N/A N=60 Conscious Sedation for Epilepsy Surgery
Epilepsy
Primary: Patients Satisfaction — 6.33; 6.45 score on a scale
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Early Phase 1 N=300 Sedation Regimens in GI Endoscopy
Anesthesia · Endoscopy · Colonoscopy
Primary: Pain Felt During the Procedure — 0.29; 0.30 score on a scale
N/A N=86 Sedation and Pain (The Effect of IV Sedation on Pain Perception)
Pain
Primary: Pain Rating Change — -0.253; 0.762; -0.346 units on a scale
N/A N=36 Sedatives' Effects on Neurological Function in Patients With Eloquent Area Glioma
Glioma
Primary: Task Completing Time Change Between Sedation and Baseline Measured by 9-hole Peg Test — 27.8; 19.1; 54.3; 21.4 seconds — p=<0.01
Phase 4 N=50 Alternative Sedation During Bronchoscopy
Sedation
Primary: Decreased Minute Ventilation — 0.736; 0.764 percentage of baseline — p=<0.0001
N/A N=11 Sedation in Patients at Risk for Upper Airway Collapse
Obstructive Sleep Apnea
Primary: Respiratory Disturbance Index — 57.52; 21.32 events per hour
N/A N=10 Effects of Two Different Sedation Regimes on Auditory Evoked Potentials and Electroencephalogram (EEG)
Conscious Sedation · Deep Sedation · Critical Care
Primary: Amplitudes (in Micro Volts) of Acoustic Event Related Potentials (Time-locked Amplitudes in the Electroencephalogram 100 Milliseconds After the Acoustic Stimulus…
N/A N=110 Sedline EEG Guided Depth of Anesthesia
Anesthesia · Surgery
Primary: Total Average Anesthetic — 1.1890; 1.2906 percentage of sevoflurane
Phase 4 N=105 Sedation Methods During Cataract Surgery
Phacoemulsification · Cataract
Primary: Eye Mobility During Surgery (See Link to Study Protocol for Scale) — 1.39; 1.41; 1.31 units on a scale
Phase 2 N=15 Testing the Feasibility of Patient Controlled Sedation for Ventilated ICU Patients
Acute Respiratory Failure · Anxiety
Primary: Aggregate Sedative Exposure During PCS Use (up to 5 Days). — 4; 3.5 units on a scale
Phase 3 N=50 Sedation Using Intranasal Dexmedetomidine in Upper Gastrointestinal Endoscopy
Gastrointestinal Disease
Primary: Consumption of Rescue Patient Controlled Propofol — 42.4; 28.6 mg
Phase 4 N=107 Moderate Versus Deep Procedural Sedation With Propofol in the Emergency Department
Pain
Primary: Patients With Clinical Signs of Respiratory Depression or Sub Clinical Respiratory Depressions Measured by Capnography and Pulse Oximetry. — 22; 21 Participants
Phase 4 N=40 Sedation Effect of Dexmedetomidine Versus Remifentanil to Fibreoptic Intubation
Intubation; Difficult
Primary: Endoscopy Scores — 3; 2 units on a scale
N/A N=30 Assessment of Cognitive Function After Surgery in Two Types of Anesthesia in Patients Operated for Breast Cancer
Patients With Breast Cancer and Breast Surgery Requiring
Primary: Presence of Cognitive Impairment — 29.5; 29 score on a scale
N/A N=108 Comparison of Depth of Sedation Performance Between SedLine and Comparator Device During General Anesthesia
Anesthesia
Primary: Correlation of Sedation Indices Performance Across Anesthesia Range — 0.8314 Pearson r
Phase 3 N=60 A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients
Anxiety, Dental · Dental Decay
Primary: Incidence of Adverse Sedation-Related Events in Musculoskeletal System During Sedation — 2.8; 3; 2.5500 score on a scale — p=0.016
N/A N=150 Patient-controlled Sedation With Propofol Versus Combined Sedation During Bronchoscopy
Sedation, Bronchoscopy
Primary: Discharge Assessment Using PADSS After 2 Hours Number of Patients Reaching PADSS Score 10 After 2 Hours — 19; 30; 45 Participants
N/A N=300 Combining Objective and Subjective Sedation Assessment Tools
Critical Illness
Primary: Mean Sedative Use — 13.35; 15.54 ml/hour
Phase 2 N=8 Ultrasonic Deep Brain Stimulation During Anesthetic Sedation
Mental Function
Primary: Blood Oxygen Level Dependent (BOLD) Response to Visual Stimuli — 0.56; 0.51 percentage of BOLD signal — p=0.62
Phase 4 N=798 Ancillary Effects of Dexmedetomidine Sedation After Cardiac Surgery
Heart Disease
Primary: Number of Patients With Atrial Arrhythmia — 121; 134 Participants — p=0.34
N/A N=16 Closed Loop Acoustic Stimulation During Sedation With Dexmedetomidine
Sleep · Sedation Complication
Primary: Difference in EEG Slow Wave Activity From Sham to In-phase Stimulation — 1.592; 1.694 Log(μV squared)
N/A N=65 The Effect of Sedation on Eye Movements
Saccadic Eye Movements
Primary: Dynamic Eye Movement Measures — -25; -115; -90; 10 (degrees/second)
N/A N=10 Phamacological Reversal of Airway Instability During Sedation
Upper Airway Obstruction
Primary: AHI - Apnea Hypopnea Index — 14.5; 27.9; 11.3; 12.1 events per hour
Phase 4 N=144 A Comparison of Dexmedetomidine Versus Propofol for Use in Intravenous Sedation
Anesthesia
Primary: Respiratory Events Requiring Intervention — 17; 2 Participants
Phase 4 N=29 Neuroimaging of Anesthetic Modulation of Human Consciousness
Healthy
Primary: Change From Baseline in Blood Oxygen Level Dependent (BOLD) Response to Sensory Stimuli During Sedation — -0.349 percentage of BOLD signal change — p=<0.0001
N/A N=121 Emergence Agitation Between Dexmedetomidine and Sevoflurane Anesthesia
Emergence Delirium
Primary: Emergence Agitation — 3.9; 2.5 Score on a scale — p=0.001
N/A N=1,771 The Emergency Department Sedation Pilot Trial
Mechanical Ventilation · Respiratory Failure
Primary: Participant Recruitment — 196; 219 Participants
Phase 4 N=103 The Effect of Different Sedation Regimes on Cognitive Function in Lower Gastrointestinal System Endoscopy
Gastrointestinal Dysfunction · Alteration of Cognitive Function
Primary: Change in Cognitive Function — 47.5; 40.4; 44.7; 37.8 units on a scale — p=0.001
Phase 4 N=126 Propofol Versus Alfentanil Versus Nitrous Oxide for Moderate Procedural Sedation
Sedation
Primary: Number of Participants With Sub-clinical Respiratory Depression and Clinical Events Associated With Respiratory Depression During the Sedation Procedure — 11; 12…
Phase 4 N=135 Propofol vs. Midazolam-based Balanced Propofol for Nonanesthesiologist Moderate Sedation in Colonoscopy
Procedural Sedation
Primary: Level of Sedation Throughout the Entire Procedure — 22; 9; 10; 1 participants