N/A N=351 Comparing Surgery Versus Standard Physical Therapy in Treating People With a Meniscal Tear and Osteoarthritis
Osteoarthritis
Primary: WOMAC Functional Status - Difference From Baseline — 20.9; 18.5 Score — p=0.26
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=146 Arthroscopy in the Treatment of Degenerative Medial Meniscus Tear
Osteoarthritis, Knee
Primary: The Lysholm Knee Score — 82.2; 83.4 units on a scale
N/A N=30 Study of Suture Repair of Torn Meniscus in the Knee
Meniscal Tear · Meniscus Tear
Primary: Freedom From Re-operation of the Index Meniscus Repair Site (Incidence of Subjects Requiring Re-operation) — 26; 1; 23; 2 Participants
N/A N=140 Surgical or Exercise Therapy on Patients With Degenerative Meniscus Tears
Degenerative Meniscal Tear
Primary: KOOS4 - Change From Baseline — 24.4; 25.3 units on a scale — p=<0.05
Phase 2 N=20 Autologous, Micro-fragmented Adipose Tissue for Meniscal Tears
Tibial Meniscus Injuries · Osteoarthritis, Knee
Primary: Change in Numerical Pain Scale — -3.2 units on a scale
N/A N=16 Prospective Trial of Arthroscopic Meniscectomy for Degenerative Meniscus Tears
Meniscus Tear
Primary: WOMET Score — 57.5; 99.4; 37.0; 63.9 units on a scale
Phase 3 N=144 Superiority of MACI® Versus Microfracture Treatment in Patients With Symptomatic Articular Cartilage Defects in the Knee
Articular Cartilage Defect
Primary: Change From Baseline to Week 104 for the Participant's Knee Injury and Osteoarthritis Outcome Score (KOOS) Pain and Function (Sports and Recreational Activities) Scores…
N/A N=27 Muscle Weakness and Post-traumatic Knee OA
Meniscectomy
Primary: Change in International Knee Documentation Committee (IKDC) Subjective Knee Form Score — 22.2; 20.6 units on a scale
N/A N=101 Role of Bone in Knee Osteoarthritis (OA)
Osteoarthritis, Knee
Primary: Number of Participants With Viable Specimens for Genetic Analysis — 14 participants
N/A N=113 MiACLR: Michigan Initiative for Anterior Cruciate Ligament Rehabilitation
Anterior Cruciate Ligament Injury
Primary: Immediately Post NMES+ECC Intervention Isokinetic Quadriceps Strength Index — 60.9; 58.4 Percentage — p=.025
Phase 2 N=49 Early Treatment for Acute ACL Tear
Anterior Cruciate Ligament (ACL) Tears
Primary: Participant Pain Assessment — -3.9; -2.2; -3.6; -4.3 units on a scale — p=0.33
N/A N=14 Spring Loaded Tri-Compartment Unloader Knee Brace Study
Anterior Knee Pain
Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) — 61.91; 72.59; 71.17; 85.99 score on a scale
N/A N=9 Clinical Application of BioCleanse Meniscus
Tear of Meniscus of Knee
Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) — 70.1 units on a scale — p=0.06
Phase 3 N=118 RCT of ChondroCelect® (in an ACI Procedure) vs Microfracture in the Repair of Cartilage Defects of the Knee
Articular Cartilage Lesion of the Femoral Condyle
Primary: Histomorphometry Safranin-O + Anti-Collagen II Antibody Staining — 1.01; 0.75 Ratio — p=0.003
N/A N=10 A Biologic Joint Replacement Strategy to Treat Patients With Severe Knee Trauma and Post-Traumatic Knee Osteoarthritis
Post-traumatic Osteoarthritis
Primary: Visual Analogue Scale Pain Score — 2.3 units on a scale
N/A N=24 Effects of Unloader Bracing in Clinical Outcome and Cartilage Physiology Following Microfracture of Chondral Defects
