Phase 3 N=84 Effect of Dexamethasone on Labor Induction
Dexamethasone · Pregnancy
Primary: First Bishop Score — 1; 1 score on a scale — p=0.618
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=41 Dexamethasone Dyspnea Study
Advanced Cancers · Hematologic Disorder · Solid Tumors
Primary: Number of Participants Who Completed the Dyspnea Numeric Rating Scale — 18; 17 Participants
Phase 2 N=5 Dexamethasone Treatment of Congenital Adrenal Hyperplasia
Adrenal Hyperplasia, Congenital
Primary: Percent Difference in the Mean Log Transformed Area Under the Curve of 17-hydroxyprogesterone Between Regimens — 3.16; 3.91 Log Mean Area Under the Curve — p=0.09
Phase 4 N=209 Dexamethasone for Migraine - Dose Comparison
Migraine
Primary: Number of Subjects With Headaches Who Have Sustained Headache Relief for 48 Hours — 35; 42 Participants
Phase 3 N=308 Use of Dexamethasone in Pediatric Asthma Exacerbations
Asthma
Primary: Number of Participants Returning to Care Following Discharge From the Emergency Department — 14; 12 Participants
Phase 2 N=27 Effect of Dexamethasone on Reduction of Macular Thickness in Diabetic Patients, a Randomized Clinical Trial
Diabetic Macular Edema
Primary: Macular Thickness at 3 Days After Intravitreous Dexamethasone — 438.44; 465.22; 368.22 µm
Phase 4 N=92 Ideal Steroids for Asthma Treatment in the PICU
Asthma Childhood
Primary: Length of Stay — 2.9; 2.9 days — p=0.632
Phase 4 N=49 Dexamethasone for Post-cesarean Delivery Pain
Pain, Postoperative · Postoperative Nausea and Vomiting
Primary: Morphine Consumption at 24 Hours Post-op — 15; 13.75 milligram — p=0.740
Phase 3 N=142 Randomized Open Investigation Determining Steroid Dose
Covid19
Primary: All Cause Mortality at 28 Days — 15; 12 Participants
N/A N=29 Cochlear Implant With Dexamethasone Eluting Electrode Array
Sensorineural Hearing Loss · Bilateral Hearing Loss
Primary: Comparison of Monopolar (MP1+2) Impedance Measurement (kOhms) Between Randomization Groups at 6 Months Postoperative — 3.99; 8.66 kOhms
Phase 4 N=200 Effect of Low-Dose Dexamethasone on the Incidence of Hyperglycemia Following Surgery
Postoperative Complications
Primary: Serum Blood Glucose Concentrations — 101; 137; 140; 141 mg/dl
Phase 3 N=200 XERECEPT® (hCRF) for Patients Requiring Dexamethasone to Treat Edema Associated With Brain Tumors
Brain Edema · Brain Tumor
Primary: The Proportion of Patients in Each Treatment Group Who Are Responders at Week 2 and Continue to be Responders at Week 5 — 57; 46 participants
Phase 2 N=51 Dexamethasone Administration To Improve Patient Recovery In Ambulatory Vaginal Prolapse Surgery: Is There A Role?
