N/A N=10 Physiological Effects of New Polyphenol-enriched Foods in Humans
Healthy
Primary: Serum Polyphenol Concentrations Over 24h From Food Consumption — 1.7; 12.1; 7.7; 0.01 nmol*h/L — p=0.02
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=16 Diet Induced Intestinal Mucosal Adaptation
Healthy Conditions
Primary: Mucosal Surface Enlargement — 10.2; 9.9 percentage of muscular mucosae — p=<0.05
N/A N=30 Nutritional Biomarkers of Sarcopenia
Sarcopenia
Primary: Resting and Maximum Plasma Leucine Concentration — 659; 755; 721; 95 micromoles per liter
N/A N=8 The Effect of Macronutrients on Satiety and Gut Hormone Responses
Eating Behavior
Primary: The Effect of Proteins on the Secretion of Gut Hormones From Different Parts of the Gastrointestinal Tract — 1310; 1073; 1118; 1188 pg*min/mL
N/A N=16 The Role of Altered Nutrient Partitioning in Food Reward
Overweight and Obesity
Primary: Change in Preference- Liking — 6.5; 4.5 units on a scale
N/A N=124 Newborn Feeding and Infant Phenotype
Breast Feeding
Primary: Change in Total Adipose Tissue Volume — 0.718; 0.901; 0.775 Litres
N/A N=51 Physiological Effects of Nutritional Support in Patients With Parkinson's Disease
Parkinson Disease · Idiopathic Parkinson Disease
Primary: Distribution Volume Ratio — 2.65; 2.70; 2.96; 2.74 Distribution volume ratios — p=0.05
Phase 4 N=300 Nutrition, Physical Performance & Fitness in Indian School Children
Physical Fitness · Nutritional Status
Primary: Change From Baseline in Maximal Aerobic Capacity (VO2max)- 12 Inch Step Test After 4 Months — 36.8; 37.9; 37.0; 38.9 mL/kg/min. — p=0.004
N/A N=105 Effects of Fast Bar on Physiological Fasting
Fasting
Primary: Ketone Area Under the Curve — 1.27; 0.62; 1.17 mg/dL*h
N/A N=36 Nutritional Status and Enteral Absorption Capability After Brain Death
Brain Death
Primary: Primary Outcome Measure is IL-6 Level — 565.5; 264.9 pg/ml
N/A N=54 Food Intake Response to Short-Term Modifications of Metabolism in Humans
Healthy Volunteers
Primary: 24-hour Energy Expenditure (kcal) — 2256; 2166; 2563; 2487 kcal
N/A N=44 Maximizing the Dietary Pattern of Older Adults: the Effects of Protein Intake on Protein Kinetics
Sarcopenia
Primary: Whole Body Protein Turnover — -0.16; -0.17; 0.48 g/kg lean body mass/day
N/A N=113 Effect of Infant Formula on Energy Balance
Development
Primary: Growth, Weight for Length (WLZ) Z Scores — -0.26; -0.12; -0.12; 0.13 Z score — p=<0.05
N/A N=30 Impact of Nutritional Supplementation on Aerobic Performance and Fatigue
Performance · Fatigue
Primary: Perceived Exertion — 6.7; 7.4 units on a scale
N/A N=101 Choline Nutritional Status: Development of a Biomarker Panel
Healthy
Primary: Ratio of Liver Choline Pool Size by Isotope Dilution — 0.02357; 0.02403; 0.02184; 0.00023 isotopic enrichment ratio — p=0.0247
N/A N=164 Framingham State Food Study
Obesity · Diabetes · Cardiovascular Disease
Primary: Total Energy Expenditure, Assessed by Indirect Calorimetry Using Stable Isotopes — 2713; 2504; 2640; 190 kcal/d
N/A N=40 A More Physiological Feeding Process in ICU:the Intermittent Infusion With Semi-solidification of Nutrients
Nutrition, Enteral
Primary: the Ratio of the Enteral Nutrition — 0.98; 0.73 ratio
N/A N=20 Essential Amino Acids and Protein Kinetics During Caloric Deprivation
Muscle Protein Synthesis · Whole-body Protein Balance
Primary: Postprandial, Resting Muscle Protein Synthesis Rates — 0.055; 0.061 percent per hour
N/A N=10 Matrix on Fruit Constituent Bioavailability
Healthy Non-smoker
Primary: CMax in Polyphenol Anthocyanin Concentrations — 8.7; 22.1; 7.6; 11.3 nmol/L
N/A N=51 Nutrition and Aerobic Exercise in Chronic Stroke
Stroke
Primary: The Change in Total Daily Energy Expenditure — -0.52; 32.86 change in kcal/day
N/A N=23 Dietary Nitrate and Physiological Aging
Aging
Primary: Change in Carotid Chemosensitivity Following 4 Weeks of Dietary Nitrate Supplementation and Placebo in Older Adults — -0.13; -0.05; -0.10; -0.11 L/min/%SpO2
Phase 4 N=50 Physiological and Psychological Effects of Testosterone During Severe Energy Deficit and Recovery
Caloric Restriction · Exercise
Primary: Body Composition at the End of Each Study Phase — 78.3; 78.0; 73.3; 75.8 kilograms
N/A N=20 Timing of Caloric Intake, Diet-induced Thermogenesis and Hormonal Pattern
Diet-induced Thermogenesis
Primary: Intra-individual Variation in Morning Diet-induced Thermogenesis (DIT) Evaluated by Calorimetric Exam After the Consumption of a Meal at 8:00 am Compared With Evening…
Phase 1 N=62 Muscle Perfusion and Protein Metabolism in Elderly
Aging
Primary: Mixed Muscle Fractional Synthesis Rate (FSR) — 0.061; 0.070; 0.066; 0.070 Fractional Synthesis Rate (pecent/hour)
N/A N=30 Natural Versus Synthetic Vitamin B Complexes in Human
Healthy · Thiamine and Niacin Deficiency States · Pyridoxine Deficiency
Primary: Serum Thiamine — 50.21; 48.33; 51.21; 50.60 "µg/L"
N/A N=10 Novel Approach to Assess Metabolic Flexibility in a Respiratory Chamber
Diabetes Mellitus, Type 2
Primary: Overnight Respiratory Exchange Ratio — 0.832; 0.887 ratio
Phase 3 N=32 Behavioral Mechanism of Energy Compensation With Exercise
Obesity · Weight Loss · Eating Behavior
Primary: Attentional Bias — 48.85 percentage of time fixated on food cues
N/A N=32 Impaired Regulation of Energy Balance in Elderly People (Balance Study)
Anorexia of Ageing
Primary: Energy Intake Compensation — 1; 1 MJ/day
Phase 3 N=31 Thyroid Hormones Homeostasis and Energy Metabolism Changes During Stimulation of Endogenously Secreted Bile Acids (BAs)
Healthy Volunteers
Primary: Energy Expenditure — 1.37; 1.40; 1.28; 1.27 kcal/min — p=0.0001
N/A N=7 The Impact of the Physiological Response to Sugar on Brain Activity and Behavior
Food Preferences · Appetitive Behavior
Primary: Change in Preference- Subjective Liking Ratings for Each Beverage on a Scale — -12.8; -12.0; -12.6 units on a scale