Phase 4 N=26 Inhaler Lung Deposition in Chronic Obstructive Pulmonary Disease (COPD)
CHRONIC OBSTRUCTIVE PULMONARY DISEASE · ASTHMA · HEALTHY SUBJECTS
Primary: ANALYSIS OF LUNG DEPOSITION - Penetration Index — 0.8; 0.72; 0.69; 0.58 ratio
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=56 COPD Assessment and Management Bundle Versus Usual Care
Chronic Obstructive Pulmonary Disease
Primary: Number of Participants With Accurate Classification of Irreversible Airflow Obstruction — 10; 5 Participants
Phase 3 N=122 GW815SF For Chronic Obstructive Pulmonary Disease (Chronic Bronchitis, Emphysema)
Pulmonary Disease, Chronic Obstructive
Primary: Number of Participants With Any Adverse Events (AEs) and Serious AEs (SAEs) — 120; 27 Participants
N/A N=1,507 Chronic Obstructive Pulmonary Disease (COPD) Maintenance Treatment Patterns in China
Pulmonary Disease, Chronic Obstructive
Primary: Number of Participants Who Received COPD Prescription for Maintenance Treatment at Baseline — 735; 68; 554; 105 Participants
N/A N=252 Chronic Obstructive Pulmonary Disease (COPD) Biomarker Identification Study
COPD
Primary: Spirometry Measurement: Percentage of Predicted Forced Expiratory Volume in 1 Second (FEV1 %Pred) — 75.572; 100.837; 108.311; 111.849 percent of predicted FEV1 — p=<0.0001
N/A N=240 Improving Patient-Centered Care Delivery Among Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease
Primary: Mean Number of Chronic Obstructive Pulmonary Disease (COPD)-Related Hospitalizations and Emergency Department (ED) Visits Per Patient Within Each Study Arm — 0.72; 1.40…
N/A N=1,371,146 Characteristics and Treatment Patterns of Patients With Chronic Obstructive Pulmonary Disease (COPD), Initiating Tio+Olo or Other Maintenance Therapies in the US and the UK: A Retrospective Claims Database Study
Pulmonary Disease, Chronic Obstructive
Primary: Age of the Chronic Obstructive Pulmonary Disease (COPD) Patients at the Time of COPD Diagnosis - US — 65.6; 64.4 Years
N/A N=124 Electronic Proactive Outreach for Smokers With COPD
Pulmonary Disease, Chronic Obstructive · Smoking
Primary: Participation in Tobacco Cessation Treatment — 9; 29 Participants
Phase 4 N=584 Efficacy and Tolerability Study in Severe Chronic Obstructive Pulmonary Disease (COPD) Patients
Chronic Obstructive Pulmonary Disease (COPD)
Primary: Pre-dose FEV1 — 1.079; 1.009 Ratio — p=<.0001
N/A N=81 Effect of Increased Fruit and Vegetable Intake on Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease
Primary: Self-reported Intake of Fruit and Vegetables (Number of Portions Per Day); — 1.9; 6.1 Portions per day
N/A N=34 RESP-FIT: Technology-Enhanced Self-Management in COPD
COPD
Primary: Intervention Feasibility (Number of Participants Who Adhered to Treatment) — 13; 14 Participants
N/A N=80 Peak Inspiratory Flow Rates in Patients With COPD
COPD
Primary: Occurrence of Suboptimal PIFR — 22.7 percentage of participants
N/A N=169 Screening for Chronic Obstructive Pulmonary Disease in Patients With Acute Coronary Syndromes
Chronic Obstructive Pulmonary Disease · Acute Coronary Syndromes
Primary: COPD Diagnosis — 39 participants
N/A N=200 Chronic Obstructive Pulmonary Disease Patient Preferences Survey
Pulmonary Disease, Chronic Obstructive
Primary: Number of Participants Who Prioritized Healthcare Topics — 90; 79; 23; 22 participants — p=.91
Phase 4 N=30 Dynamic Hyperinflation and Tiotropium
COPD
Primary: Bronchodilator Response:Peak FEV1(L)(Forced Expiratory Volume in One Second)- — 1.74; 1.82 liters — p=0.027
N/A N=25 Vitabreath Pilot in Chronic Obstructive Pulmonary Disease (COPD) Patients
COPD · Dyspnea
Primary: Average Distance During Modified 6 Minute Walk Test — 128.0; 129.9; 137.5; 121.3 meters — p=0.02
