N/A N=36 Cancer Dietary Objectives Study
Cancer · Heart Disease
Primary: Dietary Quality — 38.78; 41.18; 39.76 score — p=0.14
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=24 Dietary Fat, Eicosanoids and Breast Cancer Risk
Breast Cancer
Primary: Plasma Sex Hormone Levels
N/A N=120 Healthy Eating for Colon Cancer Prevention
Colon Cancer
Primary: Adherence to Dietary Goals — 89; 85 percentage of participants meeting goals
Early Phase 1 N=7 Pharmacokinetics of Benzo[a]Pyrene: Impact of Diet
Environmental Exposure
Primary: Peak Plasma Concentration of 14C-BaP Cmax — 3.69; 1.67; 0.68 fg [14C]-BaP/mL plasma
N/A N=615 Individual Counseling and/or Computer-Based Counseling in Helping Healthy Women Adopt a Cancer Prevention Diet
Unspecified Adult Solid Tumor, Protocol Specific
Primary: Change in Fruit, Vegetable Consumption as Measured by Food Frequency Questionnaire at 3 Months — 2.7272727; 2.9758065; 2.7330645; 0.4720000 number of servings per day
N/A N=281 Oral Cell DNA Adducts in Smokers
Lung Cancer
Primary: Concentration of γ-OH-Acr-dGuo, a Major Acrolein-DNA Adduct — 49.7; 67.1; 46.5 10^9 nucleotides/mL
N/A N=297 WIC-Based Intervention to Promote Healthy Eating Among Low-Income Mothers
Cancer Prevention · Diet Modification · Vegetable Intake
Primary: Vegetable Intake Carotenoid Scores at 3 Months — 227.11; 269.98 units on a scale — p=0.001
Phase 2 N=141 Fish Oil Supplementation, Nutrigenomics and Colorectal Cancer Prevention
Colorectal Adenomatous Polyps
Primary: Rectal Epithelial Cell Proliferation — 19.3; 20.3; 18.9; 16.8 percentage of cells positive
N/A N=300 Evaluation of the Role of Aflatoxin as an Environmental Risk Factor Attributable to Liver Cancer in Nile Delta
Liver Cancer
Primary: Serum Aflatoxin Level in Liver Cancer Patients — 7.96; 6.10; 4.13 ng\ml
Phase 1 N=49 Behavioral Dietary Intervention for the Improvement of Bladder Cancer Survivorship
Stage 0a Bladder Cancer AJCC v8 · Stage 0is Bladder Cancer AJCC v8 · Stage I Bladder Cancer AJCC v8
Primary: Urinary Isothiocyanates Levels — 10.4; 4.3 mM — p=0.28
N/A N=98 Chemoprevention of Prostate Cancer, HDAC Inhibition and DNA Methylation
Prostate Cancer Prevention
Primary: Change of Total Urine SFN (Sulforaphane) Metabolites — 4.75; -0.02 micromolar (µM) concentrations of urina
N/A N=35 Fiber and Fish Oil Supplements for the Prevention of Colorectal Cancer
Healthy Subject
Primary: Feasibility and Retention for a Trial With Daily Doses of 35 g of Fiber and 6.2 g of EPA +DHA (and Corresponding Comparators) — 14; 15; 1; 1 Participants
N/A N=16 Diet Induced Intestinal Mucosal Adaptation
Healthy Conditions
Primary: Mucosal Surface Enlargement — 10.2; 9.9 percentage of muscular mucosae — p=<0.05
N/A N=70 Cook for Your Life!: Implementing Dietary Change Among Hispanic Breast Cancer Survivors
Breast Cancer
Primary: Change in Daily Servings of Fruits and Vegetables — -0.1; 2.0 daily servings of fruits and vegetables
Phase 3 N=478 Diet in Altering Disease Progression in Patients With Prostate Cancer on Active Surveillance
Prostate Cancer
Primary: Time to Progression — 683.0; 549.0 days — p=0.76
Phase 2 N=291 Broccoli Sprout Intervention in Qidong, P.R. China
Environmental Carcinogenesis
