N/A N=299 Primary Care Intervention to Reduce Prescription Opioid Overdoses
Pain · Drug Overdose · Opioid Use Disorders
Primary: Overdose Risk Behaviors — 1.31; 1.21; 1.45; 1.25 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=204 Safety & Prevention Outcomes Study
Drug Overdose · Opioid-Related Disorders
Primary: Overdose Risk Behavior — -1.54; -0.51 Scores on a scale
N/A N=286 A Patient-Centered Intervention to Improve Opioid Safety
Opioid Safety · Prescription Opioid Misuse · Chronic Pain
Primary: Current Opioid Misuse Measure (COMM) — 11.3; 11.9; 9.4; 9.5 score on a scale — p=<0.05
N/A N=652 EHR-Based Medication Complete Communication Strategy to Promote Safe Opioid Use
Opioid Use, Unspecified
Primary: Safe Medication Dosing (Prescription Understanding) — 0.67; 0.83; 0.79 probability
N/A N=115 Opioid Treatment and Recovery Through a Safe Pain Management Program
Depression · Opioid Use · Chronic Pain
Primary: Odds of Morphine Equivalent Daily Dose (MEDD) of Opioid Prescription >=50 mg — 0.209; 0.417; 0.185; 0.364 odds of prescription high dose — p=0.956
N/A N=286 Guiding Aging Long-Term Opioid Therapy Users Into Safer Use Patterns
Pain · Opioid Use
Primary: Count of Referrals to Non-opioid Care — 3.075; 3.61 Count of referrals — p=0.213
N/A N=190 Opioid Prescribing After Cesarean Delivery
Surgery · Opioid Use
Primary: Unused Opioids — 5; 10 oxycodone 5mg tablets
N/A N=76 Evaluation of a Computerized Opioid Overdose Prevention Program
Computer + Fluency · Computer Only · Treatment as Usual
Primary: Knowledge Gain — 30.6; 30.5; 27.56; 40.7 units on a scale
N/A N=712 Evaluation of an Interactive Opioid Risk Education Program (STOMP) for Parents
Pain, Postoperative · Medication Adherence · Opioid Use
Primary: Opioid-related Risk Knowledge — 287; 289 Participants
N/A N=503 Scenario Tailored Opioid Messaging Program (STOMP) to Improve Risk Understanding in Young Adults
Pain, Postoperative · Medication Adherence · Opioid Use
Primary: Opioid Risk Perception — 31.4; 31.1; 32.8; 30.02 score on a scale — p=.001
N/A N=127 Post-op Crowd Sourcing Health Data Via Text-messaging
Orthopedic Surgery · Opioid Use · Acute Injuries Knee
Primary: Number of Opioid Tablets Taken Within 28 Days — 8.05; 11.55 number of pills taken
Phase 2 N=176 Study to Test the Efficacy of Online Education to Increase Safe Use of Opioid Medication.
Medication Adherence
Primary: Self-efficacy - 8 Item Measure Taps Into Key Concepts Associated With Confidence for Managing Opioid Medications — 28.1081; 27.0563; 29.7143; 28.3224 units on a scale
N/A N=196 Discharge Opioid Education to Decrease Opioid Use After Cesarean
Opioid Use
Primary: Opioid Use — 7.5; 10 hydrocodone tablets
N/A N=555 Application of Economics & Social Psychology to Improve Opioid Prescribing Safety Trial 1: EHR Nudges
Opioid Abuse, Unspecified
Primary: Change in Average Per-clinician Log Total Weekly MME Between Baseline and Intervention for Opioid Naïve and At-Risk Patients (Below 50 MME Daily Dose Rxs) — -0.14; -0.05…
N/A N=5,411 Comparing State Payer Strategies to Prevent Unsafe Opioid Prescribing
Opioid Use · Opioid-Related Disorders
Primary: Subacute Phase - More Than 7 Days of Opioids — 1.9; 12.2 % of participants — p=<.001
N/A N=395 Naloxone Auto-injector as a Universal Precaution for Patients With Opioid Use Disorder
Opiate Antagonist Overdose · Opioid-Related Disorders
Primary: To Measure the Association of Take-home Naloxone With Overdose Reversals Performed by Patients With Opioid Use Disorder Enrolled in an Opioid Treatment Program — 73; 263…
N/A N=111 Opiate Prescribing Guidelines Following Hip Arthroscopy
Hip Injuries
Primary: Numeric Pain Rating Scale (NPRS) Pain Scores — 4.2; 4.0 score on a scale
N/A N=1,588 Evaluation of a Health Plan Initiative to Mitigate Chronic Opioid Therapy Risks
Drug Use Disorders · Drug Abuse · Drug Addiction
Primary: Proportion With Prescription Opioid Use Disorder (Defined by DSM5 Criteria). — 0.215; 0.239 proportion of COT patients
Phase 4 N=129 Toward Zero Prescribed Opioids for Outpatient General Surgery
Opioid Misuse and Addiction · Pain
Primary: Morphine Milligram Equivalents Taken by Participants — 46; 15; 0 morphine milligram equivalents
N/A N=240 Opioid Use After Thyroid and Parathyroid Surgeries
Thyroidectomy · Parathyroidectomy · Opioid Use
Primary: New Opioid Discharge Prescriptions — 128; 28 Participants
Phase 3 N=5,521 Opioid Prescription After Cesarean Trial
Pregnancy Related · Opioid Use · Pain
Primary: Number of Participants With Worst Pain Score of Moderate to Severe on the Brief Pain Inventory — 1497; 1535 Participants
N/A N=49 Consensus-based Algorithms to Address Opioid Misuse Behaviors Among Individuals Prescribed Long-term Opioid Therapy
Opioid Misuse · Chronic Pain
Primary: Feasibility of Algorithms — 7; 13 Participants
N/A N=5,446 Best Practice Alert for Opioid Prescribing
Opioid Use
Primary: Opioids Prescribed at Discharge — 100; 75 miligram morphine equivalents
N/A N=140 Opioid Consumption and Disposal After Shoulder Arthroplasty
Opioid Use
Primary: Difference in Proportion of Participants With > 10 Pills Left Unused. — 49; 47 Participants
Phase 4 N=319 Increasing Naloxone Access for Persons Who Use Opioids
Naloxone
Primary: The Number of Participants That Completed the Training in 6 Months — 55; 56; 10; 9 Participants
N/A N=237 Default Dosing Settings for Opioid Prescriptions to Adolescents and Young Adults After Tonsillectomy
Tonsillectomy
Primary: Number of Doses in the Initial Discharge Opioid Prescription — 22.3; 16.1; 33.7; 30.4 Doses
Phase 4 N=304 Comparing Opioid Prescription Patterns in Total Joint Arthroplasty Patients
Postoperative Pain
Primary: Morphine Milligram Equivalents (MME) of Oxycodone Tablets Taken by Patient — 1089.7; 777.1 Morphine Milligram Equivalents (MME)
Phase 2 N=820 Veterans' Pain Care Organizational Improvement Comparative Effectiveness Study
Chronic Pain
Primary: Pain Response — 58; 54 Participants
Phase 2 N=120 Ambulatory Gynecologic Surgery: Finding the Optimal Opioid Prescription
Surgery
Primary: Number of Oxycodone Tablets Used Day 1 — 1.0; 1.0 Oxycodone Tablets — p=.87
N/A N=53,132 Physician Coaching to Reduce Opioid-related Harms
Substance Abuse · Chronic Pain
Primary: Overall Rate of Opioid Prescribing — 0.012; 0.013 Proportion of patients