N/A N=37 Pleural Manometry for the Characterization of Spontaneous and Tension Pneumothorax
Pneumothorax · Tension Pneumothorax
Primary: Pleural Pressure (Ppl) Prior to Evacuation of Pleural Air — 7.44; -1.79 cmH2O
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=260 Comparison Of Chest Ultrasound Techniques To Identify Clinically Significant Pneumothorax
Pneumothorax
Primary: Pneumothorax (Positive or Negative) — 17; 21 participants
N/A N=109 Prospective Evaluation of 14F Thal Tube vs 28 French Chest Tube for Hemothorax and Use of Maximum Barrier Precautions
Hemothorax · Hemopneumothorax; Traumatic · Empyema
Primary: Number of Participants With Retained Hemothorax Following Initial Chest Tube Placement Requiring Intervention — 51; 48 Number of Participants — p=0.036
N/A N=198 Chest Tube Drainage of Transudative Pleural Effusions Hastens Liberation From Mechanical Ventilation
Liberation From Mechanical Ventilation
Primary: Total Days of Mechanical Ventilatory Support — 6.51; 4.02 days
Phase 3 N=339 Bio-Seal Biopsy Track Plug for Reducing Pneumothorax Rates Post Lung Biopsy Procedure
Pneumothorax
Primary: Incidence Rate of Treatment Success — 126; 94 participants
Phase 4 N=32 Fibrinolysis Compared to Thoracoscopy for Pleural Infection
Pleural Infection · Empyema · Pleural Diseases
Primary: Duration of Hospital Stay After Intervention — 4; 2 days
N/A N=100 Vacuum vs Manual Drainage During Unilateral Thoracentesis
Pleural Effusion · Pleural Diseases · Thoracic Diseases
Primary: Pain Change — 0.53; 1.43 Pre-post NPRS Pain Scale Score
Phase 4 N=5 Fibrinolytic Therapy Versus Medical Thoracoscopy
Pleural Diseases
Primary: Number of Hospital Days for Required to Treat Complicated Parapneumonic Effusions or Pleural Empyema. — 13; 18.5 days
Phase 4 N=121 PleuraSeal Post Market Study (Europe)
Lung Disease · Pulmonary Lobectomy
Primary: Percentage of Subjects Remaining Air Leak Free From Time of Skin Closure to Hospital Discharge. — 41.9; 30.5 Percentage of participants — p=0.257
Phase 3 N=454 Effect of Autologous Blood Patch Injection Versus BioSentry Hydrogel Tract Plug in the Reduction of Pneumothorax Risk Following Lung Biopsy Procedures
Lung Biopsy
Primary: the Rate of Pneumothorax — 42; 60; 184; 168 Participants
N/A N=40 Lung Collapse With Bronchial Blocker
Video-assisted Thoracoscopic Surgery · Lung Isolation Device · One-lung Ventilation
Primary: Time to Obtain Complete Lung Collapse — 47.8; 32.5 minutes
N/A N=20 Comparative Effectiveness of Unilateral vs. Bilateral Pulmonary Collapse in Cardiac De-airing
Brain Ischemia · Reduction of Cerebral Air Emboli
Primary: Quantitative Assessment of Air Embolism to the Brain After Completion of Open Left Heart Surgery — 46; 32 gaseous cerebral microemboli — p=1.00
N/A N=200 Lung Ultrasonography vs Fiberoptic Bronchoscopy for Aiding Lung Collapse in Patient Using Double Lumen Tube
Lung Diseases · Ultrasonography · Fiberoptic Bronchoscopy
Primary: Number of Patients of Lung Collapse in Ultrasonography and Fiberoptic Bronchoscopy — 89; 83 Participants
Phase 3 N=260 Effectiveness Novel Tissue Sealant, Prevention Prolonged Air Leak (PAL) After Lung Resection
Prolonged Air Leak · Lung Resection
Primary: Number of Participants With Prolonged Air Leak (PAL) — 33; 24 Participants — p=0.171
Phase 4 N=27 Intrapleural Fibrinolytic Therapy to Enhance Chemical Pleurodesis Enhance Chemical Pleurodesis
Pleural Effusion
Primary: Chest X-ray Results on Day 3 After Pleurodesis — 5; 6; 5; 8 Participants — p=0.863
