high-grade glioma a…
A new brain drug target aims to wake up the immune system's defenses against dangerous, hard-to-treat tumors that hide from the body's natur…