Clinical Trial Search

Primary: Percentage of Appropriate Antimicrobial Prescriptions Recommended — 90 percentage of prescriptions appropriate

Primary: Simpson's Index of Diversity (Alpha Diversity) in Intestinal Microbiome — 10.2; 8.8; 9.7; 9.6 Index score

Primary: Percentage of Patient-visits Prescribed an Antimicrobial at Their ED Visit — 21.2; 20.9; 19.1; 21.6 percentage of visits prescribed an abx — p=0.35

Primary: Number of Events of Composite Morbidities and Mortality, Including Necrotizing Enterocolitis (NEC), Late Onset Sepsis (LOS), Bronchopulmonary Dysplasia (BPD) and Death…

Primary: Body Mass Index Z-score Difference at 48-72 Months, Exposed vs. No Antibiotics Less Than 24 Months — 0.04; 0.06; 0.04; 0.07 BMI z-score units

Primary: Inappropriate Antibiotic Prescribing for Patients With Acute Respiratory Infections (ARI) — 33.7; 52.7 inappropriate prescribing events

Primary: Antimicrobial Resistance (AMR) of Conjunctiva at 1 Week — 0; 0; 0 reads per million reads — p=1

Primary: Percentage of Cases Who Received Excessive Post-procedural Antimicrobials — 216; 644 Participants — p=0.004

Primary: Degree of Microbial Disruption: Number of Patients With Recovery of Bacterial Species Richness at 185 Days Post-antibiotics — 3; 3; 2; 3 Participants

Primary: Change From Baseline Antibiotic Consumption at 18 Months, in Primary Care — 1.71; 2.01 PID-number of packages per 1000 inhabit

Primary: Inappropriate Antibiotic Prescribing Rate for Qualifying Acute Respiratory Infection Diagnoses — 0.20; 0.19; 0.08; 0.09 proportion of visits

Primary: Richness of the Preterm Infant Microbiome — 12.8; 11 16S rRNA gene amplicon sequence variants

Primary: Subjects Who Developed Antibiotic Resistance Organisms — 0; 0; 1; 0 Participants

Primary: Number of Participants That Filled a Prescription in 20 Days — 16; 16 Participants — p=0.924

Primary: Days of Antibiotic Therapy in the First 14 Days Following Randomization — 7.6; 6.6 days

Primary: Guideline-concordant Antibiotic Use for Adults With Pharyngitis — 1458; 2477 Participants

Primary: The Number of Patients Receiving Appropriate Treatment — 44; 29 Participants

Primary: Number of Participants With Clinical Cure as of the Test-of-Cure (TOC) Visit in the Per Protocol Population — 457; 487; 182; 187 participants

Primary: Number of Cases of ABU That Are Treated Inappropriately With Antibiotics — 1.6; 0.6; 0.5; 0.6 cases/1,000 bed-days

Primary: Proportion of Asymptomatic Bacteriuria Treated With Antibiotics and Urinary Tract Infection Treated With Antibiotics — 31; 25 Participants

Primary: Number of Participants With Surgical Site Infections — 11 participants

Primary: Change in the Abundance of Staphylococcus Aureus in the Nose After Decolonization — -4174 fg/uL

Primary: Changes to the Urinary Microbiota — 3; 2; 1 participants

Primary: Death — 5; 5; 7; 1 Participants

Primary: Bacteria Prevalence in Stool — 22.3; 20.9; 18.0; 25.5 percentage of bacterial genera in stool — p=<0.05

Primary: Number of Participants With Urinary Tract Infection — 30; 22; 0; 0 Participants

Primary: Days of Antibiotic Therapy Per 1000 Days of Care — 710; 744 Days of Antibiotic Therapy/1000 Bed Days

Primary: Proportion of Patients Experiencing a Serious Bacterial Infection — 12.5; 6.8; 15.9 percentage of participants — p=0.218

Primary: Number of Patients Who Were Cured — 91; 117 Participants — p=<0.05

Primary: Number of Participants With the Presence of Post-Operative Infection — 2; 2 Participants