N/A N=25 Catheter Placement for Hepatic Hydrothorax
Pleural Effusion
Primary: Feasibility of Using Indwelling Tunneled Pleural Catheters for the Management of Hepatic Hydrothorax — 25 Participants
Phase 3 N=97 Intrapleural DNase and Tissue Plasminogen Activator in Pediatric Empyema (DTPA Trial)
Pleural Empyema
Primary: Time to Hospital Discharge — 9.0; 9.1 days
N/A N=35 Effects of Pneumatic Vitreolysis on Macular Hole
Vitreomacular Traction (VMT) · Full-thickness Macular Holes (MH)
Primary: Proportion of Eyes With Macular Hole Closure of Inner Retinal Layers Without Rescue Vitrectomy — 10 Eyes
N/A N=139 Non-Contrast 4DCT to Detect Pulmonary Thromboembolic Events
Pulmonary Thromboembolisms · Pulmonary Embolism
Primary: Correlation of 4DCT Identified Perfusion With SPECT/CT Identified Perfusion — 0.45 Spearman correlation
N/A N=100 Efficacy and Safety of Activase (Ateplase) vs Placebo in Complicated Pleural Effusions (CPE)/Empyemas
Pleural Effusion Associated With Pulmonary Infection · Bacterial Pleural Effusion Other Than Tuberculosis
Primary: No Surgical Intervention — 66; 6 participants — p=<0.001
N/A N=10 Treatment of Complicated Parapneumonic Effusion With Fibrinolytic Therapy Versus VATs Decortication
Parapneumonic Effusion · Empyema, Pleural · Coagulopathy
Primary: Hospital Length of Stay — 12.4; 8.4 days
N/A N=78 Nitrous Oxide for Identifying the Intersegmental Plane in Segmentectomy: A Randomized Controlled Trial
Pulmonary Nodule, Solitary · Pulmonary Nodule, Multiple · Lung Cancer
Primary: The Intersegmental Border Appearance Time During the Surgery — 320.20; 552.39; 968.33 seconds
N/A N=112 Progel® Pleural Air Leak Sealant (PALS) in Video and Robotic Assisted Thoracoscopic Surgery
Pulmonary Disease
Primary: Rate of Device and/or Procedure-related Adverse Events — 42.5 percentage of participants
N/A N=52 Application of Carbon Dioxide for Identifying the Intersegmental Plane in Thoracoscopic Segmentectomy
Lung Cancer · Pulmonary Nodule, Solitary · Segmentectomy
Primary: The Intersegmental Border Appearance Time During the Surgery. — 748.74; 157.11 seconds
N/A N=117 Intraoperative Neuromuscular Blockade and Postoperative Atelectasis
Thoracic Surgery · One-lung Ventilation
Primary: Atelectasis Area on Chest CT — 1.32; 1.41 percentage of atelectasis volume
N/A N=86 ENB-GS-TBLB for the Diagnosis of PPLs
Lung Cancer
Primary: The Difference of Diagnostic Value of ENB-GS-TBLB as Compared to GS-TBLB — 34; 25; 5; 16 participants — p=0.019
Phase 3 N=72 Intrapleural Bevacizumab and Cisplatin Therapy for Malignant Pleural Effusion Caused by Non-small Cell Lung Cancer
Malignant Pleural Effusion
Primary: Number of Participants With "Complete Response" and "Partial Response" — 17; 2; 13; 15 participants
N/A N=120 Study of PneumRx Endobronchial Coil System in Treatment of Subjects With Severe Emphysema
Emphysema
Primary: Percent Change in FEV1 at 6 Months — 12.745; -2.604 percent change from baseline
N/A N=251 Efficacy of Post-operative Antibiotic Prophylaxis for Thoracic Surgery Requiring Tube Thoracostomy
Antibiotic Prophylaxis
Primary: Number of Participants Who Experienced At Least One Postoperative Infectious Complication — 13; 8 Participants — p=.26
N/A N=49 Physiology of Lung Collapse Under One-Lung Ventilation: Underlying Mechanisms
Lung Collapse · One-Lung Ventilation · Thoracic Surgery
Primary: Quantification of Gas Volume Coming From Ambient Air Towards the Alveoli Space of the Non-ventilated Lung During OLV With the Use of DLT and BB. — 504; 630 milliliters…