N/A N=452 Chronic Sleep Deprivation Among the Poor: A Lab-in-the-field Approach
Blood Pressure · Depression
Primary: Sleep Per 24 Hours — 5.61; 5.81; 5.99; 6.23 Hours of sleep/24 hours
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=45 Impact of Sleep Restriction on Performance in Adults
Sleep · Obesity · Sleep Restriction
Primary: Endpoint Fat Volume — 24.0; 24.2 Liter
N/A N=10 Combined and Isolated Effects of Sleep Deprivation and Alcohol Intake on Exercise Performance in Humans.
Alcohol Intake · Sleep Deprivation
Primary: Aerobic Performance — 172; 173; 175; 176 bpm
Phase 2 N=68 Repeated Partial Sleep Deprivation to Augment SSRI Response in Depression
Depression
Primary: Hamilton Rating Scale for Depression-17 Item Minus Sleep Items — 6.1; 8.1; 6.3 units on a scale — p=.202
Phase 2 N=49 The Role of Dopamine Metabolism in the Antidepressant Effects of Sleep Deprivation and Sertraline in Depressed Patients
Major Depressive Disorder · Bipolar Disorder
Primary: Total Score on the Hamilton Rating Score for Depression (HRSD) - 21 Item Version — 19; 18.5; 10.2; 14.4 Total score on a scale — p=<0.05
N/A N=92 Sleep IntervEntion as Symptom Treatment for ADHD
ADHD · Sleep · Adolescents
Primary: Sleep Architecture Objective TST [Total Sleep Time] Pre-test to Post-test — 8.11; 7.94; 8.03; 8.07 hours — p=.17
Phase 2 N=20 Effect of Background Noise on Sleep Quality
Sleep Onset Insomnia
Primary: Sleep Onset Latency (Mins) — 13; 19 minutes — p=0.011
N/A N=20 Sleep Loss and Mechanisms of Impaired Glucose Metabolism
Primary Insomnia
Primary: Change in Glucose Tolerance (Kg) in Response to Insulin-modified Intravenous Glucose Tolerance Test — .33; -0.10 %/min, slope of natural log glucose
N/A N=8 Wake Therapy in the Treatment of Depression
Major Depressive Disorder · Bipolar Disorder
Primary: Structured Interview for the Hamilton Depression Scale With Atypical Depression Supplement(SIGH-ADS) — 16.6 score on a scale
N/A N=20 Poor Sleep and Inflammation in HIV-Infected Adults
HIV-1-infection · Sleep Deprivation · Inflammation
Primary: Soluble CD14 — 1290; 1196 ng/mL
N/A N=1,189 Fire Fighter Fatigue Management Program: Operation Healthy Sleep
Shift-Work Sleep Disorder · Insomnia · Restless Leg Syndrome
Primary: Firefighters' Health, as Determined by Number of 'Sick' Days Over 12 Months — 3.1; 3.2; 1.4; 2.6 days/firefighter — p=0.66
N/A N=1,385 Sleep to Prevent Evolving Affecting Disorders
Insomnia, Primary · Depression
Primary: Severity of Depression as Measured by the Quick Inventory of Depressive Symptomatology (QIDS) Pre-Treatment — 10.8; 10.8 score on a scale
N/A N=16 Sleep Length and Circadian Regulation in Humans
Sleep Disorders
Primary: Dim Light Melatonin Onset (Hours) — 1.93; 0.80 hours
N/A N=108 Association Between Food/Nutrient Intake and Sleep Quality in Middle Aged and Older Population
Sleep
Primary: Sleep Quality Assessment 1 (GSS) — 3.4; 8.1; 5.2 score on a scale
N/A N=9 Evaluation of SmartSleep Technology for Improving the Efficiency and Restorative Quality of Sleep in Healthy Adults
Sleep
