N/A N=30 Memory Consolidation in Pharmacologically Enhanced Naps
Sleep
Primary: Pharmacological Enhancement of Specific Sleep Parameters — 3; 1 sleep spindles
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=33 Memory Consolidation in Obstructive Sleep Apnea
Obstructive Sleep Apnea
Primary: Overnight Change in Declarative Memory Performance — 11.2; 6.5 percent change in performance
N/A N=194 The Impact of Reactivation During Sleep on the Consolidation of Abstract Information in Humans
Memory Consolidation
Primary: Structure Knowledge for a New Modular Category in Stage 2 — 0.563; .5726; .6303; .6266 Proportion of correct responses
N/A N=58 Sleep and Emotional Memory in Peripubertal Anxiety
Anxiety
Primary: Scores on the Lure Generalization Index (a Behavioral Measure of Generalization) — .24; .26; .14; .10 units on a scale — p=<.046
N/A N=81 Memory and Fear Study (Fear of Memory Loss Study)
Anxiety and Fear
Primary: Fear and Avoidance of Memory Loss (FAM) Scale Score at Follow-up — 63.9; 60.3 score on a scale
Phase 1 N=92 Memory & Conditioning Under Anesthesia
Anesthesia · Pain
Primary: Explicit Memory Performance — 1.16; .51; 1.04; .98 units on a scale
N/A N=11 Effects of Gamma-tACS on Memory and Sleep
Transcranial Alternating Current Stimulation · Aging · Cognitive Decline
Primary: Percent of Participants Tolerating Cognitive Testing During tACS — 100; 100 percentage of participants
Phase 4 N=23 A Psychophysiologic Study of Weakening Traumatic Combat Memories With Post-Reactivation Propranolol
Posttraumatic Stress Disorder
Primary: Physiological Posterior Probability of Posttraumatic Stress Disorder (PTSD) as Determined From Psychophysiologic Responses During Script-Driven Traumatic Memory…
N/A N=59 Mnemonic Strategy Versus Spaced Retrieval Training in Those With Mild Cognitive Impairment
Mild Cognitive Impairment
Primary: Percent of Correct Object Location Associations Assessed up to 1 Month Post-treatment — 80.0; 62.45 percent correct — p=<.001
Phase 2 N=113 Nutraceutical Effects on Long-Term Memory
Aging
Primary: Delay Eyeblink Conditioning — 52.32; 56.88 percentage of conditioned responses
N/A N=107 Promoting Adaptive Neuroplasticity in Mild Cognitive Impairment
Mild Cognitive Impairment · Alzheimer's Disease
Primary: Face-name Memory Test Performance — -.28; -.01; -1.29; -1.76 pairs correctly recalled/recognized
N/A N=90 The Effects of Mixed Working Memory Training on Subsequent Training Gains Among Older Adults
Cognitive Aging
Primary: Change in Overall Working Memory — 0.42; 0.26; -0.01; 0.04 Standard unit change — p=0.355
N/A N=101 Water-based Activity to Enhance Recall in Veterans
Mild Cognitive Impairment
Primary: Retention and Recruitment Rates — 21 Participants
N/A N=108 Better Memory With Literacy Acquisition Later in Life
Memory Impairment
Primary: Episodic Memory Improvement — 31.8; 31.3 score on a scale — p=0.531
N/A N=48 Sleep Quality and Amyloid-Beta Kinetics
Amyloid-beta
Primary: Difference in Amyloid-beta (Abeta) Concentration in the CSF (Cerebral Spinal Fluid) of Individuals With Poor Sleep Efficiency Compared to Those With Good Sleep…
N/A N=156 A Mobile Informatics Solution to Aid in Memory
Alzheimer Disease · Dementia
Primary: PWMC Loneliness — 4.90; 5.28 units on a scale
Phase 2 N=31 Memory and Insulin in Early Alzheimer's Disease
Alzheimer's Disease
Primary: fMRI Measure of Hippocampal Activation — 36.4; 41.3 percentage of active voxels
N/A N=5 Memory and Attention Adaptation Training-Geriatrics (MAAT-G)
Cancer-related Problem/Condition · Cognitive Impairment
Primary: System Usability Scale (SUS) — 90.6 score on a scale
N/A N=20 Neuropsychological Rehabilitation of Spontaneous Confabulation
Memory Disorders
Primary: Number of Confabulations — 30.0; 29.9; 8.1; 35.5 Confabulations
N/A N=50 Wayfinding Intervention in High-Fidelity Long-Term Memory
Long-Term Memory Decline · Mild Cognitive Impairment
Primary: MDT Change in Mnemonic Discrimination — 0.09; 0.01 LDI score on a scale — p== 0.016
Phase 3 N=74 Memory Reconsolidation Blockade as a Novel Intervention for Nicotine Dependence
Smoking Cessation
Primary: Change in the Skin Conductance Level, Caused by Smoking Cues, Measured Using Script Driven Imagery — 0.107; -0.040 µS — p=0.05
N/A N=36 Modulation of CSF Amyloid-beta Concentrations Via Behavioral Sleep Deprivation and Pharmacological Sleep Induction
Amyloid-beta
Primary: Percent Increase From Mean Baseline (07:00 to 19:00) of Cerebrospinal Fluid (CSF) Amyloid Beta During Sleep Induction and Sleep Deprivation Between 01:00 and 11:00 From…
N/A N=68 Everyday Memory Intervention
Aging
Primary: Everyday Memory Failures — 0.55; 0.62 average daily number memory failures/day — p=.67
N/A N=184 Oscillatory Contributions to Working Memory and Attention
Young Adults
Primary: Behavioral Accuracy: Sub-study 1 — 86.3; 87.1 percentage of correct responses
N/A N=89 Targeting Reconsolidation to Prevent Return of Fear
Fear of Flying
Primary: Fear of Flying Inventory (FFI) — 65.55; 76.57 units on a scale
N/A N=142 Memory and the Hippocampus in Twins
PTSD · Stress Disorders, Post-Traumatic
Primary: Neuropsychological Testing of Memory — 77; 82 percentage of WMS retention
N/A N=45 Investigating the Neural Correlates in Memory Retrieval After HD-tDCS
Healthy Adults
Primary: Recognition Memory Assessed by a Retrieval Memory Experiment — 48.47; 34.78; 33.983 percentage of correctly recalled old fac
Phase 4 N=34 Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) Treatments
Post-traumatic Stress Disorder
Primary: Physiological Posttraumatic Stress Disorder (PTSD) Probability as Determined From Psychophysiologic Responses to Traumatic Recollection — 44; 45 percent probability
N/A N=68 Mild Cognitive Impairment and Obstructive Sleep Apnea
Obstructive Sleep Apnea · Mild Cognitive Impairment
Primary: Hopkins Verbal Learning Test-Revised (HVLT-R) — 23.52; 20.04; 23.68; 20.39 score on a scale
N/A N=107 Cognitive Training and Neuroplasticity in Mild Cognitive Impairment
Mild Cognitive Impairment · Memory Disorders · Memory Impairment
Primary: Change in the Alzheimer's Disease Assessment Scale-Cognitive (ADAS-Cog) — -0.89; 0.55 score