N/A N=40 Mindfulness for Resilience in Early Life
Adolescent With Early Life Stress · Resilience
Primary: Cortisol Reactivity — -0.21; 0.34; 0.05; -0.08 μg/dL — p=<.05
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=40 Depression, Epinephrine, and Platelet Function
Major Depressive Disorder
Primary: Response of Participants, Defined by Change in the 21-item Hamilton Depression Rating Scale (HDRS) From Baseline to Week8 — 5; 9; 2; 4 participants — p=.918
Phase 1 N=153 An Investigation of Early Life Stress and Depression
Major Depressive Disorder (MDD) · History of Childhood Sexual Abuse (CSA)
Primary: Dopamine Active Transporter Binding Potential — 3.191; 3.161; 3.175; 3.216 Ratio
Phase 1 N=81 Remote Mindfulness Training Following Early Life Adversity
Stress · Mindfulness · Early Life Adversity
Primary: Feasibility of Recruitment (Screened Eligible) — 81; 56; 112; 642 Participants
N/A N=32 Activating and Connecting Teens (ACT) Study
Depression
Primary: Depression — 9.63 score on a scale
N/A N=43 Neural Changes Associated With a Mindfulness-based Intervention for Young Adults With Childhood Maltreatment
Depression · Anxiety · PTSD
Primary: Changes in Subjects' Perceived Stress Level — -5.526; 1.000 score on a scale
N/A N=131 Neurobiological Responses in Alcoholism and Early Trauma
Alcohol Use Disorder · Early Trauma Complications
Primary: Brain Response — .015; .010; -.013; .08 unitless — p=<0.05
N/A N=15 Adolescent Attention to Emotion Study
Depression
Primary: Affect-biased Attention Following Neurofeedback (Immediately Post-Intervention) — .41 Proportion (0-1) — p=.004
N/A N=15 The S.M.A.R.T. Project: Stress Management and Resilience Training for Teens
Depression Mild · Resilience, Psychological · Adolescent Behavior
Primary: Time to Incident Depression — 36; 18.86 weeks — p=0.02
N/A N=39 Examining the Role of Pain in the Link Between Early Childhood Adversity and Psychopathology
Child Development
Primary: Pain Tolerance — 44.72; 45.09 seconds
N/A N=120 Adolescent Trauma Recovery and Stress Disorders Collaborative Care (ATRSCC) Model Program Trial
Post-traumatic Stress Disorder · Alcohol Abuse · Alcohol Dependence
Primary: Number of Patients With High Levels of Adolescent PTSD Symptoms — 9; 12; 11; 12 Participants — p=0.71
N/A N=39 Transcranial Magnetic Stimulation for Adolescent Depression
Major Depressive Disorder
Primary: Hamilton Depression Rating Scale — 9.38 score on a scale
N/A N=21 A Study of Adolescents Undergoing a Mindfulness Training During COVID-19
Healthy
Primary: Change in SDQ Emotional Problems — 2.08; -4.49 units on a scale — p=0.38
N/A N=176 Triple Vulnerability? Circadian Tendency, Sleep Deprivation and Adolescence
Eveningness/Sleep
Primary: Total Sleep Time (TST) Average on Weeknights Via Daily Sleep Diary — 24.72; 13.02 Minutes — p=0.34
N/A N=96 Effects of a Single-session Implicit Theories of Personality Intervention on Early Adolescent Psychopathology
Anxiety Symptoms · Depressive Symptoms
Primary: Change in Children's Depression Inventory (CDI) From Baseline to 9-month Follow-up — 12.35; 11.76; 11.54; 11.66 scores on a scale
N/A N=168 A Study Examining Adolescents With Non-Suicidal Self-Injury
Self-Injurious Behavior · Deliberate Self-Harm
Primary: Self-Injurious Thoughts and Behaviors Interview (SITBI) - Lifetime Episodes — 73.29; 0 episode count
N/A N=80 Examining Reward-Related Predictors and Mechanisms of Change in BA Treatment for Anhedonic Adolescents
Anhedonia
Primary: Change in Anhedonic (Snaith-Hamilton Pleasure Scale; SHAPS) Symptoms — 7.06; -1.29 units on SHAPS scale
N/A N=202 Affective Social Buffering
Social Stress · Adolescent Behavior
Primary: Cortisol AUCi — -93.6397; -68.0959; -106.9105 (ug/dL)*minutes
N/A N=50 Coping Long Term With Attempted Suicide - Adolescents
Suicide
Primary: Number of Participants Who Repoorted a Suicide Event — 8; 8 participants — p=.87
N/A N=186 Sibling-Support for Adolescent Girls (SSAGE)
Anxiety · Depression · Mental Illness
Primary: Diagnostic and Statistical Manual of Mental Disorders (DSM)-5 Level 1 Cross-Cutting Symptom — 44; 42; 24; 28 Participants
N/A N=2,452 Testing Scalable, Single-Session Interventions for Adolescent Depression in the Context of COVID-19
Depression
Primary: Change in Adolescent Depressive Symptom Severity — 14.31; 14.15; 14.22; 12.57 Score on a scale
N/A N=94 Stress and the Sympathetic Nervous System in Adults With Depression
Major Depressive Disorder
Primary: Percent of Days Participants Report Stressors — 36; 40 percent of days
N/A N=53 Stress in Inflammatory Bowel Disease
Inflammatory Bowel Diseases · Psychological
Primary: Retention Rate — 23; 25; 19; 22 Participants
N/A N=177 Shifting Perspectives: Enhancing Outcomes in Anorexia Nervosa With CRT
Anorexia Nervosa
Primary: Change in Cognitive Flexibility - Condition 4 Trail Making Test of DKEFS — 11.89; 10.94; 11.47; 11.14 score on a scale — p=.507
N/A N=120 Mindfulness-Based Intervention for Depression and Insulin Resistance in Adolescents
Type 2 Diabetes · Depression · Insulin Resistance
Primary: Intervention Fidelity — 90; 90; 97.5; 100 Expert ratings ranging from 0-100%
N/A N=93 Preschooler Emotion Regulation in the Context of Maternal Borderline Personality Disorder
Borderline Personality Disorder · Emotional Problem
Primary: Maternal Emotion Dysregulation — 82.35; 91.8 score on a scale — p=.002
Phase 2 N=90 An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression
Depressive Disorder
Primary: Children's Depression Rating Scale - Revised — 36.0; 37.5 score on a scale — p=0.76
N/A N=17 Pediatric Aggression and Violence
Pediatric Aggression and Violence
Primary: Salivary Hormone Correlation With Brief Rating of Aggression by Children and Adolescent (BRACHA) Score — 0.8; 0.4; 0.3; 0.4 ul/dL
N/A N=269 Does Social Buffering Continue to be Effective Over the Peripubertal Period When Friends Share the Stressor Experience?
Adolescent Behavior · Social Stress
Primary: Cortisol AUCi — 0.0043; 0.0256; 0.0177; 0.022 (ug/dl)*minutes
N/A N=42 HEALTHY (Health Education Adolescent Leadership Training to Help Youth) Leaders
Stress
Primary: Number of Participants Reporting Pediatric Symptoms as Assessed by the Pediatric Symptom Checklist-17 (PSC-17) — 3; 2; 4; 3 participants