N/A N=11 IVF Hyper-responders: Oocyte Vitrification Compared With Embryo Freezing
Infertility
Primary: Fetal Heart Activity 1 Month Post Embryo Transfer — 0; 4 participants with fetal heart activity
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=349 In Vitro Fertilization Impact on Metabolic Parameters
GDM · Insulin Resistance · Glucose Intolerance
Primary: Short-term Effect of Fertility Medications on Glucose Homeostasis and Insulin Resistance in Patients Undergoing IVF Treatment — 87.62; 82.19; 9.37; 9.45 mg/dL
Phase 2 N=265 A Dose-response Trial Using rFSH FE 999049 in Women Undergoing IVF/ICSI Treatment
Infertility
Primary: Number of Oocytes Retrieved — 5.2; 7.9; 9.2; 10.5 Oocytes — p=<0.001
Phase 4 N=112 Multicenter, Randomized, Open Label, Parallel Study to Evaluate the Efficacy & Safety of IVF-M HP Inj. vs. Menopur® Inj.
Infertility, Female
Primary: Number of Retrieved Oocytes — 13.14; 10.29 Oocytes
Phase 2 N=175 The Use of the Hormone Kisspeptin in 'in Vitro Fertilisation' (IVF) Treatment
Infertility
Primary: Percentage of Oocyte Maturation — 49; 36; 76; 103 percentage of expected oocyte yield — p=<0.05
Phase 3 N=215 Convenience and Safety of Assisted Reproductive Technology Procedures Using a Gonal-F Filled by Mass (Fbm) Liquid Formulation Applied by Pen for Ovulation Induction and In-vitro Fertilization
Infertility · Ovulation Induction · In-Vitro Fertilization
Primary: Number of Subjects Who Self-administered the Investigational Medicinal Product (IMP) — 159 subjects
Phase 3 N=52 A Prospective Study to Evaluate the Addition of Subcutaneous Recombinant Human-Luteinizing Hormone With Recombinant Human-Follicle Stimulating Hormone on Follicular Development in Women Undergoing Ovarian Stimulation for Assisted Reproductive Technologies
Infertility · Ovarian Stimulation
Primary: Mean Number of Metaphase II Oocytes Per Participant Who Underwent Ovum Pick up for Intra-cytoplasmic Sperm Injection (ICSI) — 9.5 Metaphase II Oocytes
Phase 3 N=1,390 Frozen-thawed Embryo Transfer (FTET) Cycle Follow-up Protocol (P06031)
Infertility
Primary: Percentage of Participants With ≥1 Vital Pregnancy (Cumulative Vital Pregnancy Rate) — 31.1; 33.0 Percentage of Participants
N/A N=97 The Impact of Distress on the IVF Outcome
Infertility
Primary: Clinical Pregnancy Rates — 20; 52 percentage of participants
Phase 4 N=23 Maximal Stimulation and Delayed Fertilization for Diminished Ovarian Reserve: a Randomized Pilot Study
Infertility
Primary: Oocytes — 19; 47 oocytes
N/A N=1,467 The Application of Zishen Yutai Pill in Aged Women Undergoing IVF-ET
Infertility, Female
Primary: Live Birth Rate — 171; 139 Participants — p=0.042
Phase 4 N=90 Effects of Intrauterine Flushing With Human Chorionic Gonadotropin on ICSI Outcome
Female Infertility
Primary: Serum Level of TNF-alfa,IL-10, for All Participants in Three Study Group at Day of Ova Pickup Compared to That at Day of Embryo Transfer — 43.56; 41.59; 40.94; 30.33 pg/ml
Phase 2 N=520 Investigation of a Long-Acting Follicle Stimulating Hormone in Infertile Women Undergoing Assisted Reproductive Technology (ART)
Infertility
Primary: Number of Fertilized Oocytes (2 Pronuclei [PN]) — 7.0; 8.7; 9.2; 6.7 2PN oocytes
N/A N=386 Sperm Selection by Microfluidic Separation Improves Embryo Quality
Sperm DNA Fragmentation · Embryo Quality · Fertility Disorders
Primary: Day 3 High Quality Embryo Percentage — 68; 66 percentage of high quality embryos
Phase 3 N=1,332 Efficacy Study of Granulocyte-macrophage Colony Stimulating Factor (GM-CSF) for Use in Human IVF
Infertility
Primary: Ongoing Implantation Rate Week 7 — 23.5; 20.0 percentage of transferred embryos
Phase 2 N=129 Effect of Colony Stimulating Factor on Implantation and Pregnancy Rates Following IVF (in Vitro Fertilization)
Infertility, Female
Primary: Embryo Implantation and Clinical Pregnancy Rates — 32; 33 Gestational sacs — p=0.72
N/A N=1,066 eValuating iDA Selection Ability. The VISA Study.
