Sulforaphane may modulate tumor suppressor genes and reduce Ki-67 proliferation index in specific cohorts
Sulforaphane Shows Potential in Research on Cancer Cell Growth
This systematic review of 118 studies including clinical trials, observational studies, and preclinical investigations explores the role of …
A review of 118 studies suggests that sulforaphane may slow certain cancer cell markers and could inform future ways to prevent cancer.
Electronic monitoring questionnaires did not significantly change time to pharmacist intervention in intent-to-treat analysis
Electronic Monitoring May Help Manage Side Effects of Anticancer Drugs
This randomized controlled trial of 388 patients on oral anticancer therapy found no significant difference in time to pharmacist interventi…
New research explores how electronic monitoring questionnaires can help patients manage side effects and reduce healthcare use during cancer…
IL-37 and IL-38 act as endogenous regulators of CAR-T-associated hyperinflammation in multiple myeloma
New Proteins May Help Control Inflammation in Multiple Myeloma Treatment
This mini-review explores the roles of IL-37 and IL-38 as potential immunoregulatory checkpoints in patients with relapsed/refractory multip…
Two specific proteins, IL-37 and IL-38, may help control dangerous inflammation during CAR-T cell therapy for multiple myeloma.
Necrotic alterations in paragangliomas are associated with higher metastasis rates and cardiovascular complications
Necrotic Alterations Linked to Higher Metastasis in Paragangliomas
This meta-analysis and retrospective study evaluate the clinical implications of necrotic versus cystic alterations in patients with confirm…
Research shows that tumors with necrotic tissue are linked to higher metastasis rates and more cardiovascular complications in patients with…
Exposome-informed multi-omics and AI may enable precision prevention in diffuse glioma, but screening not yet justified
AI and Exposome Data May Sharpen Glioma Risk Tools
This systematic review synthesizes evidence on integrating exposome-informed multi-omics and artificial intelligence in diffuse glioma resea…
Combining environmental exposure data with AI could improve glioma monitoring, but population-wide screening isn't ready yet.
Post-radiotherapy dental extractions increase odds of osteoradionecrosis by 8.38 in head and neck cancer patients
Specific Risk Factors Linked to Jaw Damage After Radiation Therapy
This meta-analysis of 10 studies identifies several risk factors for osteoradionecrosis of the jaws (ORNJ) in patients undergoing head and n…
Certain factors like smoking and dental extractions after radiation are linked to a higher risk of jaw bone damage in head and neck cancer p…
Comparative Efficacy of Robot Assisted Radical Nephrectomy and Open Surgery for IVC Thrombus
Robot assisted surgery shows fewer complications for certain kidney cancers
Meta-analysis indicates robot-assisted radical nephrectomy reduces blood loss, transfusion needs, and major complications in patients with r…
Robotic surgery may reduce blood loss and hospital stays for patients with specific types of kidney cancer involving the inferior vena cava.
Adjunctive hemostatic agents in partial nephrectomy show no transfusion benefit
Adding topical agents to kidney surgery does not reduce blood loss
This meta-analysis of 3408 patients undergoing partial nephrectomy for T1 renal tumors found no significant difference in blood transfusion …
New data shows that adding certain clotting agents during kidney surgery does not lower the need for blood transfusions or prevent complicat…
CXRT improves survival and disease-free rates specifically in node-negative pancreatic head adenocarcinoma patients
Radiotherapy shows promise for specific pancreatic cancer patients
This Phase III multicenter randomized controlled trial of 354 patients with adenocarcinoma of the pancreatic head found no significant diffe…
Adding radiation to chemotherapy may improve survival and stay disease-free for certain patients with pancreatic head cancer.
Virtual sustained treatment increases 6-month abstinence rates to 28.4% compared to 14.7% in cancer patients
Virtual counseling and nicotine therapy help cancer patients quit smoking
This randomized controlled trial of 306 English- and Spanish-speaking cancer patients found that virtual sustained treatment (VST) significa…
A new trial shows that virtual coaching combined with nicotine replacement helps significantly more cancer patients quit smoking than standa…
Primary pulmonary Ewing sarcoma should be considered in non-smoking patients with hemoptysis or back pain
New cases help identify rare lung cancer in specific patients
This case report and literature review describes 2 cases of primary pulmonary Ewing sarcoma (PES). The authors argue that PES should be incl…
Doctors identified a rare type of lung cancer in two patients, highlighting how different symptoms can point toward this specific diagnosis.
R.E.N.A.L., PADUA, and (MC)2 scoring systems correlate with increased complication risks in renal tumor ablation
Scoring systems help predict complications after renal tumor ablation
This meta-analysis of 25 retrospective studies evaluates the R.E.N.A.L., PADUA, and (MC)2 scoring systems for predicting complications follo…
New analysis shows that specific scoring systems can help doctors predict and manage risks for patients undergoing surgery to remove kidney …