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Oncology

1102 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Perioperative nursing training protocol improves satisfaction in implant-based breast reconstruction
Oncology Sys. Review
Perioperative nursing training protocol improves satisfaction in implant-based breast reconstruction Specialized Nursing Training Improves Satisfaction in Breast Reconstruction Patients
This quasi-experimental study of 82 patients undergoing implant-based breast reconstruction found that a perioperative nursing protocol supp…
A new nursing training program may improve patient satisfaction with surgical outcomes and care during breast reconstruction.
Multi-component health system interventions improve access to external beam radiotherapy in low and middle income countries
Oncology Sys. Review
Multi-component health system interventions improve access to external beam radiotherapy in low and middle income countries Health System Changes Improve Access to Radiation Therapy
This scoping review of 31 studies examines health system interventions to improve external beam radiotherapy (EBRT) access. Findings suggest…
New research shows that improving infrastructure and training can help more patients get life-saving radiation treatment in underserved area…
Transbronchial biopsy with 1.1-mm cryoprobe yields 88.6% diagnosis versus 78.8% with 2.0-mm forceps
Oncology RCT
Transbronchial biopsy with 1.1-mm cryoprobe yields 88.6% diagnosis versus 78.8% with 2.0-mm forceps Cryoprobe biopsy shows higher success rate for diagnosing lung conditions
This randomized clinical trial of 500 patients across 9 US centers compared a 1.1-mm cryoprobe to 2.0-mm forceps for transbronchial biopsy. …
A new cryoprobe tool may provide more accurate diagnoses for lung nodules and transplant issues while reducing the risk of certain complicat…
Longitudinal ctDNA analysis identifies AR gene alterations and extrachromosomal DNA as features of resistance
Oncology Phase III
Longitudinal ctDNA analysis identifies AR gene alterations and extrachromosomal DNA as features of resistance Blood tests may track how prostate cancer resists treatment
This observational study of 327 patients with metastatic castration-resistant prostate cancer (mCRPC) utilized longitudinal ctDNA analysis t…
New research shows that tracking DNA in the blood can help identify specific genetic changes when prostate cancer stops responding to therap…
Polycystic Ovary Syndrome associated with higher neonatal jaundice rates in Gestational Diabetes Mellitus
Oncology RCT
Polycystic Ovary Syndrome associated with higher neonatal jaundice rates in Gestational Diabetes Mellitus Women with PCOS face higher rates of infant jaundice during pregnancy
This secondary analysis of a randomized controlled trial involving 425 pregnant women with Gestational Diabetes Mellitus and BMI ≥25 kg/m² f…
A new look at pregnancy data shows that babies born to mothers with Polycystic Ovary Syndrome have higher rates of jaundice.
Fissios App plus physiotherapy aims to cut postoperative complications in NSCLC surgery
Oncology RCT
Fissios App plus physiotherapy aims to cut postoperative complications in NSCLC surgery App may help lung cancer patients avoid complications after surgery
This randomized controlled trial protocol will enroll 560 NSCLC patients scheduled for surgery to test whether adding the Fissios App to fac…
A new trial will test if an app can help lung cancer patients avoid complications after surgery. Here's what's planned.
Symptomatic radiation necrosis occurs in 5.7% of intracranial brachytherapy patients
Oncology Meta-analysis
Symptomatic radiation necrosis occurs in 5.7% of intracranial brachytherapy patients Brachytherapy for brain tumors: 5.7% risk of radiation necrosis
This meta-analysis of 3666 patients undergoing intracranial brachytherapy for glioma, brain metastases, or meningioma found a pooled inciden…
About 1 in 18 patients who get internal radiation for brain tumors develop symptomatic radiation necrosis, a new analysis finds.
Serplulimab plus chemotherapy improves overall survival compared to chemotherapy alone in nsq-NSCLC
Oncology RCT
Serplulimab plus chemotherapy improves overall survival compared to chemotherapy alone in nsq-NSCLC Trial shows serplulimab improves survival in certain lung cancers
This Phase III randomized controlled trial of 636 treatment-naïve patients with locally advanced or metastatic nsq-NSCLC found that serpluli…
A new clinical trial shows that adding serplulimab to chemotherapy can extend life for patients with specific types of non-small cell lung c…
I-SPECT/CT shows high patient-level specificity of 0.95 for detecting residual disease in DTC
Oncology Meta-analysis
I-SPECT/CT shows high patient-level specificity of 0.95 for detecting residual disease in DTC Imaging technology shows promise for detecting thyroid cancer recurrence
This meta-analysis evaluates the diagnostic efficacy of I-SPECT/CT for identifying residual or recurrent disease in patients with differenti…
A new imaging method called I-SPECT/CT helps doctors find leftover or returning thyroid cancer cells with high accuracy after treatment.
Evaluating ctDNA Dynamics as Prognostic Biomarkers in Advanced HR+ HER2- Breast Cancer
Oncology Phase III
Evaluating ctDNA Dynamics as Prognostic Biomarkers in Advanced HR+ HER2- Breast Cancer Ribociclib and Letrozole Show Promise for Advanced Breast Cancer
This Phase IIIb trial evaluates how circulating tumor DNA (ctDNA) dynamics influence progression-free survival for patients treated with rib…
New data suggests that tracking specific genetic markers in the blood may help predict how well patients with advanced breast cancer respond…
DeSTIL-positive HER2+ breast cancer patients show HR 0.09 for event-free survival with trastuzumab
Oncology RCT
DeSTIL-positive HER2+ breast cancer patients show HR 0.09 for event-free survival with trastuzumab Trial Shows DeSTIL Signature Identifies Patients Benefiting From Trastuzumab
This Phase III randomized clinical trial evaluated the DeSTIL signature in a cohort of 221 validation patients and 250 training patients wit…
A new genetic marker called DeSTIL helps identify which HER2-positive breast cancer patients may see better outcomes when treated with trast…
Immunohistochemical profiling helps differentiate synchronous primary breast invasive carcinoma from metastatic ovarian carcinoma
Oncology Sys. Review
Immunohistochemical profiling helps differentiate synchronous primary breast invasive carcinoma from metastatic ovarian carcinoma One woman diagnosed with two different types of cancer simultaneously
This case report and literature review describes a patient with concurrent primary breast cancer and metastatic high-grade serous ovarian ca…
A rare case reveals how one patient can have both breast and ovarian cancer at once, highlighting a complex diagnostic challenge.