N/A N=26 Effect of Cross Frequency tACS on Cognitive Control
Cognitive Control · Executive Function
Primary: Reaction Time for Trials With High Abstraction Relative to Low Abstraction — 0.1247; 0.1444; 0.1022 seconds — p=0.031
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 4 N=121 Emotional and Cognitive Control in Late-Onset Depression
Depression
Primary: Change in Depression Severity (Measured by Montgomery Asberg Depression Rating Scale) — 25.26; 1.03; 13.78; 1.08 score on a scale — p=< 0.025
N/A N=39 Theta Connectivity in Working Memory
Executive Function
Primary: Number of Remembered Items — 1.72; 1.68; 1.68; 1.65 remembered items — p=0.783
N/A N=108 Behavioral Differences in Effortful Control
Healthy
Primary: Reaction Time on the Multi-Source Interference Task — 300; 330; 310; 280 milliseconds — p=0.159
N/A N=30 Enhancing Cognitive Control in Mild Cognitive Impairment Via Non-invasive Brain Stimulation
Mild Cognitive Impairment
Primary: Divided Attention Performance — 9.29; 9.31 difficulty level acheived
N/A N=72 Enhancing Transdiagnostic Mechanisms of Cognitive Dyscontrol
Anxiety Disorders · Depression · Posttraumatic Stress Disorder
Primary: Change in Cognitive Performance — 4.92; 8.18; .27 score on a scale
N/A N=62 Improving Attentional and Cognitive Control in the Psychological Treatment of Intrusive Thoughts
Obsessive-Compulsive Disorder · Generalized Anxiety Disorder · Major Depressive Disorder
Primary: Transdiagnostic Repetitive Negative Thinking (Measured by the Perseverative Thinking Questionnaire [PTQ]) Assessed in Phase I (Pilot Trial) and Group Differences…
N/A N=39 cTBS/fMRI Study of Hierarchical Control in the PFC
Transcranial Magnetic Stimulation
Primary: PFC-PPC Effective Connectivity — 0.3646; 0.3756; 0.3425; 0.4519 Hertz — p=0.5736
N/A N=39 iTBS/fMRI Study of Hierarchical Control in the PFC
Transcranial Magnetic Stimulation
Primary: PFC-PPC Effective Connectivity — 0.2177; 0.2248; 0.1911; 0.3157 Hertz — p=0.599
N/A N=58 Modulation of Cognitive Control Signals in Prefrontal Cortex by Rhythmic Transcranial Magnetic Stimulation
Executive Function
Primary: Number of Remembered Items — 1.863; 1.754; 1.796; 1.797 number of remembered items — p=0.263
N/A N=66 Arbitration Between Habitual and Goal-directed Behavior in Obsessive-compulsive Disorder: Circuit Dynamics and Effects of Noninvasive Neurostimulation
OCD · Decision-Making · tDCS
Primary: Strength of Behaving Model-based (Goal-directed) — 0.09; 0.07; -0.08; 0.06 units on a scale
N/A N=30 Top-Down Executive Control in Traumatic Brain Injury (TBI), PTSD and Combined
PTSD · TBI (Traumatic Brain Injury)
Primary: Functional Magnetic Resonance Imaging (fMRI) Correlation — .21; .19; .36 r-value
N/A N=38 Using Teleneuropsychology to Optimize Cognition in Healthy Aging: the Web-based Breakfast Game
Healthy Aging
Primary: Changes in the Breakfast Game Performance: Number of Tables Set Score — 1.61; 1.43 score on a scale (change)
N/A N=34 Inhibitory Control Adult Weight Management
Overweight and Obesity
Primary: BMI at Three Months — 34.53; 34.43 kg/m^2
N/A N=46 Targeting Self-regulatory Deficits Through Cognitive Remediation Intervention
Drug Use Disorders
Primary: Change in Stop Signal Reaction Time — -8.62 ms — p=.003
N/A N=184 Oscillatory Contributions to Working Memory and Attention
