Hematocrit–albumin gap linked to sepsis risk in ICU adults in retrospective analysis
Does a simple blood number predict sepsis risk in ICU patients?
A retrospective cross-sectional analysis of 19,134 adults with first ICU admissions found that a higher hematocrit–albumin gap (HAG) was ass…
A simple blood number called the hematocrit–albumin gap predicts sepsis risk in ICU patients, with higher levels increasing infection odds b…
Structured pain assessment in post-mastectomy pain syndrome links mixed pain to multiple sources and radiotherapy
The Hidden Pain Pattern Affecting One in Three Breast Cancer Survivors
A retrospective cohort analysis of 120 women with refractory post-mastectomy pain syndrome at a tertiary clinic found that mixed pain phenot…
About one-third of breast cancer survivors have mixed pain after surgery, and radiation or multiple pain sources make it much more likely.
Protocol outlines individualized anticoagulation monitoring in critically ill adults using unfractionated or low-molecular-weight heparin
ICU Blood Clot Prevention Has a Monitoring Problem — This Study Aims to Fix It
This study protocol describes a prospective observational cohort design evaluating individualized anticoagulation monitoring in critically i…
A new prospective study is testing whether a real-time clotting test called viscoelastic testing can give ICU doctors a more complete pictur…
POEM in Allgrove syndrome shows earlier symptom onset and favorable outcomes versus idiopathic achalasia
New Hope for Rare Childhood Disorder Affecting Eating
This cohort study from Peking Union Medical College Hospital, China, compared peroral endoscopic myotomy (POEM) outcomes in 7 patients with …
A minimally invasive procedure now helps children with rare Allgrove syndrome eat without pain, offering long-term relief for those who once…
PPI-refractory GERD prevalence and mechanisms in systemic sclerosis using ambulatory pH-MII, HREM, and scintigraphy
Heartburn Pills Often Fail in Scleroderma—New Study Reveals Why
This retrospective cohort study of 30 adults with systemic sclerosis evaluated PPI-refractory GERD using ambulatory pH-MII, HREM, and gastri…
Standard heartburn pills often fail for scleroderma patients because weak muscle movement in the esophagus and stomach prevents acid from cl…
GATT reduces IOP in normal-tension glaucoma patients over 24 months
GATT Surgery Lowers Eye Pressure for Years
This single-center retrospective case series evaluated gonioscopy-assisted transluminal trabeculotomy (GATT) in 9 patients with normal-tensi…
GATT surgery lowered eye pressure by an average of 4 mmHg for two years in patients with normal-tension glaucoma, offering a long-term alter…
Study protocol outlines randomized trial of 40 Hz auditory stimulation for postoperative sleep disturbance
Could quiet headphones help patients sleep better after gynecological surgery?
This document describes a protocol for a randomized controlled trial involving 342 patients scheduled for laparoscopic gynecological surgery…
A new trial will test if playing a 40 Hz sound during gynecological surgery helps patients sleep better the first night after the operation.
Extended reality head-mounted displays show mixed knowledge gains and high satisfaction in US medical and nursing education
VR Headsets Are Reshaping How Future Doctors Learn
This systematic review analyzed 29 U.S.-based studies evaluating extended reality head-mounted displays (XRHMD) against traditional methods …
Virtual reality headsets are quietly moving into U.S. medical schools to help students practice complex procedures in immersive 3D simulatio…
Systematic review examines IL-35 and IL-39 roles in rheumatoid arthritis pathophysiology and therapeutic potential
Two Hidden Signals May Explain Rheumatoid Arthritis Flares
This mini-review synthesizes available evidence regarding IL-35 and IL-39 in rheumatoid arthritis.
Two tiny immune signals fighting each other may hold the key to calming rheumatoid arthritis at its source.
Acupuncture plus embryo transfer increases clinical pregnancy rates in recurrent implantation failure patients
Tiny Needles May Boost IVF Success After Repeat Failures
A meta-analysis of randomized controlled trials involving 1,428 patients with recurrent implantation failure evaluated acupuncture combined …
Adding acupuncture around embryo transfer raised pregnancy rates by 73% for women facing repeated IVF failures, offering new hope after mult…
Whole-exome sequencing identifies chronic pancreatitis as a phenotype in 17q12 deletion syndrome
A Rare Genetic Condition Just Got a Newly Recognized Symptom
A systematic review of a single case report involving an 18-year-old female with 17q12 deletion syndrome utilized whole-exome sequencing.
An 18-year-old's mysterious abdominal pain turned out to be linked to a rare genetic syndrome — and her case may help doctors recognize this…
Pemetrexed use associated with disproportionate reporting of blood, endocrine, and renal disorders in FAERS data
Your Lung Cancer Drug May Have Side Effects Not on the Label
This pharmacovigilance study analyzed 27,098 pemetrexed-associated reports in the US FAERS database from 2004 to 2024.
A safety review of over 27,000 reports found that the lung cancer drug pemetrexed may cause side effects not currently listed on its officia…