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Ophthalmology

102 published articles · Updated continuously

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Systematic review of extensive macular atrophy with pseudodrusen reports visual acuity decline and atrophy progression
Ophthalmology Meta-analysis
Systematic review of extensive macular atrophy with pseudodrusen reports visual acuity decline and atrophy progression Eye disease linked to vision loss and thicker eye layers in study
This systematic review and meta-analysis of 1096 eyes with extensive macular atrophy with pseudodrusen (EMAP) found a mean visual acuity dec…
A review of over 1,000 eyes shows EMAP leads to significant vision loss and thicker eye layers over time.
Obstructive Sleep Apnea Associated with Higher Odds of Age-Related Macular Degeneration
Ophthalmology Meta-analysis
Obstructive Sleep Apnea Associated with Higher Odds of Age-Related Macular Degeneration Large study links obstructive sleep apnea to higher risk of age-related macular degeneration
A systematic review and meta-analysis of 3,536,314 adults found that obstructive sleep apnea (OSA) was associated with higher odds of age-re…
A massive analysis of over 3.5 million people suggests obstructive sleep apnea is linked to a higher risk of age-related macular degeneratio…
Systematic review and meta-analysis shows aflibercept biosimilars match reference drug efficacy and safety in AMD and DME
Ophthalmology Meta-analysis
Systematic review and meta-analysis shows aflibercept biosimilars match reference drug efficacy and safety in AMD and DME Aflibercept biosimilars match the original drug for eye disease treatment
This systematic review and meta-analysis evaluated aflibercept biosimilars versus reference aflibercept for neovascular age-related macular …
A large review of 4064 patients found that aflibercept biosimilars work just as well as the original drug for two common eye conditions.
Meta-analysis of tafluprost-timolol fixed-dose combination for open-angle glaucoma and ocular hypertension
Ophthalmology Meta-analysis
Meta-analysis of tafluprost-timolol fixed-dose combination for open-angle glaucoma and ocular hypertension Tafluprost-timolol drops lower eye pressure than switching to single drugs
This meta-analysis evaluated the tafluprost-timolol fixed-dose combination versus a monotherapy switch group in patients with open-angle gla…
A meta-analysis of 2066 patients found that fixed-dose tafluprost-timolol lowered eye pressure more than switching to monotherapy, with mini…
AI-based fluid volume quantification predicts visual acuity in neovascular AMD better than CST
Ophthalmology RCT
AI-based fluid volume quantification predicts visual acuity in neovascular AMD better than CST AI fluid measurements better predict vision loss than thickness in AMD
This randomized phase III trial in 290 eyes with neovascular AMD found that AI-based quantification of intraretinal and subretinal fluid vol…
AI-based fluid volume tracking explains more vision changes than standard thickness measurements in macular degeneration patients.
Aflibercept 8 mg extended dosing maintains visual gains with fewer injections versus 2 mg every 8 weeks in DME
Ophthalmology RCT
Aflibercept 8 mg extended dosing maintains visual gains with fewer injections versus 2 mg every 8 weeks in DME Aflibercept 8 mg every 16 weeks matches standard dosing for diabetic macular edema
This randomized, double-masked, noninferiority phase 2/3 trial enrolled 658 patients aged ≥ 18 years with center-involved diabetic macular e…
A new trial shows that aflibercept 8 mg every 16 weeks works as well as the standard 2 mg every 8 weeks for diabetic macular edema with fewe…
Mingmu Dihuang Tang plus conventional treatment improved visual acuity and reduced complications in elderly cataract patients
Ophthalmology RCT
Mingmu Dihuang Tang plus conventional treatment improved visual acuity and reduced complications in elderly cataract patients Trial shows Mingmu Dihuang Tang plus Western medicine improves cataract markers
This randomized controlled trial enrolled 120 elderly patients with cataract.
Adding Mingmu Dihuang Tang to standard care improved antioxidant levels and vision recovery in elderly patients with cataracts.
Systematic review and meta-analysis links pregnancy to higher risk of central serous chorioretinopathy
Ophthalmology Meta-analysis
Systematic review and meta-analysis links pregnancy to higher risk of central serous chorioretinopathy Pregnancy increases risk of central serous chorioretinopathy by more than five times
This systematic review and meta-analysis evaluates the association between pregnancy and central serous chorioretinopathy (CSC) using data f…
A large review found pregnancy raises the risk of central serous chorioretinopathy significantly. This matters for expectant mothers and doc…
Systematic review and meta-analysis of uveitis subtypes in European tertiary centers
Ophthalmology Meta-analysis
Systematic review and meta-analysis of uveitis subtypes in European tertiary centers European data show most adult uveitis cases are anterior or non-infectious
This systematic review and meta-analysis of 30 471 patients from European tertiary centers found that anterior uveitis is the most common su…
A large review of 30,471 patients found that over half of uveitis cases were anterior and nearly half were non-infectious across Europe.
Motivational Interviewing Workshop Improves Communication Skills in Ophthalmology Residents
Ophthalmology RCT
Motivational Interviewing Workshop Improves Communication Skills in Ophthalmology Residents Motivational Interviewing Workshop Boosts Glaucoma Counseling Skills
This pilot RCT with 20 ophthalmology residents found that a 1-hour Motivational Interviewing workshop improved standardized patient encounte…
A simple one-hour class helps doctors talk to glaucoma patients in ways that actually change behavior and improve medication use.
Brolucizumab Protocol for Chronic Central Serous Chorioretinopathy Compared to Multivitamins
Ophthalmology RCT
Brolucizumab Protocol for Chronic Central Serous Chorioretinopathy Compared to Multivitamins Doctors test new eye drug for stubborn fluid without neovascularization
This protocol describes a randomized controlled trial comparing intravitreal brolucizumab to oral multivitamins in 42 patients with chronic …
A new eye drug trial could help people with stubborn fluid in their retina by comparing it to vitamins in a strict study.
Systematic review and meta-analysis of intra-arterial chemotherapy for pediatric retinoblastoma outcomes
Ophthalmology Meta-analysis
Systematic review and meta-analysis of intra-arterial chemotherapy for pediatric retinoblastoma outcomes Meta-analysis links intra-arterial chemotherapy to better outcomes for pediatric retinoblastoma
This systematic review and meta-analysis evaluated intra-arterial chemotherapy (IAC) versus intravenous chemotherapy (IVC) for pediatric ret…
A meta-analysis of twelve studies suggests intra-arterial chemotherapy improves survival and eye salvage compared to intravenous chemotherap…