Primary: Psychomotor Vigilance Test-Brief (PVT-B) — 3.59; 4.61; 5.55; 3.95 PVT lapses — p=0.36
N/A N=29 Olfactory Contributions to Sleep-dependent Food Craving
Sleep Deprivation
Primary: Functional Magnetic Resonance Imaging (fMRI)-Based Decoding Accuracy of Food vs Non-food Odors in Piriform Cortex — 54.38; 49.65 Percentage correctly classified — p=0.001
N/A N=100 Mechanisms of Sleep Disruption Hyperalgesia
Sleep Deprivation · Pain
Primary: Spinal Sensitization as Assessed by Area of Secondary Hyperalgesia (2HA) After Two Nights of Uninterrupted Sleep and Two Nights of 8 Forced Awakenings — 1276.25…
N/A N=39 Sleep Promotion to Improve Diabetes Management in Adolescents With T1D
Diabetes Mellitus, Type 1
Primary: Sleep Quality: Baseline — 4.3; 4.5 score on a scale
N/A N=36 Modulation of CSF Amyloid-beta Concentrations Via Behavioral Sleep Deprivation and Pharmacological Sleep Induction
Amyloid-beta
Primary: Percent Increase From Mean Baseline (07:00 to 19:00) of Cerebrospinal Fluid (CSF) Amyloid Beta During Sleep Induction and Sleep Deprivation Between 01:00 and 11:00 From…
N/A N=31 Metabolic Effects of Sleep Extension in People With Obesity
Insulin Resistance · Obesity
Primary: Insulin Sensitivity — -3.8; 0.9 µmol/kgFFM/min
N/A N=45 A High Density EEG Comparison of Sleep Patterns in Insomnia
Primary Insomnia
Primary: EEG Power During Sleep — 1.40; 1.17 μV^2/Hz — p=0.2791
N/A N=137 Sleep Specialty Consultation: Improving Management of Sleep Disorders
Sleep Disorders
Primary: Provider Adherence to Sleep Specialist Recommendations — 4; 0; 8; 4 participants
N/A N=23 Long Sleep Duration and Vascular Function
Sleep
Primary: Change From Wake in Central Aortic Pulse Pressure After 11 Hours in Bed — -1.5; 0.5 mm Hg — p=0.36
N/A N=28 The Psychoneuroimmunology of Insomnia
Primary Insomnia
Primary: Positive Antibody Response — 7; 7 participants
N/A N=6 A Sleep Intervention (SLEEP-Extend) for Young Adults At-Risk for Type 2 Diabetes
Diabetes Mellitus, Type 2
Primary: Number of Enrollments in the Study Over One Year — 4; 2 Participants
N/A N=142 Delayed Sleep Timing in Teens Study
Delayed Sleep Phase
Primary: Weekday Sleep Duration - Actigraphy — 6.309; 5.866; 5.880; 5.845 Number of hours — p=0.018
N/A N=89 Impact of Hyperarousal on Simple and Complex Cognitive Task Performance Among Insomnia Sufferers
Insomnia · Primary Insomnia · Chronic Insomnia
Primary: Number of Incorrect Trials During the Computer-administered Attention-Switching Task Test.Attention-Switching Task Latency Error Rate — 5.11; 3.1 trials
N/A N=12 Influence of Nocturnal Light Exposure on the Impairment of Glucose Tolerance Induced by Chronic Sleep Restriction
Glucose Intolerance · Sleep Deprivation · Sleep
Primary: Impairment of Insulin Sensitivity — -0.80; 0.55 (mU/L)^-1 min^-1
N/A N=39 Self-Management in Young Adults With Type 1 Diabetes
Type 1 Diabetes
Primary: Non-dominant Wrist-worn Actigraph to be Worn 24/7 (Spectrum Plus) — 18; -25.8 min per night — p=0.0227
N/A N=18 Sleep Duration in Women With Previous Gestational Diabetes
Gestational Diabetes
Primary: Changes in Fasting Glucose — 10.4; 1.6 mg/dL