N/A N=1,084 Evaluation of Lung Function and Symptoms in Patients Diagnosed With Chronic Obstructive Pulmonary Disease (COPD) on Long-Acting Bronchodilator Monotherapy
Pulmonary Disease, Chronic Obstructive
Primary: Percentage of Participants Whose Post-albuterol Forced Expiratory Volume in One Second (FEV1) Was <80% Predicted Normal — 70; 30 percentage of participants
N/A N=376 Improving the Quality of End-of-Life Communication for Patients With Chronic Obstructive Pulmonary Disease (COPD)
Pulmonary Disease · COPD · Chronic Bronchitis
Primary: Effect of Intervention on Quality of Patient Clinician Communication About End-of-Life Care(QOC) Scale — 23.3; 19.2; 34.0; 25.5 units on a scale — p=0.03
N/A N=4,832 An Evaluation of Post Discharge Utilization Among Patients With an Acute Exacerbation of COPD
Chronic Obstructive Pulmonary Disease
Primary: Healthcare Utilization — 1080; 920 Participants — p=0.041
N/A N=463 Longitudinal Follow up to Assess Biomarkers Predictive of Emphysema Progression in Patients With COPD (Chronic Obstructive Pulmonary Disease)
Pulmonary Disease, Chronic Obstructive · Pulmonary Emphysema
Primary: Absolute Change From Baseline at Week 156 in Adjusted Lung Density (ALD) Based on Percentile Density at 15% (PD15) Adjusted for Lung Volume — -0.27; -3.15; -5.04; -4.74…
N/A N=22 Non-invasive Ventilation System in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
Pulmonary Disease, Chronic Obstructive · Airflow Obstruction, Chronic · Chronic Obstructive Airway Disease
Primary: Device Tidal Volume — 180 mL
N/A N=59 Comprehensive Self-management Support for COPD Patients
COPD · Self-management Behaviors
Primary: COPD Assessment Test (CAT) — 22.0; 21.9; 21.5; 22.7 score on a scale
N/A N=153 The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPD
COPD · Emphysema · Chronic Bronchitis
Primary: 6-Minute Walk Test Distance — 25; 37 meters — p=0.189
Phase 4 N=278 Ease of Use and Correct Use Study of Placebo ELLIPTA® Inhaler in COPD Subjects
Pulmonary Disease, Chronic Obstructive
Primary: Percentage of Participants With COPD Who Rate the Use of the ELLIPTA Inhaler as Easy or Very Easy, Among Those Who Demonstrate Correct Use of the Inhaler at the End of…
N/A N=141 Treatment of Depressed Chronic Obstructive Pulmonary Disease Patients
Pulmonary Disease, Chronic Obstructive · Major Depression
Primary: Composite Antidepressant Score Scale (CAD) — 29; 25; 9; 20 Participants
N/A N=50 Nurse Coach-Led Early Palliative Care for Older Adults With COPD and Their Care Partners: The Project EPIC Pilot RCT
COPD
Primary: Intervention Feasibility — 9.2; 6.4 Sessions
N/A N=154 Preference Tiotropium Respimat Study in COPD
Pulmonary Disease, Chronic Obstructive
Primary: Total Mean Score of the Validated Patient Satisfaction and Preference Questionnaire (PASAPQ) — 80.71; 79.92 units on a scale
N/A N=17,464 A Study Based on Health Insurance Data About the Treatment of Patients Who Have Been Newly Diagnosed With Chronic Obstructive Pulmonary Disease (COPD)
Pulmonary Disease, Chronic Obstructive
Primary: Description of Real-life Drug Treatment After Incident Diagnosis - COPD-12 Sample — 35.6; 30.3; 29.1; 25.0 Percentage of Patients
Phase 3 N=130 Study Evaluating Preference, Satisfaction and Ease of Use of Inhalers in Chronic Obstructive Pulmonary Disease (COPD) Diagnosed Patients
Chronic Obstructive Pulmonary Disease (COPD)
Primary: Percentage of Patients Who Prefer Genuair Device Versus Handihaler Device at Visit 2 — 68.6; 18.1; 13.3 Percentage of Patients
N/A N=2,031 Safety and Effectiveness of Spiriva in COPD (Chronic Obstructive Pulmonary Disease) Patients Under the Real Condition of Usual Practice
Pulmonary Disease, Chronic Obstructive
Primary: Change of Physician's Global COPD (Chronic Obstructive Pulmonary Disease) Assessment After 8-week of Treatment Severe COPD Patients Without Concomitant LABA (Long-acting…