Young Adults
Primary: Behavioral Accuracy: Sub-study 1 — 86.3; 87.1 percentage of correct responses
Phase 4 N=23 Control of Cognition (Naltrexone, Methylphenidate, and ADHD Study (NMAS))
Healthy · Attention Deficit Hyperactivity Disorder
Primary: Reaction Time Variability on the Multi-Source Interference Task — .22; .23; .26; .20 seconds — p=.02
N/A N=35 Neural Bases of Cognitive Rehabilitation for Brain Injury
Brain Injury
Primary: Change From Baseline on a Composite Measure (Z-score) of Attention, Working Memory, and Executive Functions — 0.26; .01 Change to Z (composite) score
N/A N=75 Self-Control and Adult Cigarette Smokers
Smoking
Primary: Self- Control as Measured by the Change in the Length of Time Participants Can Hold a Hand-grip at Baseline and Follow-up (One Week After Baseline) — -9.36; 2.76; -4.32…
Early Phase 1 N=35 Remediation of Impaired Self-Regulation in Patients With Mild TBI
Mild Traumatic Brain Injury
Primary: Blood Oxygen Level Dependent (BOLD) Brain Signal Measured Using Functional MRI. — 270; 111 voxels — p=<0.0001
N/A N=35 Investigating the Causal Role of Prefrontal Control in Decision-making in Patients With Anhedonia
Major Depressive Disorder · Anhedonia
Primary: Change in the Percentage of Trials That the Participant Chooses to Perform the Hard Task — -0.30; -0.22; -0.09 percentage of trials — p=0.049
N/A N=42 A 14 Week Study of Mindfulness Effects on Attentional Control in Older Adults
Cognitive Aging
Primary: Performance in Attention Network Task Conflict Monitoring Over 14 Weekly Measurements — 51.6; 60.4; 51.2; 57.3 units on a scale — p=.024
Phase 4 N=37 Large-scale Brain Organization During Cognitive Control in ADHD
Attention Deficit Hyperactivity Disorder
Primary: Resting State Brain Network Organization — 0.223; 0.228 units on a scale — p=0.532
N/A N=72 Cognitive Training Trial
Attention Deficit Hyperactivity Disorder
Primary: Total ADHD Symptom Score From Vanderbilt ADHD Parent Rating Scale — 27.00; 26.63 units on a scale — p=.36
N/A N=38 Cognitive Ability Training in Seniors
Mild Cognitive Impairment
Primary: Neuropsychological Performance in Neuropsychological Test: Verbal Learning Memory Test (VLMT) — 57.2; 57.2 score on a scale — p=0.74
N/A N=20 Cognitive Training Video Game to Target Subclinical Depressive Symptoms in Youth
Depression · Subclinical Depressive Symptoms
Primary: Change in Depressive Symptoms as Measured by Children's Depression Inventory (CDI) — 8.85; 5.84 score on a scale
N/A N=27 Task Switching Behavior Between Target Templates During Visual Search in Healthy Adults
Healthy
Primary: Button Press Reaction Time — 1.68; 1.69; 1.76; 1.77 Seconds — p=<.05
N/A N=140 Noradrenergic Activity and Attention
Aging
Primary: Initial Eye-movements Toward Target and Distractor Shapes Measured by an Eye-tracker — 3.8; 4.4; 3.6; 4.5 percentage of first saccades
N/A N=40 Testing a Neurocognitive Model of Distancing Using Transcranial Magnetic Stimulation.
Emotion Regulation · Real Versus Sham Transcranial Magnetic Stimulation (TMS)
Primary: Change in Self-reported Valence (Distancing) From Baseline to 30 Minutes Post Stimulation. — .662; .668 score on a scale — p=.019
Phase 2 N=73 Cognitive Stimulation
Substance Use Disorders
Primary: Working Memory — 0.86; 0.04 digits recalled