N/A N=164 Extracardiac Complications After Cardiac Surgery
Acute Lung Injury · Sepsis · Infections
Primary: Acute Lung Injury After Cardiac Surgery — 20 participants — p=<0.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=6 Extracorporeal Membrane Oxygenation (ECMO) in Non-intubated Patients With Acute Respiratory Distress Syndrome (ARDS)
ARDS
Primary: Number of Participants That Did Not Require Endotrachael Intubation — 3 participants
N/A N=4 Leg Exercise During ECMO
Refractory Respiratory Failure
Primary: Time to Ambulation — 14.5; 15 days
N/A N=24 Markers of Inflammation and Lung Recovery in ECMO Patients for PPHN
Persistent Pulmonary Hypertension of the Newborn
Primary: CD16/41 — 1.90; 1.13 percent change
N/A N=20 Pharmacokinetic Alterations During ECMO
Acute Respiratory Failure
Primary: Cumulative Fentanyl Equivalents From ECMO Initiation to Decision to Achieve Wakefulness — 330; 834 mg
N/A N=50 Extracorporeal Lung Assist to Avoid Intubation in Patients Failing Noninvasive Ventilation for Hypercapnic ARF
Hypercapnia · Respiratory Insufficiency
Primary: Number of Patients With Need for Intubation for Invasive Mechanical Ventilation — 11; 25 Participants
N/A N=26 Strategies for Anticoagulation During Venovenous ECMO
Acute Hypoxemic Respiratory Failure · Anticoagulant-induced Bleeding · Thromboembolism
Primary: Number of Participants With Major Bleeding Events — 1; 4 Participants
N/A N=1,705 ED Lung Protective Ventilation to Reduce Complications
Mechanical Ventilation · Ventilator-associated Conditions · ARDS
Primary: Number of Patients That Experience Pulmonary Complications After Admission From the Emergency Department — 171; 38 participants
Phase 1 N=8 Imipenem/Cilastatin/Relebactam PK in ECMO
Sepsis
Primary: Imipenem Clearance — 15.21 Liters per hour
N/A N=31 The Effect of Prophylactic FFP Administration on ECMO Circuit Longevity
Extracorporeal Membrane Oxygenation
Primary: ECMO Pump Longevity — 187; 131 hours — p=0.39
N/A N=15 ECPR for Refractory Out-Of-Hospital Cardiac Arrest
Cardiac Arrest · Heart Arrest · Sudden Cardiac Arrest
Primary: Emergency Department Arrivals Under 30 Minutes — 5 Participants
N/A N=219 Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study
Respiratory Failure · Mechanical Ventilation · Acute Lung Injury
Primary: To Further Characterize ED Mechanical Ventilation — 500 mL
N/A N=18 Renal Perfusion, Filtration and Oxygenation During Cardiopulmonary Bypass (CPB)
Complication of Extracorporeal Circulation · Renal Impairment
Primary: Renal Blood Flow (RBF) — 554; 524; 564; 558 ml per minute per 1.73 m2 body surface — p=0.638
Phase 4 N=50 ECMO Hemostatic Transfusions in Children
Extracorporeal Membrane Oxygenation Complication · Hemorrhage · Thromboembolism
Primary: Total Platelet Transfusion Dose — 7.4; 0 mL/kg/day
N/A N=14 Modified Perfusion for Neonatal Aortic Arch Reconstruction
Aortic Arch Hypoplasia or Atresia
Primary: Intestinal Fatty Acid Binding Protein and C-reactive Protein
Phase 4 N=129 Non Invasive Mechanical Ventilation in Acute Cardiogenic Pulmonary Edema
Acute Cardiogenic Pulmonary Edema
Primary: Number of Patients Who Were Intubated — 5; 4; 10 participants
N/A N=16 Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome · ARDS
Primary: Mechanical Power — 1.87; -2.50 J/min — p=.002
N/A N=320 Intensive Alveolar Recruitment Protocol After Cardiac Surgery
Ventilator Induced Lung Injury · Cardiac Disease · Acute Lung Injury
Primary: Severity of Pulmonary Complications in the Post-operative Period — 15; 26 percentage of participants — p=0.016
N/A N=245 Tissue Oxygenation During Treatment of Infant Congenital Heart Defects
Acute Kidney Injury · Hypoxia-Ischemia, Brain · Mesenteric Ischemia
Primary: Number of Participants With Acute Kidney Injury — 18; 57 Participants
Phase 4 N=15 Pharmacokinetics of Tamiflu® (Oseltamivir) in Patients Receiving Extracorporeal Membrane Oxygenation (ECMO)and or Continuous Venovenous Hemodialysis (CVVHD)
Critically Ill Renal Failure Requiring CVVHD and Oseltamivir · Critically Ill Requiring ECMO and Oseltamivir
Primary: Continuous Venovenous Hemodialysis (CVVHD)Oseltamivir Carboxylate Transmembrane Clearance — 52.2; 43.3 mL/min
N/A N=104 Does MiECC Improve Outcome in Diabetic Patients Undergoing Elective Coronary Bypass Grafting?
Acute Kidney Injury
Primary: Acute Kidney Injury — 7; 41; 9; 40 participants — p=0.377
N/A N=32 CentriMag Ventricular Assist System in Treating Failure-to-Wean From Cardiopulmonary Bypass
Heart Failure
Primary: Survival — 20 Participants
N/A N=2 Bidirectional Oxygenation Valve in the Management of Pulmonary Complications of COVID-19
COVID-19
Primary: Oxygen Saturation by Pulse Oximetry — 92; 93.5; 94; 94 percentage of oxygen saturation
N/A N=78 AMBU Bag Manual Ventilation vs. Transport Ventilator Mechanical Ventilation for Transport
Oxygenation · Manual Ventilation · Mechanical Ventilation
Primary: The % Change in Mean Artery Blood Pressure — -3.73; 13 % change in mean artery pressure
N/A N=5 Pre-hospital ECMO in Advanced Resuscitation in Patients With Refractory Cardiac Arrest. ( SUB30 )
Death, Sudden, Cardiac · Out-Of-Hospital Cardiac Arrest · Ventricular Fibrillation
Primary: Proportion of Patients Successfully Established With Pre-hospital ECPR — 0 Participants
Phase 3 N=46 Cytokine Removal in Cardiopulmonary Bypass Patients
Elective Cardiac Surgical Interventions
Primary: IL-6 — 0; 0; 0; 0 pg/ml
N/A N=5 Safety and Performance of the COR-VG-001 Conduit in Pediatric Patients for Extracardiac Total Cavopulmonary Connection
Heart Defects, Congenital
Primary: The Number of Graft Related Post-operative Complications That Require a Repeat Surgery or a Non Surgical Treatment Within 12-month Post Implantation. — 0 Participants
N/A N=10 Blood Volume and Fluid Kinetics in Patients Undergoing Extracorporal Circulation
Blood Volume, Extravasation
Primary: Blood Volume — 4.61 Litre
Phase 2 N=171 Point-of-Care RBC Washing to Prevent Transfusion-Related Pulmonary Complications
Blood Transfusion Complications
Primary: Biomarkers Associated With Transfusion-Related Acute Lung Injury and Transfusion Associated Circulatory Overload. — 101; 105; 12; 15 units on a scale (pg/ml)
N/A N=65 Ventilator-induced Lung Injury Vortex in Patients With SARS-CoV-2
ARDS · Mechanical Ventilation Complication · Ventilator-Induced Lung Injury
Primary: Number of Participants Who Survived and Died — 1; 31; 14; 19 Participants