N/A N=89 The Effect of Anesthesia on Neurodevelopmental Outcome (NDO)
Anesthesia; Adverse Effect · Congenital Heart Disease · Neurodevelopmental Disorders
Primary: Bayley III — 91; 93; 88; 90 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=30 Assessment of Cognitive Function After Surgery in Two Types of Anesthesia in Patients Operated for Breast Cancer
Patients With Breast Cancer and Breast Surgery Requiring
Primary: Presence of Cognitive Impairment — 29.5; 29 score on a scale
Phase 4 N=798 Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery
Heart Disease
Primary: Number of Patients With Atrial Arrhythmia — 121; 134 Participants — p=0.34
N/A N=51 Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Hypotension · Anesthesia
Primary: Number of Participants Who Had Hypotensive Events — 8; 21 Participants — p=0.01
Phase 2 N=49 Anesthetics to Prevent Lung Injury in Cardiac Surgery
Inflammatory Lung Injury · Ischemia-Reperfusion Lung Injury · Postoperative Pulmonary Complications
Primary: Bronchoalveolar Lavage (BAL) Concentration of TNF Alpha (pg/mL) — 0.53; 0.53; 22.06; 102.04 pg/mL
N/A N=30 Anesthesia During Neurophysiologic Monitoring in Scoliosis Patients
Idiopathic Scoliosis
Primary: Amplitude Required to Elicit the MEP — 307; 417 milliamperes
Phase 4 N=32 Angiotensin II in General Anesthesia
Hypertension
Primary: Median Dose Required to Increase the Systolic Blood Pressure (SBP) — 35; 43; 45 ng/kg/min
Phase 4 N=18 The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects
Airway Complication of Anaesthesia · Healthy
Primary: Upper Airway Closing Pressure — -9.83; -10.77 cm H20
Phase 4 N=81 Impact of Anesthetic Choice (Sevoflurane Versus Desflurane) on Airway Reflex Recovery in the Context of Antagonized Neuromuscular Block
Airway Reflexes, Protective · Recovery After Neuromuscular Block · Anesthetic Recovery
Primary: Recovery of Ability to Swallow After Neostigmine/Glycopyrrolate Antagonism of Rocuronium Paralysis. — 16; 25; 10; 6 participants — p=0.11
Phase 4 N=23 Anesthesia and Postoperative Pain
Postoperative Pain
Primary: Score on a Pain Rating Scale (Numerical Analog Score) — 1.5; 4.9 scores on a scale
Phase 3 N=59 The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort
Pain, Procedural
Primary: Post Operative Pain — 13; 10 Participants
Phase 3 N=2,108 Regional Anesthesia and Breast Cancer Recurrence
Breast Neoplasms
Primary: Number of Participants Who Had Breast Cancer Recurrence After Breast Cancer Surgery — 111; 102 participants — p=0.84
Phase 1 N=54 General Anesthesia Emergence Induced by Methylphenidate
Delayed Emergence From Anesthesia
Primary: Emergence Time — 9; 9 minutes
N/A N=257 Anesthesia Counseling, Consent, & Professionalism
Communication · Preoperative · Ethics
Primary: Number of Participants Who Recall Anesthesia Team Members — 30; 49 Participants
N/A N=67 Markers of Liver Apoptosis After Anesthesia With Sevoflurane or Propofol
Liver Dysfunction
Primary: Changes in the M30 and M65 Markers Related to the Anesthesia Type — 237.27; 279.97; 427.33; 470.30 U/L
N/A N=68 Anesthetic Depth and the Incidence of Emergence Agitation in Children Undergoing Strabismus Surgery
Strabismus
Primary: the Pediatric Anesthesia Emergence Delirium (PAED) Score — 12.5; 11.4; 6.5; 5.4 score on a scale
N/A N=199 Cognitive Effects of Inhalational Versus Intravenous General Anesthesia in the Elderly
Lumbar Spondylosis · Cervical Spondylosis · Hip Osteoarthritis
Primary: Change in Neurocognitive Performance (Z-score) — .09; -.20; -.42; .01 z score
N/A N=60 Effect General and Regional Anesthesia on Glycocalyx
Anesthesia · Glycocalyx · Perfused Boundary Region
Primary: Change in Perfused Boundary Region (PBR) — 2.20; 2.09 micrometer
N/A N=105 Anesthesia and Lymphocytes Apoptosis
Anesthesia
Primary: Lymphocyte Count — 0.55; 0.73; 0.73 cells/nanoliter
N/A N=72 Positive Pressure at Induction of Anesthesia in Children
Continuous Positive Airway Pressure · Hypoxia · General Anesthesia
Primary: Time Between Onset of Apnea and the Drop in 95% Oxyhemoglobin Saturation Levels — 227.65; 133.68 seconds — p=<0.0001
N/A N=67 The Effect of Intravenous Anesthetics on Fear Learning and Memory
Phobias
Primary: GSR Trial 1 — .62; .55; .55; .67 units on a scale
N/A N=121 Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia
Emergence Delirium
Primary: Emergence Agitation — 3.9; 2.5 Score on a scale — p=0.001
Phase 4 N=10 Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain
Acute Pain · Chronic Pain · Hernia
Primary: Pain Score, Chronic — 1.7; 1.5; 0; .8 score on a scale
N/A N=100 General Anesthesia With ETT vs LMA in Patients Undergoing Ablation for Atrial Fibrillation
Atrial Fibrillation
Primary: Procedure Time (Minutes) — 128.7; 137.8 minutes
N/A N=300 The Effect of Age on the Incidence of Postoperative Residual Neuromuscular Blockade
Residual Neuromuscular Blockade in Elderly Patients
Primary: Incidence of Residual Neuromuscular Blockade — 45; 86 participants
Phase 1 N=32 Memory Modulation by Pain During Anesthesia
Amnesia · Pain · Anesthesia
Primary: Memory Testing — 1.20; .56; .82; 1.18 d' score
N/A N=54 Ketamine Infusion and Hypoventilation
Hypoventilation
Primary: Intraoperative Hypoventilation — 1.2; 65 % time
Phase 4 N=172 Muscle Relaxation for Pediatric Adenotonsillectomy
Tonsillectomy
Primary: Cumulative Intra- and Postoperative Opioid Consumption — 0.209; 0.188 IV morphine milligram equivalent/kg — p=0.123
N/A N=40 The Effect of Depth of Anesthesia as Measured by Bispectral Index (BIS) on Emergence Agitation in Children
Emergence Agitation
Primary: Peak Pediatric Assessment of Emergence Delirium (PAED) Score Within the First 30 Minutes of Reaching the Recovery Room (Post-Anesthesia Care Unit) — 8.6; 6.7 units on a…
Phase 4 N=20 Physiological Effects of Nitrous Oxide on Anaesthesia
Anesthesia
Primary: Pa t/Pa0 Sevo (Arterial Partial Pressure of Sevoflurane), t=Time(Minutes) — 0.32; 0.44; 0.23; 0.32 ratio