Primary: Effect of Treatment on Levels of Air Toxics Mercapturic Acids Over Intervention Period — 1.700; 1.065 pmol/mg creatinine
N/A N=23 Red and Processed Meat Effects on the Metabolome and Microbiome
Controlled Feeding Trial · Healthy Eating Index · Red Meat
Primary: Test the Effects of Red and Processed Meat on Aqueous Biomarkers of the Blood Metabolome — 0.87; 0.60; 3.48; 5.66 ratio of day 21 to day 0
N/A N=81 Correlation Between Skin Carotenoid Levels and Previous History of Skin Cancer
Skin Cancer · Basal Cell Carcinoma · Squamous Cell Carcinoma
Primary: Skin Carotenoid Levels in Subjects With History of Squamous Cell Carcinoma Versus Control Subjects — 27,635; 31,219 Raman spectroscopy intensity counts — p=0.31
N/A N=16 Metabolism of NNK in Japanese Americans
Smoking
Primary: The Ratio of D4-hydroxy Acid to D4- NNAL (an Estimate if NNK Alpha Hydroxylation) — 0.133; 0.175 Ratio
N/A N=48 Scavenging of Reactive Carbonyl Species by Dietary Flavonoids in Humans
Human Health · Reactive Carbonyl Species · Polyphenols
Primary: Change in Urinary Levels of Reactive Carbonyl Species (RCS) of Soymilk, Green Tea, or Blueberry Over 8 Hours After One Single Dose of Soymilk, Green Tea, or Blueberry…
Early Phase 1 N=49 Broccoli Sprout/Broccoli Seed Extract Supplement in Decreasing Toxicity in Heavy Smokers
Cigarette Smoking-Related Carcinoma · Tobacco-Related Carcinoma
Primary: Change in Urinary Excretion of the Mercapturic Acid of Benzene Following 4 Tablets Per Day of Avmacol — 1.16 data presented as ratio; no unit
N/A N=266 Nutritional Supplements and Hormonal Manipulations for Breast Cancer Prevention
Breast Cancer
Primary: Change in Absolute Breast Density — 65.53; 64.39; 65.08; 56.35 cm squared
Phase 3 N=2,259 Vitamin D/Calcium Polyp Prevention Study
Colorectal Cancer · Polyps · Adenomas
Primary: Colorectal Adenomas — 48.2; 44.9; 47.0; 45.7 percentage of subjects
Phase 2 N=42 Chemoprevention Trial - Anastrozole in Ductal Carcinoma In Situ (DCIS) in Postmenopausal Women
DCIS
Primary: Number of Participants With a Change in Ki-67 Level — 15; 5; 3 Participants — p=0.004
N/A N=150 Dietary Carbohydrate and GERD in Veterans
Gastroesophageal Reflux Disease · Obesity
Primary: Gastroesophageal pH — 7.3; 6.6; 3.7; 4.9 percent time ph < 4 in 24 hrs
N/A N=62 Optimizing an mHealth Intervention to Change Food Purchasing Behaviors for Cancer Prevention
Cancer
Primary: 1a. Dietary Intake: ASA24 (Fiber) — 18.45; 18.17; 15.89; 20.73 grams/day — p=.255
N/A N=4 Dietary Soy Isoflavones In Chronic Pancreatitis
Chronic Pancreatitis
Primary: Dose Limiting Toxicities — 0; 0; 0; 0 Participants
Phase 2 N=12 Novel 13C Carotenoids for Absorption and Metabolism Studies in Humans
Healthy
Primary: Plasma Half Life of Labeled Carotenoid — 6.2; 2.3 days
Early Phase 1 N=8 Benzo[a]Pyrene Ultralow Dose-Response Study
Environmental Exposure
Primary: Peak Plasma Concentration Cmax — 2.51; 5.68; 13.8; 8.99 fg [14C]-BaP/mL plasma
N/A N=61,175 Carcinogenicity Study of Bupropion
Depressive Disorder · Cancer
Primary: Number of Participants Diagnosed With Any of the Cancers Under Investigation Who Were Regularly Exposed to the Indicated Antidepressant — 853; 4561; 1963; 2570…