Quality of Recovery · Same Day Surgery · Nausea and Vomiting, Postoperative
Primary: Questionnaire: Quality of Recovery 40 — 174; 167 score on a scale
N/A N=89 Dose Response Study of Dexamethasone in Combination With Bupivacaine 0.25%
Post Surgical Pain
Primary: Primary Outcome Variable is Post Operative Sensory Block Duration — 12.1; 22.3; 23.3; 21.2 hours
Phase 3 N=97 Trial of One Versus Two Doses of Dexamethasone for Pediatric Asthma Exacerbation
Asthma
Primary: Treatment Failure — 6; 3 Participants — p=0.3
Phase 3 N=77 Decadron as Adjuvant in Femoral Nerve Blocks in Knee Arthroscopy
Knee Injury
Primary: Intra-operative and Post-operative Opioid Consumption — 2; 2; 3 doses
Phase 4 N=162 Dexamethasone for Post Traumatic Headache
Post-Traumatic Headache
Primary: Frequency of Moderate or Severe Headache After Emergency Department (ED) Discharge — 31; 29; 42; 44 Participants — p=0.751
Phase 4 N=52 Dexamethasone for Post Cesarean Delivery Analgesia
Postoperative Pain
Primary: Postoperative Analgesia — 11.8; 15 milligrams of morphine — p=0.32
Phase 4 N=110 Comparing the Effects of Different Doses of Dexamethasone to Treat Inpatient COVID-19
Covid19
Primary: Number of Participants With Clinical Improvement of Greater Than or Equal to 2 Points Using the WHO-OSCI at Day 28 — 37; 43 Participants
Phase 3 N=3,154 Dexamethasone Compared With Prednisone During Induction Therapy and Methotrexate With or Without Leucovorin During Maintenance Therapy in Treating Patients With Newly Diagnosed High-Risk Acute Lymphoblastic Leukemia
Acute Lymphoblastic Leukemia · Adult B Acute Lymphoblastic Leukemia · Childhood B Acute Lymphoblastic Leukemia
Primary: Comparison of the Increase in Cure Rate of High Risk ALL Without Causing More Serious Side Effects Between Interventions — 83.2; 81.6; 69.1; 91.2 percentage of…
Phase 4 N=122 Dexamethasone for the Prevention of Post-operative Nausea and Vomiting in Patients Undergoing Cesarean Sections
Postoperative Nausea and Vomiting
Primary: Incidence of Post-operative Nausea and/or Vomiting — 29; 24 Participants
Phase 2 N=24 Dexamethasone Solution for the Treatment of Oral Lichen Planus
Lichen Planus
Primary: Change in Oral Sensitivity — -4.5; -6.0 score on a scale
Phase 2 N=29 Dexamethasone Solution and Dexamethasone in Mucolox™
Oral Lichen Planus · Mucous Membrane Pemphigoid · Pemphigus Vulgaris
Primary: Mean Change From Baseline in Oral Pain Scores on the Visual Analog Scale (VAS) at 4 Weeks — 6.3; 4.4 score on a scale
Phase 4 N=27 Dexamethasone Plus Virtual Reality Exposure Therapy for PTSD
PTSD
Primary: Change in The Clinician Administered PTSD Scale (CAPS)Scores — -11; -15.22 units on a scale
Phase 4 N=120 Post Operative Sore Throat and Dexamethasone
Sore Throat · Pain
Primary: Subjects Assessment of Sore Throat Pain at 24 Hours — 4; 4; 5 units on a scale (1 to 5) — p=<0.001
Phase 3 N=298 Dexamethasone vs Placebo in the Prophylaxis of Radiation-Induced Pain Flare Following Palliative Radiotherapy for Bone Metastases
Bone Metastases
Primary: Radiation-induced Pain Flare Incidence — 39; 53 Participants — p=0.05
Phase 4 N=140 Intravenous Dexamethasone on Supraclavicular Brachial Plexus Block for Shoulder Arthroscopy
Shoulder Arthroscopy · Pain
Primary: Duration of Analgesia From a Supraclavicular Block Performed for Shoulder Arthroscopy — 17.4; 22.7; 20.2; 19.8 Hours
Phase 3 N=26 Daily Prednisone Versus Pulsed Dexamethasone in Treatment-naïve Adult Patients With Immune Thrombocytopenia
Purpura, Thrombocytopenic, Idiopathic
Primary: Remission Duration — 3; 11 Participants
Phase 4 N=100 Dexamethasone vs Ondansetron After Cesarean Delivery
Nausea and Vomiting, Postoperative · Cesarean Section Complications
Primary: Medications Received — 0.23; 0.40 Medications
N/A N=527 DEXYCU (Dexamethasone Intraocular Suspension) 9% Retrospective Study 001
Cataract
Primary: Percentage of Eyes With Anterior Chamber Cell Grade 0 — 65 percentage of eyes