Cartilage Loss · Microfracture
Primary: Knee Injury and Osteoarthritis Outcome Score (KOOS) (Clinical Outcome) — 12.0; 4.1; 19.1; 8.1 units on a scale — p=0.162
N/A N=23 In Vivo Three-Dimensional Determination of Osteoarthritis Brace Effectiveness
Osteoarthritis, Knee
Primary: Medial Condylar Separation With Brace — 0.60 mm
N/A N=34 Optimizing Movement After Anterior Cruciate Ligament Injury
Anterior Cruciate Ligament Injuries · Knee Osteoarthritis
Primary: Knee Flexion Moment Impulse — 0.54; 0.50 Ratio — p=0.293
Phase 2 N=102 Study of TG-C in Patients With Grade 3 Degenerative Joint Disease of the Knee
Osteoarthritis, Knee
Primary: Change From Baseline in the International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Score at 1 Year — 23.3; 9.9 scores on a scale — p=<0.01
N/A N=150 Initial Graft Tension and ACL Surgery
Anterior Cruciate Ligament Rupture
Primary: Radiographic Joint Space Narrowing (Midpoint Method) — 0.0613; 0.0634; -0.0321; 0.1374 mm — p=.27
N/A N=99 Time-dependent Improvement of Functional Outcome Following Oxford Medial Unicondylar Knee Replacement
Osteoarthritis
Primary: Knee Injury and Osteoarthritis Outcome Score — 85.5; 88.2 units on a scale
N/A N=80 Trial Comparing BST-CarGel and Microfracture in Repair of Articular Cartilage Lesions in the Knee
Knee Injuries
Primary: Degree of Filling of the Lesion by Repair Tissue at 12 Months Through MRI. — 92.81; 85.22 Percentage of lesion fill — p=0.011
N/A N=18 High-Purity Type I Collagen Augmentation in Meniscal Repair
Meniscus Tear · Knee Meniscus Injury · Meniscal Repair
Primary: Safety of High-Purity Type I Collagen Augmentation — 0; 0; 0; 0 Participants
Phase 2 N=35 IMPACT: Safety and Feasibility of a Single-stage Procedure for Focal Cartilage Lesions of the Knee.
Foreign-Body Reaction · Inflammation · Effusion (L) Knee
Primary: Safety: Adverse Events — 0 participants
N/A N=31 A Biomechanical Exercise Program for Knee OA
Osteoarthritis, Knee
Primary: Change in Lower Extremity Function — 10.6; 7.6; -6.4 Change in scores on a scale
Phase 2 N=24 Treatment of Tendon Injury Using Allogenic Adipose-derived Mesenchymal Stem Cells (Rotator Cuff Tear)
Rotator Cuff Tear
Primary: Change of Pain During Activity From Baseline to 3 Months After Intervention — -1.4; -1.5; -3.0 units on a scale — p=0.35
Phase 2 N=12 Treatment of Knee Osteoarthritis With Autologous Mesenchymal Stem Cells
Osteoarthritis, Knee · Knee Degenerative Disease · Knee Osteoarthritis
Primary: Feasibility and Safety of the Implementation of MSV in the Treatment of Osteoarthritis of the Knee. — 46.9; 25.1; 24.8; 15.4 units on a scale
N/A N=80 Knee Bracing for People With Patellofemoral Osteoarthritis
Knee Osteoarthritis
Primary: Change in Pain on the VIsual Analog Scale (VAS) — -.068 change in units on a scale from baseline
Phase 3 N=9 Evaluation of the CR Plug for Repair of Defects Created at the Harvest Site From an Autograft in the Knee.
Knee Injury
Primary: MRI to Evaluate Success of Outcome. — 88.6 units on a scale
Phase 3 N=40 The Effect of Micro Fragmented Adipose Tissue (MFAT) on Knee Osteoarthritis
Osteoarthritis, Knee · Knee Pain
Primary: Change in Knee Injury and Osteoarthritis Outcomes Score (KOOS) Score - Pain — 64.4; 62.5; 63.9; 13.2 score on a scale — p=0.594