Phase 3 N=53,454 National Lung Screening Trial (NLST) Screening
Lung Cancer
Primary: Lung Cancer Deaths — 356; 443 Participants — p=0.004
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=79 Empowering Patients' Lung Cancer Screening Uptake
Lung Cancer
Primary: Order of LDCT — 50 Participants
N/A N=80 Testing Informed Decision Making in Lung Cancer Screening
Lung Cancer
Primary: Number of Patients Who Received a Low Dose CT Scan of the Chest — 18 Participants
N/A N=242 Community Support Program for Lung Cancer Screening
Lung Cancer · Behavior
Primary: Percentage of Scheduled Lung Cancer Screening Appointments Attended by Participants — 88; 68; 64 % of lcs appointment attendance
N/A N=1,219 Evaluation of a Scalable Decision Support and Shared Decision Making Tool for Lung Cancer Screening
Early Detection of Cancer · Lung Neoplasms
Primary: Number of Participants With Lung Cancer Screening (LCS) Care-Gap Closed — 588 Participants
N/A N=6,125 Lung Cancer Screening Eligibility Assessment
Lung Cancer
Primary: Full Survey Completion — 358; 381; 383; 389 Participants
N/A N=140 Incorporating Veterans' Preferences Into Lung Cancer Screening Decisions
Lung Cancer Screening
Primary: Decisional Conflict — 25.7; 29.9 units on a scale — p=0.18
N/A N=1,200 Patient Navigation for Lung Screening at MGH Community Health Centers
Lung Cancer
Primary: Chest CT Completion — 124; 138 Participants
N/A N=41 Tobacco Treatment in the Context of Lung Cancer Screening
Smoking Cessation
Primary: End of Treatment Abstinence Rates — 3; 0 Participants
N/A N=39 Low-Dose Chest Computed Tomography Screening for Lung Cancer in Survivors of Hodgkin's Disease
Lung Cancer
Primary: To Prospectively Collect Data on Chest CT Screening for Patients at Increase Lung-cancer Risk After Hodgkin's Disease. — 0 participants
N/A N=516 PCORI-CER-1306-03385 Informed Decisions About Lung Cancer Screening
Lung Cancer · Smoking Cessation · Tobacco Use Cessation
Primary: Mean Value: Preparation for Decision Making© Scale — 79.4; 69.4 units on a scale
N/A N=944 Promoting Smoking Cessation in Lung Cancer Screening Through Proactive Treatment
Smoking Reduction · Tobacco Use · Tobacco Smoking
Primary: Self-reported Smoking Abstinence — 50; 51 Participants — p=0.83
Phase 2 N=367 Gain-framed Messages and NRT for Lung Cancer Screening Patients
Lung Cancer Screening · Smoking Cessation
Primary: Smoking Cessation - Available Data — 15; 19 Participants
N/A N=97 Assessing Social Determinants of Health to Increase Cancer Screening
Lung Cancer
Primary: Lung Cancer Screening Uptake — 1; 5 Participants
N/A N=31,303 The MyLungHealth Study Protocol: Engaging Patients to Enable Interoperable Lung Cancer Decision Support at Scale
Lung Cancer · Lung Neoplasms/Diagnosis
Primary: Study 1 Primary Outcome: Count of Patients Newly Identified as Eligible for Lung Cancer Screening — 308; 635 Participants
N/A N=1,422 Digital Outreach Intervention for Lung Cancer Screening
Lung Cancer
Primary: Number of Participants With Electronic Health Record-verified Completion of a Chest CT Scan — 164; 113 Participants
N/A N=50 Evaluation of the Lung Nodule Sensitivity of Stationary Chest Tomosynthesis in Patients With Known Lung Nodules
Signs and Symptoms
Primary: Sensitivity — 53 percentage of positive scans
N/A N=252 Community Support Program for Lung Cancer Screening Volume II
Lung Cancer
Primary: Scheduled Lung Cancer Screening Appointments Attended by Participants — 21; 65; 59 Participants
Phase 4 N=642 Assessing the Integration of Tobacco Cessation Treatment Into Lung Cancer Screening (LCS)
Smoking, Tobacco
Primary: Number of Participants With Self-reported Past 7-day Smoking Abstinence — 12; 10; 12; 15 Participants
N/A N=260 Lung Cancer Screening Navigation for Homeless People
Lung Cancer · Tobacco Use · Homelessness
Primary: Number (Percentage) of Participants Who Receive Low-dose Computed Tomography (LDCT) for Lung Cancer Screening (LCS) at 6 Months (26 Weeks). — 8; 75 Participants — p=<0.001
N/A N=654 DECIDE: Developing Tools for Lung Cancer Screening Discussion Improvement
Smoking · Smoking, Tobacco · Smoking, Cigarette
Primary: Key Components of Shared Decision Making Process That Predict Patient-perceived Lung Cancer Screening Decision Quality — 21.5 score on a scale
N/A N=102 Tailoring Shared Decision Making for Lung Cancer Screening in Persons Living With HIV
Lung Carcinoma
Primary: Focus Group Analysis (Aim I) — 43 Participants
N/A N=76 National Comprehensive Cancer Network (NCCN) Decision Support Tool for Patients With NSCLC
Non-small Cell Lung Cancer
Primary: Percentage of Participants Reporting Quality of Care on Selected National Comprehensive Cancer Center (NCCN) Recommendations — 80; 0; 50; 28.6 percentage of participants
N/A N=20 Tele-Navigation of Lung Cancer Screening (Tele-Navi LCS)
Lung Cancer
Primary: Completion of Tele-Navi LCS — 20 Participants
N/A N=120 Shared Decision Making in Rural Primary Care Lung Cancer Screening and Smoking Cessation
Lung Cancer · Smoking Cessation
Primary: Count of Participants Who's Health Visit Adhered to the LCS Guidelines and CMS Coverage Criteria in Rural Primary Care Practices: Baseline Survey — 0; 0 participants
Phase 2 N=92 Pioglitazone for Lung Cancer Chemoprevention
Lung Cancer · Endobronchial Dysplasia
Primary: 6-month Histology Score — 3.07; 3.71 Units on a scale — p=0.53
N/A N=9 Designing an Implementation Strategy for Lung Screening and Smoking Cessation Treatment in Community Health Centers
Smoking Cessation
Primary: Feasibility of Intervention Measure — 4 units on a scale
N/A N=25 Sputum Labeling Utilizing Synthetic Meso-Tetra (4-Carboxyphenyl) Porphine (TCPP) for Detection of Lung Cancer
Lung Cancer
Primary: Number of Red Fluorescent [i.e., Cancer] Cells (RFCs) in Sputum From Healthy Participants — 0 number of RFCs per participant
Phase 2 N=22 Hyperpolarized Xenon Gas MR Imaging in NSCLC Radiotherapy
Non-small Cell Lung Cancer
Primary: Number of Participants With a Change From Baseline in Ventilation Map Using Hyperpolarized Xe-129 MR Imaging — 6 Participants — p=0.041
N/A N=3,228 Comparing Smoking Cessation Interventions Among Underserved Patients Referred for Lung Cancer Screening
Smoking Cessation
Primary: Biochemically Confirmed Smoking Abstinence Sustained for 6 Months — 26; 45; 78; 61 Participants — p=0.797