IVF · Infertility
Primary: Clinical Pregnancy Rate — 257; 248 Participants
Phase 4 N=468 Comparison of Crinone 8% Intravaginal Gel and IM Progesterone Supplementation for In Vitro Fertilization (IVF)
Infertility
Primary: Percentage of Pregnant Patients After IVF Treatments — 66; 62 percentage of participants — p=<0.05
Phase 4 N=3 Ovulation Trigger With hCG Compared to GnRH Agonist in Patients With Repeated IVF Failures
Infertility
Primary: Fetal Heart Activity 1 Month After Oocyte Retrieval — 0; 0 participants with fetal heart activity
Phase 3 N=27 Immunogenicity of Repeated Follicle Stimulating Hormone (FSH) Stimulation Cycles
Oocyte Donation
Primary: Number of Patients Producing Anti-FSH Antibodies. — 0 participants
N/A N=100 SIS Versus Office Hysteroscopy for Uterine Cavity Evaluation Prior to IVF
Infertility
Primary: Patient Satisfaction — 4.92; 4.84 units on a scale — p=0.57
Phase 3 N=151 Efficacy and Tolerability of Human FSH Versus Recombinant FSH (Follitropin Alpha) in ICSI.
Infertility
Primary: Total Number of Oocytes Retrieved — 10.9; 12.0 oocytes
Phase 3 N=1,031 A Multicenter Study Comparing the Efficacy, Safety and Tolerability of Oral Dydrogesterone 30 mg Daily Versus Intravaginal Micronized Progesterone Capsules 600 mg Daily for Luteal Support in In-Vitro Fertilization
Female Infertility
Primary: Percentage of Participants Being Pregnant as Measured by the Presence of Fetal Heart Beats at 12 Weeks´Gestation Using Transvaginal Ultrasound — 37.6; 33.1 percentage of…
N/A N=739 Impact of Sperm DNA Integrity on In Vitro Cycles
Male Infertility · Unexplained Infertility · Abortion, Habitual
Primary: Pregnancy — 67; 80 participants
Phase 3 N=105 Administration of Follicle-stimulating Hormone (FSH) and Low Dose Human Chorionic Gonadotropin (hCG) for Oocyte Maturity While Decreasing hCG Exposure in In Vitro Fertilization (IVF) Cycles
Infertility
Primary: Total Fertilization Proportion (i.e. Total Competent Proportion) — 0.59; 0.65 ratio
N/A N=335 Embryo Transfer With Self-spent Culture Medium
in Vitro Fertilization
Primary: Number of Participants Pregnant After 4 Weeks — 85; 82 Participants
Phase 4 N=124 Progesterone Serum Levels in Subfertile Female Patients Undergoing in Vitro Fertilisation (IVF)
Infertility
Primary: Serum Progesterone (P4) Level in the Morning of the Day of Human Chorionic Gonadotrophin (hCG) Administration — 0.69; 0.72; 0.54; 0.89 ng/ml — p=0.003
Phase 3 N=588 Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-2)
Infertility, Female
Primary: Cumulative Ongoing Pregnancy Rate After the Fresh Cycle and Cryopreserved Cycles Initiated Within 12 Months From the Start of Controlled Ovarian Stimulation (COS)…
N/A N=77 Intravenous Immunoglobulin (IVIG) for Treatment of Unexplained Secondary Recurrent Miscarriage
Miscarriage, Recurrent · Abortion, Habitual
Primary: Number of Successful Pregnancies Defined as an Ongoing Pregnancy Over 20 Weeks Gestation, Per Number of Index Pregnancies — 16; 15 Successful pregnancies — p=<0.05
Phase 3 N=1,100 Phase III Study Comparing Efficacy and Safety of AFOLIA vs Gonal-f® RFF in Women (35 to 42) Undergoing IVF
Infertility
Primary: Clinical Pregnancy Rate After One Cycle of Treatment - ITT Population — 114; 138; 435; 413 Participants