Follow-up MARCoNS culture status linked to α-MSH levels in chronic inflammatory response syndrome cohort
Chronic Sinus Bacteria Linked to Key Hormone Shift
This retrospective observational cohort study evaluated 188 adult patients with Chronic Inflammatory Response Syndrome.
Clearing stubborn sinus bacteria may help raise a key hormone that regulates pain, inflammation, and energy in people with chronic fatigue.
Higher TyG index associated with increased hyperuricemia prevalence in metabolically healthy participants
Can a simple blood sugar and fat marker predict higher uric acid levels in healthy people?
This cross-sectional study of 1,181 apparently healthy participants with zero metabolic syndrome components found that hyperuricemia prevale…
A simple blood marker combining sugar and fat levels predicts higher uric acid risk in healthy adults, with rates rising from 4% to 11.5% ac…
Retrospective cohort finds COVID-19 infection linked to proteinuria progression in type 2 diabetes
Does COVID-19 worsen kidney issues in people with diabetes?
A retrospective cohort study of 688 patients with type 2 diabetes and COVID-19 versus 502 pre-pandemic uninfected patients with type 2 diabe…
Type 2 diabetes patients fear COVID-19 could worsen kidney stress, raising questions about whether weight or obesity accelerates the risk.
Ex vivo analysis of cytokine and metabolic profiles in placental malaria reveals compartment-dependent T-cell variations
New Immune Pathway Found in Malaria During Pregnancy
This case-control study of 50 women at delivery examined ex vivo cytokine responses and metabolic profiles in placental malaria.
A rare immune cell shift in the placenta may help protect pregnant women and babies from malaria's hidden harms.
Monitoring report on US GLP-1 RA prescribing trends shows increased oral semaglutide use
Why are so many people getting new diabetes and weight-loss drugs?
This monitoring report analyzes real-world US electronic health record data from Truveta on GLP-1 RA prescribing.
Prescriptions for diabetes and weight-loss drugs jumped sharply in the US after a new oral pill was approved, with first-time use rising ove…
Observational study links semaglutide dose and weight loss to lower liver disease risk
Study links semaglutide use to lower risk of several liver conditions in patients with liver disease
This observational study from a real-world federated EHR network analyzed 6,734 patients with liver disease.
Higher semaglutide doses and greater weight loss were linked to lower risks of steatohepatitis, alcoholic liver disease, and death in patien…
NHANES observational review links current smoking to higher HbA1c in non-diabetic adults
Smoking Raises Blood Sugar in People Without Diabetes
This observational analysis of NHANES 2015-2018 data found that current smoking was significantly associated with higher HbA1c among adults …
Quitting smoking may help protect your blood sugar levels, even if you don't have diabetes yet.
Review of UK Biobank data identifies plasma protein mediators in cardiometabolic disease progression
New Blood Test Clues Could Predict Diabetes Complications Years Earlier
This observational review analyzes UK Biobank data from 53,030 participants to evaluate plasma proteins as mediators in secondary disease de…
A new blood test spots specific proteins that warn of heart, kidney, and brain problems years before they happen in people with diabetes or …
Preclinical spatial transcriptomics study maps IMAT gene signature in cardiometabolic disease mouse model
Fat inside your muscles may be rewiring your health—here’s how
This primary preclinical research uses spatial transcriptomics to map human intermuscular adipose tissue (IMAT) gene signatures in a mouse m…
Hidden fat inside your muscles may be rewiring your health by changing how they work, offering new hope for treating metabolic disease.
Narrative review explores CSF1R inhibitor potential in pediatric medulloblastoma precision immunotherapy
The Hidden Reason Children's Brain Tumors Respond So Differently to Treatment
This narrative review examines the role of CSF1R inhibitors as precision immunotherapy for pediatric medulloblastoma subtypes.
Each subtype of children's brain tumors has a unique immune fingerprint, meaning matching treatment to that specific environment could drama…
Weight stigmatization increases physiological stress and appetite markers in women with obesity over 120 minutes
Being Judged for Your Weight Can Change Your Body Chemistry Fast
This randomised feasibility study examined 18 women living with obesity exposed to a weight-stigmatising paradigm versus a non-stigmatising …
Even a brief moment of weight-based judgment may set off a chain of physical stress responses — including hormonal changes that drive hunger…
Cochrane review finds very low-certainty evidence on IGF-1 for ROP in preterm infants
Premature Babies and Eye Disease: A Hopeful Treatment Hits a Wall
This Cochrane systematic review synthesized evidence from two RCTs on IGF-1 for retinopathy of prematurity in preterm infants.
A promising hormone-based treatment for a leading cause of infant blindness has been tested in clinical trials, but the evidence is too thin…