N/A N=219 Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study
Respiratory Failure · Mechanical Ventilation · Acute Lung Injury
Primary: To Further Characterize ED Mechanical Ventilation — 500 mL
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=1,705 ED Lung Protective Ventilation to Reduce Complications
Mechanical Ventilation · Ventilator-associated Conditions · ARDS
Primary: Number of Patients That Experience Pulmonary Complications After Admission From the Emergency Department — 171; 38 participants
N/A N=248 Real-time Effort Driven VENTilator Management
Ventilation Therapy; Complications · Diaphragm Disease · Pediatric Respiratory Diseases
Primary: Median Duration of Weaning — 0.09; 1.04; 2.03; 2.10 days — p=.045
N/A N=65 Ventilator-induced Lung Injury Vortex in Patients With SARS-CoV-2
ARDS · Mechanical Ventilation Complication · Ventilator-Induced Lung Injury
Primary: Number of Participants Who Survived and Died — 1; 31; 14; 19 Participants
N/A N=29 Effect of Angulus on Patient-elevation Compliance
Ventilator Adverse Event · Ventilator Associated Pneumonia · Hospital Acquired Condition
Primary: Compliance to Head of Bed Elevation to 30 Degree or More. — 37.3; 32.4 percentage of time
N/A N=32 Effort of Breathing Guided Ventilator Protocol
Ventilators, Mechanical · Work of Breathing
Primary: Percentage of Protocol Recommendations Which Are Accepted by the Clinical Provider — 76 percentage adherant
N/A N=20 Engineering Evaluation of the Helix Ventilator
Respiratory Disease · Pulmonary Disease · Pediatric ALL
Primary: Proximal Pressure From Trilogy Evo Ventilator and Current Device — 8.3; 8.2 cm H2O
N/A N=566 Mode Of Ventilation During Critical IllnEss Pilot Trial
Respiratory Failure
Primary: Ventilator-free Days (VFDs) to Day 28 After Enrollment — 23; 22; 24 Ventilator-free days to day 28
N/A N=26 Volume Guarantee Ventilation in Preterm Infants With Frequent Episodes of Hypoxemia
Episodic Hypoxemia in Mechanically Ventilated Preterm Infants
Primary: Percentage of Time Spent With Arterial Oxygen Saturation < 75% — 5; 4.4 % of time — p=0.44
N/A N=272 Evaluation of the CleanSweep™ Closed Suction System on Length of Mechanical Ventilation and Ventilator-Associated Events
Mechanical Ventilation Complication
Primary: Length of Time on a Mechanical Ventilator — 70.6; 72.2 hours
N/A N=513 Oral Suction Intervention to Reduce Aspiration and Ventilator Events: NO-ASPIRATE
Respiratory Failure
Primary: Microaspiration as Measured by Tracheal Amylase — 13,086; 15,298 U/L — p=0.432
Phase 1 N=30 Extubation Advisor: Initial Implementation and Evaluation of a Novel Extubation Clinical Decision Support Tool
Airway Extubation
Primary: Evaluate Feasibility of Enrolling and Consenting Greater Than 50% of Eligible Patients — 30 Participants
N/A N=29 Electric Blower Based Ventilator Used During Procedural Sedation
Apnea During Procedural Sedation
Primary: Percentage of Time the Patient Will Experience Apnea — 11 % time in apnea of total study duration
N/A N=269 Evaluation of a Systematic Approach to Weaning From Mechanical Ventilation
Weaning Failure · Complication of Respirator [Ventilator]
Primary: Mortality — 10; 14 participants — p=0.03
N/A N=120 RCT of Mesh Versus Jet Nebulizers on Clinical Outcomes During Mechanical Ventilation in the Intensive Care Unit
Respiratory Insufficiency
Primary: Venilator Associated Events (VAE) — 44; 40; 4; 2 Participants
N/A N=16 Electrical Impedance Tomography for Optimization of Positive End-Expiratory Pressure: Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome · ARDS
Primary: Mechanical Power — 1.87; -2.50 J/min — p=.002
N/A N=16 Assessing Ventilator Safety in Patients on Pressure-Support Ventilation
Acute Respiratory Failure · Mechanical Ventilation Complication · Ventilator-Induced Lung Injury
Primary: Respiratory System Driving Pressure Measure by Servo Ventilator (DPrs-servo) — 12.3 centimeters of water
N/A N=320 Intensive Alveolar Recruitment Protocol After Cardiac Surgery
Ventilator Induced Lung Injury · Cardiac Disease · Acute Lung Injury
Primary: Severity of Pulmonary Complications in the Post-operative Period — 15; 26 percentage of participants — p=0.016
N/A N=30 Ability of Caregivers to Provide Ventilation With the SAVe Resuscitator in a Model
Pre-hospital Ventilation
Primary: Tidal Volume — 341.8; 27.5; 604.1 milliliters (mL) — p=<0.0001
Phase 3 N=10 Validation of the AVAPS AE Algorithm in Chronic Obstructive Pulmonary Disease (COPD) Patients
COPD · OSA
Primary: Control of Nocturnal Hypoventilation — 6.5; 6.7 kPa
N/A N=278 Retrospective Review of Mechanically Ventilated Patients Using a Continuous Data Collection System.
Mechanical Ventilation · Acute Respiratory Distress Syndrome · Hypoxic Respiratory Failure
Primary: Successful Extubation — 58; 222 Participants
N/A N=524 Sigh Ventilation to Increase Ventilator-Free Days in Victims of Trauma at Risk for Acute Respiratory Distress Syndrome
Acute Respiratory Distress Syndrome
Primary: Ventilator-free Days (VFDs) — 18.4; 16.1 days
N/A N=76 Evaluating Air Leak Detection in Intubated Patients
Critical Care
Primary: CO2 Leakage Above the ETT Cuff, Measured Over Time. — 0.09; 0.22 [CO2 mmHg*hour]/hour
N/A N=42 Vector Engineering Clinical
COPD
Primary: Average EPAP During Overnight PSG — 9.5 cmH2O
N/A N=22 Non-invasive Ventilation System in Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
Pulmonary Disease, Chronic Obstructive · Airflow Obstruction, Chronic · Chronic Obstructive Airway Disease
Primary: Device Tidal Volume — 180 mL
N/A N=90 AVAPS-AE Efficacy Study
Obesity Hypoventilation Syndrome
Primary: Daytime Partial Pressure of Carbon Dioxide in Arterial Blood (PaCO2) — 47.1; 51.8; 50.7; 40.7 mmHg
N/A N=751 Protocolized Post-Extubation Respiratory Support Study
Mechanical Ventilation Complication · Acute Respiratory Failure · Intubation Complication
Primary: Reintubation — 57; 52 Participants
N/A N=4,892 Ventilator-associated Pneumonia (VAP) Diagnostic Stewardship Trial
VAP - Ventilator Associated Pneumonia
Primary: Total Number of Deaths in the Pre vs Post-intervention Time Periods Among Study Participants Per 1000 Mechanically Ventilated Patient Days — 72; 73 Deaths per 1000…
Phase 3 N=38 Astral VAPS AutoEPAP Clinical Trial
Upper Airway Obstruction · Respiratory Insufficiency · Respiratory Failure
Primary: Oxygen Desaturation Index 4% (ODI4%) — 3.16; 7.61 events per hour — p=0.0134
Phase 4 N=129 Non Invasive Mechanical Ventilation in Acute Cardiogenic Pulmonary Edema
Acute Cardiogenic Pulmonary Edema
Primary: Number of Patients Who Were Intubated — 5; 4; 10 participants