Clinical Trial Search

Primary: Insulin Sensitivity as Measured by Hyperinsulinemic Euglycemic Clamp at a Single Time Point (6 Hrs) After Intralipid or Glycerol Infusion — 8; 12; 6; 11 M value — p=<0.05

Primary: Percent Change in Forearm Glucose Uptake — -73; 127; -95 Percent change in clamp FGU with immob

Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared

Primary: Fat Mass — 44.71 Kg

Primary: Change in 1-repetition Maximum (RM) Muscle Strength (Leg Press, Paretic Side) — 126.1; 11.3 lbs

Primary: Appendicular Non-bone Lean Mass — -2.53; -2.49; -2.04; -1.45 kg

Primary: Correlation Between Knee Flexor Muscle Modified Ashworth Scale and Insulin Resistance — -0.692; 0.23 correlation coefficient — p=0.006

Primary: Whole-Muscle Protein Synthesis — 0.004; 0.015 %/hr

Primary: An Outcome of This Study is the Difference in Percent Body Fat (%BF) Between Subjects With a Long-chain Fatty Acid Oxidation Disorder and Normal Controls. — 31.8; 27.2…

Primary: Pancreatic and Liver Triglyceride (Fat) Content — 6.44; 2.08 percent

Primary: Change in Liver Fat — 0.03 Lipid/water ratio

Primary: Pancreatic and Liver Fat — 1.87; 6.57; 3.61; 5.85 percent

Primary: Change in Fat mtDNA Content — -169; 321 copies/cell

Primary: Brachial Artery Vascular Function — 5.1; 3.1; 4.4 percent vasodilation

Primary: Visceral Fat Loss (cm3) — -628 cm3

Primary: Safety Outcomes: Frequency of Adverse Events — 49; 24; 42 Total Number of Adverse Events — p=0.06

Primary: Collection of Imaging of BAT by Magnetic Resonance Imaging — 78.69; 82.58; 82.45 Percentage

Primary: Hepatic Insulin Sensitivity Index (HISI) — 0.8; 1.4 [10000/(μmol/min)x(mU/L)] — p=<0.019

Primary: Acute Gene Regulation: MSTN — 5.49; 4.76 arbitrary units — p=<0.001

Primary: Efficacy of Autologous Fat Transfer at Pain Modulation at Respective Amputation Sites — 1.3; 0 score on a scale

Primary: Skeletal Muscle Capillarization — 0.4; 0.2 capillaries per muscle fiber — p=0.27

Primary: Change in Respiratory Quotient (RQ) — -0.0552; 0.00453 ratio

Primary: Change in Limb Fat (g) From Baseline — 74; 110 grams — p=0.64

Primary: Change in Circulating Glucagon-like Peptide-1 (GLP-1) Levels — 7147; 11725; 11898; 28060 pM*min

Primary: In Vivo Adipose Cell Formation (Adipogenesis) — -0.3; 1.8; -1.2; 2.1 percent

Primary: Median Change in Visceral Adipose Tissue (VAT) Volume — -4.6 cm^2

Primary: Change in Lean Mass Measured by DXA — -2.9; -2.3 Kg

Primary: Mitochondrial Function (mtDNA Levels) — 1372 copies per cell

Primary: MRI Quadriceps Involved Leg — 43.87; 38.31 AU — p=.03

Primary: Percent Change in Serum Myostatin Levels From Pre- to 3 Hours Post-exercise — -6.9; 8.5 % change in serum myostatin — p=0.303