High CALLY index predicts improved survival outcomes in colorectal cancer patients compared to low scores
High CALLY Score Means Better Outlook For Colon Cancer Patients
A meta-analysis of 7,467 colorectal cancer patients reveals that a high CALLY index significantly predicts better overall survival and disea…
A simple blood score called CALLY can tell doctors who will survive longer after colon cancer treatment.
Surgical resection shows superior survival outcomes compared to radiofrequency ablation for small hepatocellular carcinoma cases
Surgery offers better long-term survival and lower recurrence rates for small liver cancer cases compared to ablation
A meta-analysis of 3,551 patients indicates surgical resection offers significantly better long-term survival than radiofrequency ablation f…
A review of 3,551 patients found surgery works better than ablation for small liver tumors. People who had surgery lived longer and had fewe…
Endoscopic submucosal dissection outperforms precut mucosal resection for colorectal polyp removal
Doctors find ESD works better than precut cuts for big polyps
A meta-analysis of 1,460 patients reveals that ESD provides superior en bloc resection compared to EMR-P.
A new review shows endoscopic submucosal dissection removes colorectal polyps more cleanly without adding extra risk to patients.
Bismuth quadruple therapy shows higher H. pylori eradication in pediatric patients with clarithromycin resistance
High-Level Clarithromycin Resistance May Predict Bismuth Success in H. pylori
This observational study of 4,610 pediatric patients with H. pylori infection compared bismuth quadruple therapy to triple therapy. Bismuth …
A simple blood test level may predict which H. pylori infections respond best to bismuth therapy, turning a treatment failure sign into a gu…
Metabolic dysfunction-associated steatotic liver disease patients with advanced fibrosis face high hepatocellular carcinoma risk over ten years
Liver cancer risk much higher with this common condition
A massive meta-analysis of nearly four million individuals reveals stark differences in hepatocellular carcinoma development based on fibros…
Many people with fatty liver disease never know their risk of liver cancer could be rising, especially if they have undetected scarring.
Text reminders and letters increased FIT completion in overdue colorectal cancer screening patients
Text reminders and letters boost colorectal cancer screening completion in primary care
This randomized trial evaluated screening completion in primary care patients aged 50 to 74 years who were overdue for colorectal cancer scr…
Text messages and reminder letters significantly increased colorectal cancer screening completion, while a branded box did not improve rates…
TaTME shows lower conversion rates with similar short-term safety compared to LapTME for low rectal cancer
New surgical approach for rectal cancer cuts conversion rate
This randomized trial compared transanal total mesorectal excision with laparoscopic total mesorectal excision for patients with low rectal …
A new surgical technique for rectal cancer reduces the need to switch to open surgery, with similar complication rates.
Meta-analysis of placebo responses in metabolic dysfunction-associated steatohepatitis trials reveals modest natural resolution rates and low progression risk
New meta-analysis shows how many patients improve on placebo for MASH
This systematic review and meta-analysis examined placebo outcomes in patients with metabolic dysfunction-associated steatohepatitis.
This analysis of 6,880 patients reveals natural improvement rates in metabolic dysfunction-associated steatohepatitis when no active drug is…
Avelumab plus cetuximab versus cetuximab alone in metastatic colorectal cancer patients
Adding avelumab to cetuximab helps only a specific subgroup of colorectal cancer patients
This randomized phase II trial evaluated adding avelumab to cetuximab in RAS/BRAF wild-type metastatic colorectal cancer patients.
A new trial shows adding avelumab to cetuximab improves survival only for patients without certain genetic changes, not for everyone.
Systematic review and meta-analysis assesses SWDS diagnostic accuracy for MASLD liver inflammation grading
Shear-wave dispersion slope helps doctors grade liver inflammation in metabolic disease
This systematic review and diagnostic test accuracy meta-analysis evaluates the Shear-wave dispersion slope (SWDS) for detecting and grading…
A new analysis shows a noninvasive test can accurately detect and grade liver inflammation in patients with metabolic dysfunction-associated…
Educational programs improve self-care values in ostomized colorectal cancer patients
Educational programs boost self-care values in ostomized colorectal cancer patients
This systematic review analyzed educational intervention programs for ostomized colorectal cancer patients.
A meta-analysis of 1,011 patients found educational programs significantly improve self-care values compared to no intervention.
Zibotentan plus dapagliflozin shows no HVPG reduction in compensated cirrhosis
Early trial shows zibotentan plus dapagliflozin trended toward lowering blood pressure in cirrhosis patients
This Phase II randomized placebo-controlled exploratory study in 28 patients with compensated cirrhosis found that zibotentan 2.5 mg plus da…
An early study found that a combination drug lowered blood pressure in patients with compensated cirrhosis, though it did not conclusively i…