N/A N=47 Post-Operative Cognitive Dysfunction in Normal Aging Patients Undergoing Elective Orthopedic Surgery
Post Operative Cognitive Dysfunction
Primary: Presence of Post Operative Cognitive Dysfunction (POCD) — 15 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=45 Prevention of Early Postoperative Decline
Delirium · Postoperative Cognitive Dysfunction
Primary: Feasibility of Providing a Neurocognitive Training Program to Elderly Cardiac Surgical Patients - Enrollment — 45 Participants
N/A N=116 Perioperative Mental Health in Orthopedic Surgery
Orthopedic Surgery · Older Adults · Depression
Primary: PHQ-ADS (Patient Health Questionnaire Anxiety and Depression Scale) — 16.84; 19.35; 11.26; 13.09 Points
N/A N=29 Behavioral Activation and Medication Optimization for Perioperative Mental Health Feasibility Study
Older Adults · Anxiety · Depression
Primary: Reach of the Study as Measured by the Number of Participants Who Agree to Participate in the Study Out of the Total Eligible Participants — 23 Participants
N/A N=575 Persistent Pain After CS Delivery
Persistent Pain After Delivery
Primary: Persistent Pain-PERCEIVED STRESS Scores Stratified by the Rate of Recovery — 11.4; 12.9; 15.4 units on a scale — p=<0.01
N/A N=203 Postoperative Cognitive Dysfunction as Geriatric Syndrome
Cognitive Dysfunction
Primary: Postoperative Cognitive Dysfunction - Results of MMSE Before Operation — 79; 43; 37; 5 Participants — p=<0.0001
Phase 2 N=241 Psychological Influences on Postoperative Recovery
Care, Postoperative · Pain, Postoperative · Surgical Procedures, Operative
Primary: Modified Yale Preoperative Anxiety Scale — 41.59; 37.44; 46.17; 33.65 Score on mYPAS scale — p=.02
N/A N=30 Assessment of Cognitive Function After Surgery in Two Types of Anesthesia in Patients Operated for Breast Cancer
Patients With Breast Cancer and Breast Surgery Requiring
Primary: Presence of Cognitive Impairment — 29.5; 29 score on a scale
N/A N=135 Effect of CPAP on Postoperative Delirium
Sleep Apnea, Obstructive · Delirium
Primary: Presence of Postoperative Delirium — 4.8; 5.1; 7.8; 8.1 units on a scale
N/A N=36 Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition
Postpartum Depression
Primary: Blood-oxygen-level-dependent (BOLD) Response During Functional Magnetic Resonance Imaging (fMRI) z Statistic — 2.3; 2.0; 2.1; 1.7 z score — p=.27
N/A N=91 Postoperative Delirium: Brain Vulnerability and Recovery
Delirium · Postoperative Complications
Primary: EEG During Delirium and After Recovery and in Patient Controls.
N/A N=250 Assessing the Incidence of Postoperative Delirium Following Aortic Valve Replacement
Postoperative Delirium · Aortic Valve Stenosis
Primary: Number of Participants With Postoperative Delirium — 13; 41; 45 Participants — p=<0.0001
Phase 2 N=144 Olanzapine for Nausea After Surgery
Postoperative Nausea and Vomiting
Primary: Number of Participants With Nausea and/or Vomiting — 10; 26 Participants — p=0.003
N/A N=204 Impact of Opioid Free Anesthesia on Outcome After DIEPflap Surgery
Major and Minor Surgical Complications
Primary: Number of Patients With One or More Complications — 10; 85 Participants — p=<0.001
Phase 4 N=135 Preventing Post-Operative Delirium in Patients Undergoing a Pneumonectomy, Esophagectomy or Thoracotomy
Delirium · Cognitive Impairment · Post-traumatic Stress Disorder
Primary: Efficacy of Low-dose Haloperidol in Reducing Delirium Incidence — 15; 19 Participants
N/A N=200 Post-Operative Delirium in Elderly Surgical Patients
Hip Fractures · Delirium
Primary: Number of Participants With the Presence of Delirium as Assessed by the Confusion Assessment Method — 39; 34 Participants
Phase 4 N=67 Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries
Pain · Postpartum Depression
Primary: Perineal Pain in Postpartum Patients 1 Week After Obstetric Anal Sphincter Injuries. — 3.5; 2.7; 2.4 score on a scale
Phase 3 N=32 Ketamine for Postoperative Avoidance of Depressive Symptoms: The K-PASS Feasibility Trial
Postoperative Depression
Primary: Fraction of Approached Patients Who Enroll and Are Randomized — 1; 31 Participants
N/A N=132 Postoperative Environment on Pain Following Pelvic Reconstructive Surgery
Postoperative Pain
Primary: Visual Analog Scale (VAS) Score for Pain — 28.0; 24.5 millimeter (mm) — p=0.57
Phase 3 N=72 Postoperative Consequences of Intraoperative NOL Titration
Anesthesia; Adverse Effect
Primary: Pain Scores at 10-minute Intervals for the Initial Hour of Recovery — 0; 0; 1.0; 5.0 score on a scale — p=0.895
Phase 4 N=60 Comparison of Postoperative Delirium in Patients Anaesthetised With Isoflurane and Desflurane During Spinal Surgery
Postoperative Delirium
Primary: Comparison of Postoperative Delirium(POD) With Isoflurane and Desflurane on Adults Undergoing Spine Surgery — 3; 4; 27; 26 Participants
N/A N=312 PRogram In Support of Moms: An Innovative Stepped-Care Approach for Obstetrics and Gynecology Clinics
Depression
Primary: Change in Edinburgh Postnatal Depression Scale Score (EPDS) — -4.3; -4.2 score on a scale
N/A N=205 Depression Attention for Women Now (The DAWN Study)
Depressive Disorder
Primary: Depression Treatment Outcome — 0.96; 1.33 units on a scale
N/A N=42 Mommy-Baby Treatment for Perinatal Depression
Depressive Disorder, Major · Postpartum Depression
Primary: Change in Edinburgh Depression Scale From Baseline — 17.81; 17.9; 12.04; 11.41 units on a scale
N/A N=54 Postoperative Virtual Clinical Encounters
Pelvic Organ Prolapse
Primary: Patient Satisfaction Via the Patient Satisfaction Questionnaire -18 — 80.7; 81.2 score on a scale
Phase 4 N=120 Post Operative Sore Throat and Dexamethasone
Sore Throat · Pain
Primary: Subjects Assessment of Sore Throat Pain at 24 Hours — 4; 4; 5 units on a scale (1 to 5) — p=<0.001
N/A N=240 Opioid Use After Thyroid and Parathyroid Surgeries
Thyroidectomy · Parathyroidectomy · Opioid Use
Primary: New Opioid Discharge Prescriptions — 128; 28 Participants
N/A N=248 Postoperative Management for Degenerative Spinal Conditions
Spinal Degenerative Disorder
Primary: Oswestry Disability Index (ODI) — 43.6; 45.46; 31.31; 31.19 units on a scale
N/A N=179 Persistent Postoperative Pain and Joint Stiffness After Total Knee Arthroplasty Performed for Osteoarthritis
Pain · Joint Stiffness
Primary: Presence of Persistent Postoperative Pain Using the Numeric Rating Scale (NRS) — 10 Participants
N/A N=69 High Pain Intervention in Cesarean Sections
Other Chronic Postoperative Pain
Primary: Severity of Acute Pain — 46; 31 mm — p=0.05