5-Fluorouracil and MAL-PDT vs Surgery for Bowen's Disease: 4-Year Outcomes
Surgery kept skin cancer away better than two light-based treatments in this trial.
This multicenter RCT compared 5-fluorouracil, methylaminolevulinate photodynamic therapy (MAL-PDT), and surgical excision (SE) in 250 patien…
Surgery offered the highest chance of staying cancer-free for four years, while light-based treatments showed lower success rates in this st…
Machine learning model predicted FOLFIRINOX dose modifications in pancreatic ductal adenocarcinoma cohort
Most patients on strong pancreatic cancer chemo needed a dose change
This cohort study included 514 patients with pancreatic ductal adenocarcinoma treated at UCSF oncology clinics. XGBoost models showed AUCs r…
Over 60% of patients with pancreatic cancer needed a dose adjustment during treatment with FOLFIRINOX at UCSF clinics.
Tumor debulking plus chemotherapy did not improve overall survival in multiorgan metastatic colorectal cancer patients.
Surgery Doesn’t Extend Life for Advanced Colon Cancer
This randomized clinical trial enrolled 382 adult patients with multiorgan metastatic colorectal cancer across 27 hospitals in the Netherlan…
This large study shows that removing tumors in advanced colon cancer doesn’t help people live longer.