Living with systemic lupus erythematosus (SLE) already brings many health challenges. New data shows that these patients also face a much higher risk of contracting human papillomavirus (HPV). This virus is a common cause of several types of cancer. Specifically, the study found that the odds of an HPV infection are more than four times higher for people with lupus.
Beyond just the infection, the risk of cancers linked to HPV is substantially elevated for those with lupus. This includes a more than doubled risk of cervical cancer. Even more concerning, the risk for vulvar and vaginal cancers is significantly higher than in the general population.
While these findings highlight a serious link between lupus and these specific cancers, the evidence is still developing. Researchers note that more forward-looking studies are needed to fully understand these risks. For now, these results suggest that doctors should look beyond just cervical screening when monitoring patients with lupus.
What this means for you:
People with lupus have significantly higher risks of HPV infection and related cancers of the cervix, vulva, and vagina.
Common questions
How much higher is the risk of HPV for people with lupus?
The study found that people with systemic lupus erythematosus have significantly increased odds of an HPV infection. Specifically, the odds are more than four times higher compared to the general population. This means the link between lupus and the virus is quite strong.
What specific cancers are linked to lupus and HPV?
Patients with lupus show substantially elevated risks for cancers linked to HPV. This includes a more than doubled risk of cervical cancer. Additionally, there is a much higher risk for cancers of the vulva and vagina.
Is this finding certain for everyone with lupus?
While the data shows a clear link, researchers note that more prospective evidence is needed to fully understand the risks. Because the evidence is still being gathered, you should talk to your doctor about what these findings mean for your specific care.