Mode
Home
Research
Clinical Trials Drug Pipeline Weekly Digests
Reference
Conditions Medications
Community
Questions
Text Size
Log in / Sign up
Home › Medications › tenofovir

tenofovir

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials of tenofovir

15 trials tracked of tenofovir: 6 in phase 3 or 4 and 2 with published results. The most-cited published study has 26 citations.

15Trials tracked
6Phase 3 & 4
0Recruiting
2With published results
Phase distribution
Phase 4 2 Phase 3 4 Phase 2 5 Phase 1 2 Other / NA 2
  1. Phase 3 Combination Therapy of Pegylated Interferon Alfa-2a and Tenofovir Versus Tenofovir Monotherapy in Chronic Hepatitis B Completed · 26 cited
  2. Phase 4 The Safety, Pharmacokinetic Profile and Efficacy of Raltegravir in HIV-infected Patients at Least 60 Years of Age Completed · 12 cited
  3. Phase 4 Impact of Menstrual Cycle on Antiretroviral Pharmacokinetics in Healthy Women Completed
  4. Phase 3 Efficacy and Safety Study of Entecavir Plus Tenofovir in Patients With Chronic Hepatitis B Who Failed Previous Treatment Completed
  5. Phase 3 Entecavir Plus Adefovir Combination Therapy Versus Entecavir Monotherapy vs Therapy With Adefovir Plus Lamivudine for Chronic Hepatitis B Infected Subjects With Lamivudine-resistant Virus Completed
  6. Phase 3 Effects of Telbivudine and Tenofovir Disoproxil Fumarate Treatment on the Hepatitis B Virus DNA Kinetics in CHB Completed
Show 9 more trials
  1. Phase 2 Myrcludex B in Combination With Peginterferon Alfa-2a Versus Peginterferon Alfa-2a Alone in Patients With Chronic Viral Hepatitis B With Delta-agent Completed
  2. Phase 2 A Multicenter, Open-label, Randomized Clinical Study to Assess Efficacy and Safety of 3 Doses of Myrcludex B for 24 Weeks in Combination With Tenofovir Compared to Tenofovir Alone to Suppress HBV Replication in Patients With Chronic Hepatitis D Completed
  3. Phase 2 Study to Evaluate a HIV Drug for the Treatment of HIV Infection Completed
  4. Phase 2 Viral Dynamics and Pharmacokinetics of Abacavir and Tenofovir Completed
  5. Phase 2 Elvucitabine/Efavirenz/Tenofovir Versus Lamivudine/Efavirenz/Tenofovir in Human Immunodeficiency Virus (HIV)-1 Infected, Treatment-naive Participants Completed
  6. Phase 1 A Study of Early Immunologic Response in Asian Patients With Chronic Hepatitis B, Treated With Pegasys (Peginterferon Alfa-2a (40KD)), Nucleoside Analogues, or Both Completed
  7. Phase 1 Drug Drug Interaction Study Between BI 201335 and BI 207127 in Chronic Hepatitis C Infected Patients Completed
  8. N/A Comparative Safety Study of Two Vaginal Applicators With Tenofovir Completed
  9. N/A Pharmacokinetic Study of Antiretroviral Drugs and Related Drugs During and After Pregnancy Completed

Showing the 15 most-cited and recently-updated of 15 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
F/TAF PrEP shows similar HIV incidence to F/TDF in cisgender women but noninferiority not proven
Infectious Disease RCT
F/TAF PrEP shows similar HIV incidence to F/TDF in cisgender women but noninferiority not proven PrEP pill F/TAF shows similar HIV prevention as F/TDF in women
This RCT in 1380 predominantly cisgender women in East and South Africa compared daily oral F/TAF vs F/TDF for HIV PrEP over 6 months. HIV i…
A study in African women found that a newer PrEP pill (F/TAF) prevented HIV at similar rates to the standard pill (F/TDF), but the study was…
Jun 1, 2026
Tenofovir Disoproxil Fumarate in Maternal ART Linked to Modest Creatinine Decline in HIV-Positive Women
Infectious Disease RCT
Tenofovir Disoproxil Fumarate in Maternal ART Linked to Modest Creatinine Decline in HIV-Positive Women Women on TDF-based HIV meds showed kidney changes compared to infant-only treatment
This randomized trial compared tenofovir disoproxil fumarate (TDF)-containing maternal antiretroviral therapy (ART) with infant nevirapine p…
Women taking TDF-based HIV meds had larger drops in kidney function than those on infant-only treatment, but calcium and phosphate levels st…
May 1, 2026
CDC updates recommendations for HIV nonoccupational postexposure prophylaxis
Infectious Disease
CDC updates recommendations for HIV nonoccupational postexposure prophylaxis CDC updates recommendations for HIV prevention medication after possible exposure
The CDC has issued updated recommendations for antiretroviral postexposure prophylaxis following nonoccupational HIV exposure.
The CDC updated its guidance on taking HIV prevention medication after a possible exposure to help doctors give the most current advice.
CDC Apr 4, 2026