Clinical Trial Search

Primary: Number of Participants Who Preferred Subconjunctival Anesthetic at the Third Follow-up Visit — 50 participants

Primary: Average Pain Score Over the First 30 Post-operative Minutes Using the CHEOPS Scale — 6.36; 6.57; 6.58 units on a scale

Primary: Discomfort Level and Patient Satisfaction With the Preparation Protocol and Intravitreal Injection — 2.1; 2.09; 1.7; 2.0 units on a scale

Primary: Conjunctiva Anesthesia With Chloroprocaine 3% Eye Gel as Compared With Oxybuprocaine Chlorhydrate 0.4% Eye Drops — 19; 23 participants

Primary: Change in Ln(Bacterial Colony Count) From Pre-antibiotic Administration to Post Study Medication Swabs — -0.14; -0.52 Ln(bacterial colony count)

Primary: Subjective Injection Pain — 7.0; 3.1; 3.0; 1.8 units on a scale

Primary: Number of Participants in Each Treatment Group With a Successful Surface Anesthesia — 153; 152; 14; 19 participants

Primary: The Number of Patients Who Experienced Ocular Anesthesia Following Treatment of AG-920 Compared to Placebo at 5 Minutes — 41; 2 Participants

Primary: The Percentage of Patients Who Experienced Ocular Anesthesia Following Treatment of AG-920 Compared to Placebo at 5 Minutes — 50; 11; 10; 49 Participants

Primary: Pain on Injection — 2.8; 3.6 score on a scale

Primary: Discomfort Associated With the Intravitreal Injection — 3; 2.3; 2.8; 3.1 units on a scale — p=0.28

Primary: Intraocular Pressure (IOP) — 18; 16; 19; 16 mmHg

Primary: The Proportion of Participants in Which an Eye Exam Was Able to be Performed — 30; 30 Participants

Primary: Participants Anesthetic Preference — 32; 16 participant preference selection

Primary: Duration of Anesthesia(Minutes) — 80; 140; 0; 400 Minutes

Primary: Subjective Comfort Scores — 79.25; 70.93; 61.00; 61.94 Units on a Scale

Primary: Pulpal Anesthesia — 25; 14 participants

Primary: Intensity of Perceived Maternal Pain as Measured by the Visual Analogue Scale (VAS) — 9.5; 18.4 units on a scale

Primary: Handgrip Strength — 6.45; 2.98 kg

Primary: Measurement of Pain Associated With Injection, in Millimeters, According to Visual Analog Scale — 38.5; 26.9 mm

Primary: Self-reported Pain After Laser Treatment — 4.5; 5.0 score on a scale — p=0.102

Primary: Number of Study Participants With Positive Conjunctival Culture — 1; 1 Participants — p=0.28

Primary: Time to Resolution of Motor Block — 109; 112 minutes

Primary: Number of Participants Who Completed the Study Dental Procedure After Without Need for Rescue by Injection of Local Anesthetic. — 84.1; 27.3; 27.3 percentage of patients

Primary: Time Taken to Achieve Adequate Akinesia — 41; 41; 9; 9 participants

Primary: Post Operative Pain — 13; 10 Participants

Primary: Visual Analogue Scale(0-100mm) by the Subject. — 51; 40; 22; 9 mm

Primary: Number of Participants Gaining Full Conjunctival Anesthesia of the Ocular Surface — 61; 2 Participants

Primary: Participant Pain Control — 4.5; 5.87; 4.63; 5.00 units on a scale — p=0.16

Primary: Post-operative Pain Level 6 Hours on a Visual Analog Scale — 64.2; 43.1 units on a scale