N/A N=28 Enhancing Well-Being Through Exercise During Old Age
Depression · Osteoarthritis
Primary: Attendance of the Fit & Strong! Intervention Classes — 10 Classes attended
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=50 Maintaining Cognitive Health in Aging Veterans
Healthy People Programs
Primary: Knowledge of Memory Aging Questionnaire-Revised — 19.8; 19.5 units on a scale
N/A N=293 Decision Making and Implementation of Aging-in-Place/Long Term Care Plans Among Older Adults
Alzheimer Disease · Mild Cognitive Impairment · Long-Term Care Planning
Primary: Rate of Participant Long Term Care Planning for Alzheimer's Dementia/Memory Loss — 173 Participants — p=.6539
N/A N=63 Adaptability and Resilience in Aging Adults-2
Aging · Chronic Low-back Pain
Primary: Session-level Engagement — 6.3 score on a scale
N/A N=285 Evaluation of the Wits Workout Wellness Program for Older Adults
Cognitive Decline · Social Isolation · Health Behaviors
Primary: Change in Cognitive Function — 0.28; .65; 1.84; -.73 T score
N/A N=50 Aging With Long Term Physical Disabilities
Physical Disability
Primary: In-Home Occupational Performance Evaluation (I-HOPE) Activity Score — 0.73; 0.72; 0.76; 0.69 score on a scale — p=0.068
N/A N=505 A Community Wellness Program for Adults Living With Long-term Physical Disability
Physical Disability
Primary: Change in Self-reported Ability to Participate in Community Activities From Baseline to 6 Months — 2.49; 1.25; 0.09 score on a scale — p=<0.01
N/A N=242 Wellness Self-Management
Mental Illness · Chronic Medical Illness
Primary: Short Form-12 (SF-12) General Health (Norm Based) — 40.4; 38.9; 42.5; 41.6 units on a scale — p=0.362
N/A N=19 Maintaining Autonomy as we Age. Strategy Training for Age-related Executive Dysfunction.
Aging
Primary: Total Number of Goals Improved to Criterion on the Canadian Occupational Performance Measure (COPM) — 50; 19.6; 50; 32.6 percentage of untrained goals improved — p=0.03
N/A N=14 Enhancing Physical Function in the Long-term for Older Adults
Weight Loss Maintenance
Primary: Proportion Retention — 93 percent of participants
Phase 2 N=32 Healthy Aging Through Functional Food
Glucose Intolerance · Aortic Stiffness · Vasodilation
Primary: Area Under the Curve for Oral Glucose Tolerance Test (oGGT) — 10.8; 11.0; 9.9; 10.6 mM h
N/A N=176 Mindful Movement for Physical Activity and Wellbeing in Older Adults- A Hybrid Effectiveness-Implementation Study
Physical Inactivty · Wellbeing · Mindfulness
Primary: Moderate-Vigorous Physical Activity (MVPA) in 10 Min Bouts — 18.35; 15.54 minutes per week
N/A N=48 Ageing and Acute Care Physicians' Performance
Ageing
Primary: CRM Performance During First Sim Scenario Assessed by Ottawa Global Rating Scale (GRS) — -0.299 Pearson correlation coefficient — p=0.039
Phase 2 N=45 Targeting Inflammation to Treat Cardiovascular Aging
Vascular Stiffness · Endothelial Dysfunction · Diastolic Dysfunction
Primary: Carotid-femoral Pulse Wave Velocity (CFPWV) — 831.3; 785.1; 538.0; 839.6 cm/sec
N/A N=210 Physical Health in Midlife: Influences of Adversity and Relationships Over Time
Cardiovascular Disease · Type 2 Diabetes
Primary: Hormonal Levels — 910000; 5.8; 22.8; 171.8 ng/ml
N/A N=50 Activate For Life: mHealth Intervention To Address Pain And Fatigue In Low-income Older Adults Aging In Place
Pain, Chronic · Fatigue Syndrome, Chronic · Aging
Primary: Older Adult Pain Intensity — -3.25; -2.8; -0.5 T-score
N/A N=60 Mindfulness Training in Healthy Older Veterans
Aging
Primary: Geriatric Depression Scale Change Score — .89; 0.50 score on a scale
N/A N=42 FrAilty Care and wEll-funcTion in Community Dwelling Older Adults
Frailty · Sarcopenia · Aging
Primary: Pilot Evaluation - Percentage of Participants Retained at Follow up — 10; 10; 9; 11 Participants
N/A N=75 Improving Aging in Place in Subsidized Housing
Physical Disability · Cognitive Impairment · Physical Activity
Primary: Change in Precipitating Events Project (PEP) Functional Status Scale From Baseline to 2 Months for Immediate Intervention Sites and Waitlist Control Sites — -1.3; 0.6…
N/A N=223 Aging & HIV/AIDS Neurocognitive Sequelae and Functional Consequences
HIV Infections
Primary: Neuropsychological Status (i.e., Cognitive Functioning) — 0.008; .484; -.084; -.482 z-score composites of cognitive domains — p=0.001
N/A N=69 Exercise for Healthy Aging: The Impact of HIV and Aging on Physical Function and the Somatopause
HIV · Inflammation · Obesity
Primary: Time to Rise From a Chair 10 Times (Modified From the Original Short Physical Performance Battery) — -20; -20; -8; -10 percentage change
Phase 2 N=8 Acarbose Anti-aging Effects in Geriatric Subjects (Substudy B & C)
Aging
Primary: Change in Microbiome — 0; 0; 0 Operational Taxonomic Unit (OTU)
Phase 2 N=63 The HEALS Project - Health Education and Active Living for Surviving Seniors
Cancer Survivorship · Safety and Efficacy · Quality of Life
Primary: Retention Rates and Class Attendance — 91; 81; 79; 83 percentage of participants
N/A N=385 Advance Planning for Home Services for Seniors
Alzheimers, Falls, Aging in Place
Primary: Planning Behavior Score at 1-month — 16.97; 16.80; 17.19; 15.88 units on a scale — p=0.0054
N/A N=90 Health, Aging and Later-Life Outcomes
Aging
Primary: Number of Participants That Sustained >10% Caloric Restriction — 7; 12 Participants
N/A N=71 Long-term Caloric Restriction and Cellular Aging Markers
Aging
Primary: Telomere Length — 0.96; 1.06; 1.06; 1.22 ratio
N/A N=91 Ambient Independence Measures for Guiding Care Transitions
Aging
Primary: Number of Participants With Increased Need for Assistance During 3-year Study Period — 13; 16 Participants
N/A N=283 Healthy Aging Resources to Thrive (HART)
Sedentary Lifestyle
Primary: Change in Time Spent Sitting or Lying Down at 6 Months — -40.36; -8.51 Minutes — p=0.003
Phase 3 N=1,635 The LIFE Study - Lifestyle Interventions and Independence for Elders
Sedentary Lifestyle · Risk of Disability · Aging
Primary: Major Mobility Disability, Defined as Incapacity to Walk 400 Meters — 246; 290 participants — p=0.03
N/A N=13 Efficacy of a Multimodal Brain Health Intervention for Older African Americans
Cognitive Impairment, Mild · Cognitive Decline
Primary: Daily Average Steps Recorded by Actigraphy Watch — 2570; 1140 daily step count