N/A N=541 Cesarean Section Via Enhanced Recovery
Cesarean Section
Primary: Opioid Consumption — 60.34; 104.33 oral morphine equivalents (mg) — p=< 0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=130 Enemas Before Elective Cesarean Section
Complications After Cesarean Section
Primary: Number of Participants With Bowel Sounds — 23; 31 participants — p=0.15
N/A N=1,274 Timing of Planned Caesarean Section and Morbidity of the Newborn
Respiratory Disorders · Intensive Care, Neonatal
Primary: Neonatal Admission After Elective Caesarean Section — 88; 76 participants — p=0.31
Phase 2 N=118 Enhanced Recovery at Cesarean Birth to Improve Postoperative Outcomes and Reduce Postoperative Length of Stay
Cesarean Section
Primary: Discharge on Postoperative Day #2 — 5; 2 Participants
N/A N=240 A Trial Comparing Combined Spinal- Epidural Dosing Strategies for External Cephalic Version
Pregnancy · Pain
Primary: Success Rate of External Cephalic Version — 31; 31; 31; 30 Participants
N/A N=79 Improving Cesarean Section Experience Through Hypnotherapy
Cesarean Section · Pain · Anxiety
Primary: Wellbeing Measured Using a Comfort Scale — 6.7; 8.0 units on a scale
N/A N=149 Family-Centered Cesarean Delivery
Patient Satisfaction · Earlier Family Bond Initiation · Maternal and Neonatal Outcomes
Primary: 11-item Patient Satisfaction Questionnaire — 4.6; 4.4; 4.6; 4.3 units on a scale
Phase 4 N=167 Efficacy and Safety of EXPAREL Versus Standard of Care (SoC) in Subjects Undergoing Elective Cesarean Section
Elective Cesarean Section · Pain Management
Primary: Total Postsurgical Opioid Consumption Through 72 Hours — 69.3; 36.1; 22.1 OMED mg
Phase 4 N=150 ESP Block for Post Cesarean Analgesia
Cesarean Section Complications
Primary: Postoperative Oxycodone Consumption 0- 48 Hours After Cesarean Delivery — 12.5; 25 mg
N/A N=2,804 The Twin Birth Study: A Trial Comparing Planned Vaginal Birth to Elective Caesarean Section of Twins
Twin Pregnancy
Primary: Perinatal/Neonatal Mortality and/or Serious Neonatal Morbidity — 60; 52; 24; 17 Participants
N/A N=96 Scalpel vs Diathermy in Repeat Cesarean Delivery
Complications; Cesarean Section
Primary: Incision Time . — 271.5; 188.17 Seconds — p=<0.001
N/A N=1,485 Effect of a Patient-Centered Decision App on TOLAC
Pregnancy · Repeat Cesarean Section · Vaginal Births After Cesarean
Primary: Number of Participants Who Underwent a Trial of Labor After Cesarean (TOLAC) Delivery — 315; 338 Participants
N/A N=61 CSE v. Epidural for Postpartum Depression
Depression, Postpartum · Labor Pain
Primary: Edinburgh Postnatal Depression Score (EPDS) — 4.23; 4.71 score on a scale — p=0.7463
N/A N=301 Self-Retaining Retractor in Obese Patients Undergoing Cesarean Section
Pregnancy · Obese
Primary: Wound Infection or Disruption — 38; 37 participants
Phase 2 N=53 Study of the Effect of Intramuscular Ephedrine on the Incidence of Nausea and Vomiting During Elective Cesarean Section
Nausea · Vomiting · Cesarean Section
Primary: Pre-Induction Nausea Score — 0.067; 0 units on a scale
Phase 4 N=602 Prophylactic Ephedrine and Combined Spinal Epidurals for Labor
Labor Pain
Primary: Early Profound Fetal Bradycardia — 8; 14 participants — p=0.18
N/A N=40 Opportunistic Salpingectomy for Permanent Sterilization at the Time of Cesarean Delivery
Contraception
Primary: Mean Difference Between Pre and Postoperative Hemoglobin (g/dl) — 1.4; 1.8 g/dL — p=0.08
N/A N=2,013 Study of Effectiveness and Safety of Azithromycin-based Extended-spectrum Prophylaxis to Prevent Post Cesarean Infection
Endometritis · Wound Infection · Abscess
Primary: Participants With Endometritis and/or Wound Infection and/or Other Post-cesarean Infections (Occurring Within 6 Weeks of Delivery) — 119; 62 Participants
N/A N=136 PROphylactic Wound VACuum Therapy to Decrease Rates of Cesarean Section in the Obese Population
Wound Complication
Primary: Number of Participants With Wound Complications — 3; 4 Participants
N/A N=140 Dural Puncture Epidural Versus Epidural Anesthesia for Cesarean Delivery
Pain Levels
Primary: Onset Time of Surgical Anesthesia — 422; 655 seconds
N/A N=168 Short Term Comparison of Two Different Techniques of Uterine Cesarean Incision Closure
Cesarean Section Complications
Primary: Cesarean Scar Defect in the Uterine Incisional Line — 12; 39 participants — p=0.0001
N/A N=384 Role of Membrane Sweeping on Initiation of Labor and Vaginal Birth in Previous Cesarean Section
Vaginal Birth After Cesarean Section
Primary: Number of Participants With Onset of Labor by 40 Weeks — 119; 90 participants
N/A N=168 Long Term Comparison of Two Different Techniques of Uterine Cesarean Incision Closure
Cesarean Section; Complications · Placenta Previa · Placenta Accreta
Primary: Placenta Previa — 18; 17; 0; 3 Participants
N/A N=66 Should I Have an Elective Induction?
Labor, Induced · Patient Preference
Primary: Recruitment Rate — 66 Participants
N/A N=78 Randomized Control Trial of Second Stage of Labor
Labor Complications
Primary: Number of Patients Delivered by Cesarean — 16; 8 Participants
N/A N=80 Modifying Cervical Bishop Scoring System
Failed Induction of Labor
Primary: Area Under Receiver Operating Characteristic Curve (ROC) for Modified Bishop Score — 0.916 probability — p=0.000
N/A N=92 The Use of the Prevena™ Incision Management System on Post-Surgical Cesarean Section Incisions
Post-operative Complications · Surgical Site Infection · Surgical Wound Infection
Primary: Incidence of Postoperative Surgical Site Occurrences (SSOs) up to Day 42 (+/- 10 Days) Post Cesarean Section Surgery. — 7; 2 participants
N/A N=69 High Pain Intervention in Cesarean Sections
Other Chronic Postoperative Pain
Primary: Severity of Acute Pain — 46; 31 mm — p=0.05
N/A N=134 TrueRelief Efficacy for Post-cesarean Pain (ELECTRON)
Post-cesarean Pain
Primary: Median of Total Inpatient Oral Opioids Consumption (in Morphine Milligram Equivalents) in Treatment With TrueRelief Device Versus Sham Comparator Groups. — 19.75; 37.50…
Phase 4 N=60 Oxytocin And Uterotonic Agent Use For Cesarean Delivery
Uterine Atony · Hypotension
Primary: 1. Amount of Oxytocin to Obtain Satisfactory Uterine Tone. — 8.4; 4.0 IU