N/A N=150 Preoxygenation With Positive Inspiratory Pressure During Induction of Anesthesia
Anesthesia
Primary: Time for Preoxygenationfrom Face Mask Positioning to FEO2=90% — 190; 153; 140 seconds
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=164 Positive Pressure Treatment of Obstructive Sleep Apnea
Obstructive Sleep Apnea
Primary: Apnea-Hypopnea Index — 6.09; 3.54; 3.24; 1.26 events/hour — p=0.3
N/A N=20 GO2 PEEP Study: Bidirectional Oxygenation Valve in Postoperative Atelectasis
Postoperative Atelectasis
Primary: Partial Pressure of Oxygen (PaO2 Level) — 95.4; 83.5; 92.1; 85.4 mmHg
N/A N=22 Non-invasive Ventilation System in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
Pulmonary Disease, Chronic Obstructive · Airflow Obstruction, Chronic · Chronic Obstructive Airway Disease
Primary: Device Tidal Volume — 180 mL
N/A N=37 Preoxygenation With Nasal Cannula and Noninvasive Positive Pressure Ventilation
Hypoxia
Primary: End-tidal Oxygen — 78.1; 78.6 End tidal oxygen saturation percentage
N/A N=28 Study of Standard Noninvasive Positive Pressure Ventilation (NIPPV) and Low Expiratory Pressure NIPPV in ALS Patients
Amyotrophic Lateral Sclerosis
Primary: Hours of NIPPV Usage — 49.94; 45.75 hours
N/A N=72 Positive Pressure at Induction of Anesthesia in Children
Continuous Positive Airway Pressure · Hypoxia · General Anesthesia
Primary: Time Between Onset of Apnea and the Drop in 95% Oxyhemoglobin Saturation Levels — 227.65; 133.68 seconds — p=<0.0001
N/A N=6 Assessment of End Expiratory Lung Volumes in Healthy Subjects Using High Flow Oxygen (Vapotherm®)
Healthy Adult Volunteers
Primary: Change in End-expiratory Lung Volume — -144; 103 mL
N/A N=30 In-home Evaluation of a Noninvasive Open Ventilation System in Patients With Severe Respiratory Insufficiency
Pulmonary Disease, Chronic Obstructive · Airflow Obstruction, Chronic · Chronic Obstructive Airway Disease
Primary: Activity Endurance Time — 7.24; 13.38 minutes — p=<0.05
N/A N=29 Electric Blower Based Ventilator Used During Procedural Sedation
Apnea During Procedural Sedation
Primary: Percentage of Time the Patient Will Experience Apnea — 11 % time in apnea of total study duration
N/A N=20 High Intensity Non-Invasive Positive Pressure Ventilation (HINPPV)
Chronic Obstructive Pulmonary Disease (COPD)
Primary: Daytime Partial Pressure of Carbon Dioxide in Arterial Blood (PaCO2) — 53; 50 mmHg — p=0.01
Phase 2 N=18 PEEP as Rescue Therapy for Asthmatics With Elevated BMI
Asthma
Primary: Central and Peripheral Elastance — 391; 461; 587; 334 cmH2O/L
N/A N=34 Study of Nasal Ventilation In Preterm Infants To Decrease Time on The Respirator
Bronchopulmonary Dysplasia
Primary: Number of Days Being Intubated — 12.4; 6.2 days
N/A N=25 Vitabreath Pilot in Chronic Obstructive Pulmonary Disease (COPD) Patients
COPD · Dyspnea
Primary: Average Distance During Modified 6 Minute Walk Test — 128.0; 129.9; 137.5; 121.3 meters — p=0.02
N/A N=16 Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome · ARDS
Primary: Mechanical Power — 1.87; -2.50 J/min — p=.002
N/A N=25 Servo-Ventilation In-lab PSG Evaluation
Sleep Apnea Syndromes
Primary: Average Apnea Hypopnea Index Among Different Polysomnography Devices. — 18.4; 25.4; 24.1; 19.2 events per hour
N/A N=40 Prophylactic nCPAP Following Bowel Surgery (Bio-REB File 11-27)
Postoperative Pulmonary Atelectasis · Surgery
Primary: Alveolar - Arterial Gradient — 70.6; 134 torr
N/A N=2 Bidirectional Oxygenation Valve in the Management of Pulmonary Complications of COVID-19
COVID-19
Primary: Oxygen Saturation by Pulse Oximetry — 92; 93.5; 94; 94 percentage of oxygen saturation
N/A N=15 Effects of the Breathe Technologies Ventilation System in Subjects With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease
Primary: Exercise Duration for Constant Work Rate Exercise Tests Under 4 Test Conditions — 6.3; 17.5; 11.4; 5.6 minutes — p=<0.05
N/A N=194 Effect of Positive Airway Pressure on Reducing Airway Reactivity in Patients With Asthma (CPAP)
Asthma
Primary: Methacholine Reactivity — 2.13; 1.48; 1.44; 1.60 mg/mL — p=0.51
N/A N=34 Positive Airway Pressure Program
Sleep Apnea, Obstructive
Primary: Participant Providing Feedback — 26 Participants
Phase 2 N=30 High Flow Oxygen and Bilevel Airway Pressure for Persistent Dyspnea in Patients With Advanced Cancer
Advanced Cancers
Primary: Number of Participants Completing Study Intervention — 7; 10; 3; 5 Participants
N/A N=60 Evaluation Of The Total Face Mask For Emergency Application In Acute Respiratory Failure
Acute Respiratory Insufficiency
Primary: Mask Comfort (as Determined by the Visual Analog Scores 1 Being Least, 10 Being Most) — 3.2; 3.3 units on a scale
N/A N=21 Adjustment of Mask Pressure, for Bilevel Positive Airways Pressure Therapy, by Automated Algorithm
Respiratory Insufficiency · Sleep Disordered Breathing
Primary: Index of Apneoas Plus Hypopnoeas Per Hour of Sleep (AHI) — 1.3; 1.7 Events per hour of sleep
N/A N=39 A Comparison of Different Ventilation Strategies in Infants Using the PLMA™
Ventilation
Primary: Mean Values of End-tidal Carbon Dioxide and Tidal Volume Compared Between the Spontaneous Ventilation and Pressure Support Ventilation Groups. — 4.5; 7; 51.8; 49 cc/kg
Phase 2 N=54 Effectiveness of Continuous Negative External Pressure in Preventing Upper Airway Impairment During Routine Colonoscopy
Airway Obstruction · Apnea · Hypopnea
Primary: RI Events in the cNEP Group Compared to the no cNEP Group, Where RI is Defined as Either: i Oxygen Saturation < 90% or ii. Apneas/Hypopneas of > 15 Sec Duration i…
N/A N=50 EPO2-A: Evaluation of Pre-Oxygenation in Morbid Obesity: Effect of Position and Positive Pressure Ventilation
Obesity, Morbid
Primary: Non Hypoxic Apnea Time — 216.7; 258.2 seconds — p=0.005
N/A N=70 Ventilation Using a Bag Valve Mask With Integrated Internal Handle
Apnea
Primary: Mean Received Tidal Volume — 681; 591 milliliters
N/A N=751 Protocolized Post-Extubation Respiratory Support Study
Mechanical Ventilation Complication · Acute Respiratory Failure · Intubation Complication
Primary: Reintubation — 57; 52 Participants
N/A N=21 Positive Airway Pressure for the Treatment of Asthma
Asthma · Sleep Apnea
Primary: Asthma Control Test — 19.3; 19.8; 19.1; 19.6 units on a scale — p=0.8