Clinical Trial Search

Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline

Primary: Number of Participants With Viable Specimens for Genetic Analysis — 14 participants

Primary: Pain Sensitivity: Pressure Pain Detection Threshold (PPT) — 252.58; 266.17 kPa

Primary: Change Form Baseline in WOMAC A Pain Subscale — -11.14; -11.82 cm — p=<0.025

Primary: Change of External Knee Adduction Moment as Assessed by Visual Motion Analysis System — 0.50 Nm/kg

Primary: Cross-sectional Area (CSA) of Muscle Fibers — 2680; 2377; 2028; 1882 micron squared

Primary: Summary of Adverse Events — 2; 2; 3; 2 Adverse events

Primary: Patient Function (Units on a Scale) — 31 units on a scale

Primary: Change From Baseline to Week 17 and From Baseline to Week 21 in Pain as Measured by Numerical Rating Scale — -2.1; -1.8; -2.2; -1.5 units on a scale — p=0.495

Primary: Change in International Knee Documentation Committee (IKDC) Subjective Knee Form Score — 22.2; 20.6 units on a scale

Primary: Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) — -4.85; 0.26; -3.97; -2.53 units on a scale — p=0.0003

Primary: Medial Condylar Separation With Brace — 0.60 mm

Primary: Change in Knee Injury and Osteoarthritis Outcome Score (KOOS) — 3.3; 8.9; 4.6; 9.7 score on a scale — p=<0.05

Primary: Change in Basic Lower Limb Function (Late Life Function Index) Late Life Function and Disability Instrument — 3.3; -1.0; 3.1; 0.8 units on a scale

Primary: Pain When Walking On A Flat Surface — 0; 1; 8; 4 Participants

Primary: Change From Baseline in WOMAC VA3.1 Pain Subscale Score at Month 6 — -23.6; -14.1 mm — p=0.141

Primary: Change in Cellular Infiltrates From Day 0 to Day 28 — 2; 0; 2; 4 Participants

Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) — 61.91; 72.59; 71.17; 85.99 score on a scale

Primary: Composite Clinical Success (CCS) — 83.5; 57.2 percentage of subjects

Primary: T1rho Relaxation Times in the Medial Femoral Condyle at Baseline — 53.48 ms

Primary: Knee Pain During a Single Leg Squat — 5.6; 5.2; 4.1; 3.4 units on a scale

Primary: Change From Baseline in the International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Score at 1 Year — 23.3; 9.9 scores on a scale — p=<0.01

Primary: Pain on the Numeric Rating Scale (NRS) Change From Baseline to Study Conclusion — -1.96; -0.85 units on a scale

Primary: Change in Medial Knee Contact Forces During Walking — -0.04 bodyweights

Primary: Change in Lower Extremity Function — 10.6; 7.6; -6.4 Change in scores on a scale

Primary: Differences in Decision Conflict Scale With ASK vs Usual Care — 25.1; 26.0 Score on a scale

Primary: Quadriceps Muscle Force — 1.27; 1.37; 0.79; 0.66 Nm/kg — p=0.07

Primary: Group 2 - Total Knee Society Score (KSS) — 92.2; 78.5; 118.2; 96.7 score on a scale

Primary: WOMAC Functional Status - Difference From Baseline — 20.9; 18.5 Score — p=0.26

Primary: Percentage of Participants With Composite Clinical Success (CCS) — 83.5; 57.2 percentage of subjects